PerkinElmer

Protein-protein Interaction

OF

Accurately measure the function of proteins and gain new insights into protein-protein interaction (PPI) to modulate cellular processes. Inhibition and stabilization of these interactions using small molecules provides a mechanism that can be targeted for drug discovery.

We offer the technology to measure protein-protein interaction such as:

  • Transient and stable interactions
  • Low-to-high affinity interactions (pM to mM affinity)
  • Full-length protein-protein binding
  • Peptide-protein
  • Receptor dimerization
  • Protein-small molecule
  • Protein complex interactions

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Product Type
  • Accessories (6)
  • Instruments (6)
  • Reagents (122)
Antibody conjugates
  • Anti-6X His (7)
  • Anti-bovine IgA (1)
  • Anti-c-Myc (4)
  • Anti-C-tag (3)
  • Anti-DIG (2)
  • Anti-DNP (2)
  • Anti-FITC (3)
  • Anti-FLAG (6)
  • Anti-GFP (2)
  • Anti-goat IgG (1)
  • Anti-GST (5)
  • Anti-HA (4)
  • Anti-HRP (2)
  • Anti-human IgG (3)
  • Anti-MBP (1)
  • Anti-mouse IgG (3)
  • Anti-rabbit IgG (2)
  • Anti-rat IgG (2)
  • Anti-V5 (3)
  • Glutathione (3)
  • Nickel chelate (1)
  • Protein A (5)
  • Protein G (1)
  • Protein L (1)
  • Strep-Tactin (1)
  • Streptavidin (11)
  • Streptavidin/Anti-c-Myc (1)
  • Streptavidin/Anti-DIG (1)
  • Streptavidin/Anti-FITC (1)
  • Streptavidin/Anti-FLAG (1)
  • Streptavidin/Anti-GST (1)
  • Streptavidin/Anti-HA (1)
  • Streptavidin/Anti-mouse IgG (1)
  • Streptavidin/Anti-rabbit IgG (1)
  • Streptavidin/Nickel chelate (1)
  • Streptavidin/Protein A (1)
  • Unconjugated (2)
Application
  • Antibody binding (1)
  • Enzymatic (5)
  • Isotyping (1)
  • Multiplexing (2)
  • Protein Analysis & Detection (47)
  • Protein-nucleic acid interactions (4)
  • Protein-protein interactions (92)
Assay Points
  • 100 (5)
  • 10000 (11)
  • 500 (30)
  • 5000 (19)
  • 50000 (10)
Assay Target
  • COX-2 (3)
  • EGF (2)
  • EGFR (3)
  • FCGR3A (4)
  • Histone H4 (14)
  • MMP-7 (3)
  • PD-1 (3)
  • PD-L1 (4)
Assay Target Class
  • Fc-receptor (4)
  • Histone (14)
  • Protein (13)
Automation Compatible
  • Yes (125)
Detection Method
  • Absorbance (5)
  • Alpha (79)
  • DELFIA TRF (7)
  • Fluorescence (5)
  • Fluorescence Polarization (3)
  • Image-based Cytometry (1)
  • Label-free (2)
  • Luminescence (5)
  • Time-Resolved Fluorescence (TRF) (31)
  • TR-FRET (19)
Experimental type
  • In vitro (98)
Fluorophore
  • Eu-N1 (5)
  • Eu-W1024 (9)
  • Eu-W8044 (1)
  • Sm-N1 (1)
  • SureLight APC (4)
  • Tb-N1 (1)
  • ULight (8)
Format
  • Microplates (104)
Maximum Temperature (Celsius)
  • 40-50 (2)
  • 50-60 (2)
Molecular modification
  • Acetylation (14)
Product Brand Name
  • Alpha (6)
  • AlphaLISA (52)
  • AlphaPlex (16)
  • AlphaScreen (12)
  • DELFIA (7)
  • EnSight (1)
  • EnSpire (3)
  • EnVision (3)
  • LANCE (10)
  • LANCE SureLight (4)
  • LANCE Ultra (11)
  • Victor (3)
  • ViewLux (1)
Target Species
  • Human (17)
Therapeutic Area
  • Biologics/Bioprocess (4)
  • Cancer (13)
  • Epigenetics (14)
Volume
  • 0-50 (48)
  • 201-250 (32)
  • 451-500 (10)
  • Over 500 (10)

