Eliminate the need for antibodies and reduce assay time with direct detection using our radiolabeled ligands, which provide for sensitive and quantitative measurement of binding.
High specific activity — The majority of our 125I-labeled ligands are offered at maximum specific activity. This means virtually every molecule of ligand provided in the stock vial is radiolabeled. For tritiated ligands (3H ligands), pick a ligand with specific activity above 20 Ci/mmol – all of our tritiated ligands meets or exceeds these requirements.
High purity — We offer highly-pure radioligands for the highest specific signal with low background in binding assays.
High selectivity — Our broad portfolio of agonists and antagonists offers many options for choosing the most selective compound for your receptor.
Validated for receptor binding — all of our radioligand products are tested for receptor binding during development. Additionally, many of our radioligands are used to QC our GPCR and receptor cell lines and cell membrane products.
Vesamicol (AH5183) an acetylcholine uptake blocker in presynaptic vesicles,reduces the apparent activity of cholinergic neurons, but does not act at the post-synaptic ACh receptor. Vesamicol is a unique tool for investigating presynaptic mechanisms in cholinergic nerve terminals.
Serotonin (often referred to as 5-HT, short for 5-Hydroxy Tryptamine is a naturally occurring neurotransmitter which is tied to positive mood, certain involuntary muscle control, and countless other functions.
Vinorelbine (trade name Navelbine) is an anti-mitotic chemotherapy drug that is given as a treatment for some types of cancer, including breast cancer and non-small cell lung cancer. Vinorelbine is the first 5´NOR semi-synthetic vinca alkaloid.