Eliminate the need for antibodies and reduce assay time with direct detection using our radiolabeled ligands, which provide for sensitive and quantitative measurement of binding.
High specific activity — The majority of our 125I-labeled ligands are offered at maximum specific activity. This means virtually every molecule of ligand provided in the stock vial is radiolabeled. For tritiated ligands (3H ligands), pick a ligand with specific activity above 20 Ci/mmol – all of our tritiated ligands meets or exceeds these requirements.
High purity — We offer highly-pure radioligands for the highest specific signal with low background in binding assays.
High selectivity — Our broad portfolio of agonists and antagonists offers many options for choosing the most selective compound for your receptor.
Validated for receptor binding — all of our radioligand products are tested for receptor binding during development. Additionally, many of our radioligands are used to QC our GPCR and receptor cell lines and cell membrane products.
35S t-butyl bicyclophosphorothionate (TBPS) is a picrotoxinin analog cage-convulsant that binds GABAA receptors with high affinity and high specificity. Its binding site is closely associated with the chloride ion channel, leading to its classification as a chloride ion channel blocking ligand.
Astemizole, [O-Methyl-3H]- will now be made available on a fresh lot schedule. NET1140025UC, NET1140250UC, and NET1140001MC will be available as a fresh lot twice a year on March 6 and August 7 in 2017.
Indolylacetic acid, also known as IAA, is a heterocyclic compound that is a phytohormone called auxins. IAA has many different effects, as all auxins do, such as inducing cell elongation and cell division with all subsequent results for plant growth and development.
This compound replaces NET1059. MK-912 is an alpha-2 adrenoceptor antagonist. This novel alpha-2 adrenoceptor antagonist radioligand [3H]-MK912 may be used in studies of the regulation of cardiovascular and CNS function.