"Protein-protein Interaction" 1-50 of 134 Products and Services

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EnSight multimode plate-reader

EnSight Multimode Plate Reader

The EnSight multimode plate reader combines labeled, label-free & image-based cytometry technologies in a single benchtop platform. Imaging & online data analysis is fast: a 384-well plate can be imaged in less than 5 mins. The system’s modular design, combined with workflow-based Kaleido data acquisition & analysis software, gives a truly versatile plate reader that gets users productive quickly.
VictorX_ImageA_320px

VICTOR Multilabel Plate Reader

The next generation VICTOR X Multilabel Plate Reader platform delivers flexibility, speed and performance to research labs of all sizes.

EnSpire Alpha Plate Reader

The EnSpire Alpha Plate Reader provides proven Alpha technology to your lab at an affordable price and from the Alpha detection leader.

ViewLux uHTS Microplate Imager

The ViewLux® is the gold standard, ultra high-speed microplate imager, ideal for high throughput screening of compound libraries requiring the ultimate in speed, reliability and high quality data.

EnSpire Multimode Plate Reader

EnSpire® Multimode Plate Reader is designed to meet the demands of multi-user research environments, providing high performance technology and flexibility for a range of applications without compromising sensitivity. Combine this with our expertise and portfolio of reagents, PerkinElmer offers an unrivaled solution to your application needs.
EnVision_Alone_Left_Angle

EnVision Multilabel Reader

The EnVision Multilabel Plate Reader provides the highest speed, ultra-high throughput, and maximum sensitivity across  all detection technologies, so that your high throughput screening applications won’t be held back by unreliable results or equipment that can’t keep up to the demands of escalating workloads and new assays.
AlphaPlex Samarium Acceptor Beads

Anti-Human IgG AlphaPlex 645 (Sm) Acceptor beads

AlphaPlex™-645 (Samarium) Acceptor beads conjugated to anti-human IgG antibody, for use in Alpha no-wash multiplexing assays.
Price Range : 570.00 USD - 23400.00 USD

Protein A AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to Protein A. These beads can be used to capture antibodies that associate with Protein A.
Price Range : 571.00 USD - 23400.00 USD

Anti-human IgG (Fc specific) AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-human IgG antibody. These beads can be used to capture human IgG antibodies. The antibody conjugated to these beads is Fc-specific, and is a mouse polyclonal antibody.
Price Range : 571.00 USD - 23400.00 USD

Anti-DIG AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to a mouse monoclonal anti-Dig (digoxin) antibody. These beads can be used to capture Dig-labeled proteins, peptides, and other biomolecules to create AlphaLISA no-wash assays.
Price Range : 571.00 USD - 23400.00 USD

AlphaScreen DIG (Digoxin/Digoxigenin) Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-Dig (digoxin) conjugated AlphaScreen Acceptor beads. 
Price Range : 175.00 USD - 13400.00 USD

LANCE Ultra ULight™-anti-GST

Goat polyclonal anti-GST tag antibody labeled with ULight™ dye.
Price Range : 428.00 USD - 10800.00 USD
AlphaLISA Bromodomain Binding Assay kits

AlphaLISA BRD4_BD1 / H4 K12Ac Binding Kit

This kit is designed for the detection of binding activity between bromodomain-containing protein 4, Bromodomain1: BRD4 (BD1) and acetylated histone H4 peptide (H4 K12Ac) using a homogeneous AlphaLISA assay (no wash steps). The assay allows screening of BRD4 inhibitors with a highly-specific substrate.
Price Range : 796.00 USD - 4242.00 USD
AlphaPlex Samarium Acceptor Beads

Anti-6X His AlphaPlex 645 (Sm) Acceptor beads

AlphaPlex™-645 (Samarium) Acceptor beads conjugated to anti-6XHis antibody, for use in Alpha no-wash multiplexing assays.
Price Range : 570.00 USD - 23400.00 USD
Alphaplex_545_protein_coated

Streptavidin AlphaPlex™ 545 Acceptor Beads

Streptavidin-coated AlphaPlex™ 545 (Terbium) Acceptor beads, for use in Alpha no-wash multiplexing assays.
Price Range : 570.00 USD - 23400.00 USD

Anti-rat IgG (Fc specific) AlphaLISA® Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-rat IgG antibody. These beads can be used to capture rat IgG antibodies. The antibody is Fc-specific, and is a goat polyclonal F(ab')2 fragment.
Price Range : 571.00 USD - 23400.00 USD

AlphaScreen FITC (Fluorescein) Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-FITC conjugated AlphaScreen Acceptor beads. 
Price Range : 175.00 USD - 13400.00 USD
AlphaPlex-545-antibody-bead2

Anti-6X His AlphaPlex-545 (Tb) Acceptor beads

AlphaPlex-545 Acceptor beads conjugated to anti-6XHis antibody, for use in Alpha no-wash multiplexing assays.
Price Range : 570.00 USD - 23400.00 USD

Anti-goat IgG (Fc specific) AlphaLISA® Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-goat IgG antibody. These beads can be used to capture goat IgG antibodies. The antibody is Fc-specific, and is a rabbit polyclonal F(ab')2 fragment.
Price Range : 571.00 USD - 23400.00 USD
PerkinElmer

LANCE Eu-anti-C-tag antibody

Europium-labeled anti-C-tag antibodies for LANCE® TR-FRET assays. This mouse monoclonal IgG1 antibody recognizes N-terminal and C-terminal Protein C tagged fusion proteins. The anti-C-tag antibody can be used to capture C-tag proteins, and can be used in conjunction with LANCE ULight or SureLight™ APC-labeled reagents to create LANCE TR-FRET assays.
Price Range : 309.00 USD - 8700.00 USD
PerkinElmer

LANCE Eu-W1024 Anti-c-Myc

Europium-labeled anti-c-myc antibody, for capturing c-myc-tagged proteins in LANCE® TR-FRET assays.
Price Range : 229.00 USD - 13900.00 USD

AlphaScreen FLAG (M2) Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-FLAG conjugated AlphaScreen Acceptor beads. 
Price Range : 175.00 USD - 13400.00 USD
Alpha donor antibody coated

Anti-DNP Alpha Donor Beads

Alpha Donor beads conjugated to anti-DNP antibody. These beads can be used to capture DNP-labeled proteins, peptides, and small molecules.
Price Range : 1545.00 USD - 18000.00 USD

Anti-FITC AlphaLISA® Acceptor beads

AlphaLISA® Acceptor beads conjugated to mouse monoclonal anti-FITC antibody. These beads can be used to capture FITC-tagged and fluorescein-labeled biomolecules for AlphaLISA no-wash assays.
Price Range : 571.00 USD - 23400.00 USD
AlphaPlex-545-unconjugated

Unconjugated AlphaPlex-545 Acceptor Beads

Unconjugated AlphaPlex 545 (Terbium) Acceptor beads bear reactive aldehyde groups at their surface, allowing you to conjugate a wide variety of reagents using a simple reductive amination protocol.
Price Range : 1303.00 USD - 27400.00 USD
PerkinElmer

LANCE Eu-W1024 Anti-6xHis

Europium-labeled anti-6X His antibody, for capturing His-tagged proteins in LANCE® TR-FRET assays.
Price Range : 229.00 USD - 10800.00 USD

AlphaScreen GST Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-GST conjugated AlphaScreen Acceptor beads. This kit contains enough reagents to run 500 wells in 384-well format, using a 25 µL reaction volume.
Price Range : 175.00 USD - 13400.00 USD
Alpha binding assay principle

EGF/EGFR AlphaLISA Binding Kit

The AlphaLISA® EGF/EGFR Binding Kit is designed for the detection of binding activity between Human EGF and EGFR, using a homogeneous AlphaLISA assay (no wash steps). This assay can facilitate the design and development of therapeutics which competitively inhibit the EGF/EGFR interaction.
Price Range : 675.00 USD - 9500.00 USD

Streptavidin AlphaLISA® Acceptor beads

AlphaLISA® Acceptor beads conjugated to streptavidin. These beads can be used to capture biotinylated proteins, peptides, nucleic acids (DNA and RNA), and small molecules for AlphaLISA no-wash assays.
Price Range : 571.00 USD - 23400.00 USD

ULight anti-c-myc antibody

ULight labeled anti-c-myc antibody for LANCE® TR-FRET assays.
Price Range : 415.00 USD - 10500.00 USD

EGF-EGFR LANCE Ultra TR-FRET Binding Kit

This kit is designed for the detection of binding activity between Human EGF and EGFR using a homogeneous LANCE Ultra TR-FRET assay. This assay can facilitate the design and development of therapeutics which competitively inhibit EGF/EGFR interaction.
Price Range : 750.00 USD - 10000.00 USD

DELFIA® Eu-N1 Anti-6xHis

Europium-labeled anti-6X His antibody, for capturing His-tagged proteins in DELFIA® TRF assays. The anti-6xHis antibody is a purified mouse IgG1 monoclonal antibody. It is raised against a polypeptide containing a 6x histidine tag. The antibody has been shown to detect polyhistidine tags localized at the amino- or carboxyl-terminus.
Price Range : 451.00 USD - 4212.00 USD
PerkinElmer

AlphaLISA BRD4_BD2 / H4 K5,8,12,16Ac Binding Kit

This kit is designed for the detection of binding activity between bromodomain-containing protein 4, Bromodomain2: BRD4 (BD2) and acetylated histone H4 peptide (H4 K5,8,12,16Ac) using a homogeneous AlphaLISA assay (no wash steps). The assay allows screening of BRD4 inhibitors with a highly-specific substrate.
Price Range : 796.00 USD - 4242.00 USD
PerkinElmer

SureLight Allophycocyanin-anti-6His antibody, 1 mg, lyophilized

APC-labeled anti-His antibody, for capturing His-tagged proteins and peptides in LANCE TR-FRET assays.
List Price : 542.00 USD

AlphaScreen HA (Hemagglutinin) Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-HA (hemagglutinin) conjugated AlphaScreen Acceptor beads. 
Price Range : 175.00 USD - 13400.00 USD

ULight anti-FLAG

ULight™ labeled anti-FLAG antibodies for LANCE® TR-FRET assays. The anti-FLAG antibody is a purified mouse IgG2a monoclonal antibody (clone 29E4.G7.H11). The antibody is know to recognize C-terminal and N-terminal FLAG-tagged proteins.
Price Range : 422.00 USD - 10300.00 USD
AlphaPlex-545-antibody-bead2

Anti-human IgG AlphaPlex 545 Acceptor Beads

AlphaPlex™-545 (Terbium) Acceptor beads conjugated to anti-human IgG antibody, for use in Alpha no-wash multiplexing assays.
Price Range : 570.00 USD - 23400.00 USD
PerkinElmer

AlphaLISA BRD4_BD2 / H4 K5,12Ac Binding Kit

This kit is designed for the detection of binding activity between bromodomain-containing protein 4, Bromodomain2: BRD4 (BD2) and acetylated histone H4 peptide (H4 K5,12Ac) using a homogeneous AlphaLISA assay (no wash steps). The assay allows screening of BRD4 inhibitors with a highly-specific substrate.
Price Range : 796.00 USD - 4242.00 USD
AlphaLISA immunoassay kits

MMP-7 (human) AlphaLISA Detection Kit, 100 Assay Points

The AlphaLISA® immunoassay kit for human MMP7 enables the detection and quantitation of human pro- and active MMP-7 (hMMP-7) in serum, buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
List Price : 433.00 USD
AlphaLISA Bromodomain Binding Assay kits

AlphaLISA BRD4_BD1 / H4 K5,12Ac Binding Kit

This kit is designed for the detection of binding activity between bromodomain-containing protein 4, Bromodomain1: BRD4 (BD1) and acetylated histone H4 peptide (H4 K5,12Ac) using a homogeneous AlphaLISA assay (no wash steps). The assay allows screening of BRD4 inhibitors with a highly-specific substrate.
Price Range : 796.00 USD - 4242.00 USD

Protein G AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to Protein G. These beads can be used to capture antibodies that associate with Protein G.
Price Range : 571.00 USD - 23400.00 USD
AlphaLISA Bromodomain Binding Assay kits

AlphaLISA BRD4_BD2 / H4 K8,16Ac Binding Kit

This kit is designed for the detection of binding activity between bromodomain-containing protein 4, Bromodomain2: BRD4 (BD2) and acetylated histone H4 peptide (H4 K8,16Ac) using a homogeneous AlphaLISA assay (no wash steps). The assay allows screening of BRD4 inhibitors with a highly-specific substrate.
Price Range : 796.00 USD - 4242.00 USD

AlphaLISA anti-mouse IgG Acceptor beads

AlphaLISA Acceptor beads conjugated to anti-mouse IgG antibody. This antibody is not Fc-specific; for Fc-specific beads, please see product AL105.
Price Range : 548.00 USD - 22500.00 USD

Anti-FLAG AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-FLAG antibody. This mouse monoclonal M2 clone recognizes the FLAG sequence at the N-terminus, Met N-terminus, C-terminus, and internal sites.
Price Range : 571.00 USD - 23400.00 USD

Anti-V5 AlphaLISA Acceptor beads

AlphaLISA® Acceptor beads conjugated to anti-V5 antibody. The mouse monoclonal antibody detects proteins tagged with the V5 14-amino-acid tag (the 9-amino-acid tag has also been successfully bound by the antibody). 
Price Range : 571.00 USD - 23400.00 USD

LANCE Ultra ULight™-Streptavidin

Streptavidin labeled with ULight™ dye.
Price Range : 307.00 USD - 6000.00 USD

Anti-DNP AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-DNP antibody. These beads can be used to capture DNP-labeled proteins, peptides, and small molecules.
Price Range : 773.00 USD - 18000.00 USD
PerkinElmer

Eu-anti-V5 (LANCE TR-FRET)

Europium-labeled anti-V5 antibody, for capturing V5-tagged proteins in LANCE® TR-FRET assays. This Europium-labeled reagent can be used to capture V5-tagged proteins and peptides, and can be used in conjunction with LANCE® ULight or SureLight APC reagents to create TR-FRET no-wash assays for protein-protein interaction, protein detection, and enzymatic studies.
Price Range : 300.00 USD - 8400.00 USD

Anti-C-tag AlphaLISA Acceptor Beads

AlphaLISA Acceptor beads conjugated to anti-C-tag antibody. These beads can be used to capture C-tag proteins, and can be used in conjunction with Alpha Donor beads to create AlphaLISA no-wash assays.
Price Range : 571.00 USD - 23400.00 USD

Anti-HRP AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-HRP antibody. These beads can be used to capture HRP-fusion proteins for AlphaLISA no-wash assays.
Price Range : 554.00 USD - 22800.00 USD

"Protein-protein Interaction" 1-50 of 134 Products and Services

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