LANCE TR-FRET

OF

A simple, highly-sensitive, and highly-reproducible platform for detection, quantitation and screening in microplate format. From biomarker detection assays to cAMP/GPCR studies to kinase and epigenetic assays, our LANCE® and LANCE Ultra TR-FRET technologies provide:

  • Time-resolved measurement for clearer signal resolution
  • Homogeneous (no wash steps, no separation steps)
  • Robust sensitivity
  • Long signal stability
  • Highly reproducible results

LANCE europium chelates are optimized for assay performance, signal level, energy transfer efficiency, background and sensitivity of the assay to interferences. The results are a superior S:B ratio and a very sensitive TR-FRET assay. You use less label and get more efficient use of assay reagents.

We also offer acceptor dyes that decrease steric hindrance while maximizing signal for labeled substrates, as well as those that provide a broad, antenna-like structure to help align fluorophores for optimal TR-FRET signal, making them excellent for measuring large binding interactions.

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"LANCE TR-FRET" 1-50 of 382 Products and Services

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LANCE Ultra mMCP-1, lyophilized (0.3ug)

LANCE Ultra mMCP-1, lyophilized (0.3ug)

List Price: 233.00 USD

LANCE Eu-W1284-Iodoacetamido Chelate and Eu Standard, 100µg

Europium labeling chelate for creating your own Europium-labeled biomolecules for use in LANCE TR-FRET assays. The iodoacetamido-activated chelate reacts primarily with free sulfhydryl groups, such as cysteines.

List Price: 2458.00 USD

LANCE Ultra Europium-anti-acetyl-Histone H3 Lysine 9 (H3K9ac), 10 µg

Europium-labeled monoclonal antibody recognizing human Histone H3 acetylated at lysine 9 (H3K9ac). For use in LANCE® Ultra epigenetic writer and eraser assays.

List Price: 3284.00 USD

Leptin (mouse), lyophilized (LANCE)

Mouse leptin standard, lyophilized, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Mouse Leptin Detection Kit, but can be ordered separately.

List Price: 226.00 USD

LANCE Eu-W1284-Iodoacetamido Chelate and Eu Standard, 1 mg

Europium labeling chelate for creating your own Europium-labeled biomolecules for use in LANCE TR-FRET assays. The iodoacetamido-activated chelate reacts primarily with free sulfhydryl groups, such as cysteines.

List Price: 12300.00 USD

LANCE Ultra Europium-anti-acetyl-Histone H3 Lysine 27 (H3K27ac) Antibody, 10 µg

Europium-labeled monoclonal antibody recognizing human Histone H3 acetylated at lysine 27 (H3K27ac). For use in LANCE® Ultra epigenetic writer and eraser assays.

List Price: 3284.00 USD

CHO HCP LANCE Ultra TR-FRET Detection Kit, 500 assay points

The LANCE® Ultra CHO HCP Detection Kit is designed for detection and quantitation of CHO host cell proteins in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 750.00 USD

CCL2/MCP-1α (mouse) LANCE Ultra TR-FRET Detection Kit, 5,000 assay points

The LANCE® Ultra Mouse CCL2/MCP-1α Detection Kit is designed for detection and quantitation of mouse Monocyte Chemoattractant Protein 1α in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 10000.00 USD

ULight anti-human IgG, 20 nmol

ULight™ labeled anti-human IgG antibody for LANCE® TR-FRET assays. The anti-human IgG antibody is a purified goat polyclonal antibody, and reacts with whole molecule human IgG.

List Price: 10200.00 USD

LANCE® Eu-W1024 Anti-phosphotyrosine (P-Tyr-100), 1 mg

Europium-labeled anti-phosphotyrosine (P-Tyr-100) antibody, for use in LANCE® TR-FRET kinase assays.

List Price: 9200.00 USD
LANCE biomarker detection assay principle

PAI-1 (human) LANCE Ultra TR-FRET Detection Kit, 500 Assay Points

The LANCE® Ultra Human PAI-1 Detection Kit is designed for detection and quantitation of human PAI-1 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 750.00 USD
LANCE biomarker detection assay principle

Insulin (human) LANCE Ultra TR-FRET Detection Kit, 500 Assay Points

The LANCE® Ultra Human Insulin Detection Kit is designed for detection and quantitation of human insulin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 750.00 USD

LANCE® Eu-W1024 phospho-(Ser) 14-3-3 binding motif antibody, 10 µg

Europium-labeled anti-phospho-(Ser) 14-3-3 motif antibody, for use in LANCE® TR-FRET kinase assays.

List Price: 3204.00 USD

Leptin (mouse) LANCE Ultra TR-FRET Detection Kit, 500 Assay Points

The LANCE® Ultra Mouse Leptin Detection Kit is designed for detection and quantitation of mouse leptin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 750.00 USD

LANCE Ultra MMP, lyophilized (0.3ug)

LANCE Ultra MMP, lyophilized (0.3ug)

List Price: 226.00 USD

LANCE Ultra Europium-anti-phospho-IkappaB-alpha (Ser32/36), 100 μg

Mouse monoclonal antibody labeled with the LANCE® Europium W-1024-ITC chelate. This antibody detects peptides derived from IkappaB-alpha phosphorylated at Ser32/36. IkappaB-alpha (Ser32/36) peptides can be phosphorylated by the IKKβ kinase. Sequence motif recognized: RHDSGLDSM

List Price: 4409.00 USD

ULight anti-human IgG, 0.2 nmol

ULight™ labeled anti-human IgG antibody for LANCE® TR-FRET assays. The anti-human IgG antibody is a purified goat polyclonal antibody, and reacts with whole molecule human IgG.

List Price: 403.00 USD

LANCE Ultra Europium-anti-phospho-Histone H3 (Ser10) Antibody, 10 µg

Mouse monoclonal antibody labeled with the LANCE Europium W-1024-ITC chelate. This antibody detects peptides derived from Histone H3 phosphorylated by Ser10. Histone H3 peptides can be phosphorylated by several kinases, including Aurora B. Sequence motif recognized: ARTKQTARKSTGGKAPRKQLAGCG

List Price: 1926.00 USD

LANCE Ultra Europium-anti-phospho-DNA Topoisomerase 2-alpha (Thr1342), 10 µg

Europium-labeled mouse monoclonal antibody recognizing human DNA Topoisomerase 2-alpha phosphorylated at Thr1342. Sequence motif recognized: DEK(pT)DDE

List Price: 1926.00 USD
LANCE biomarker detection assay principle

PAI-1 (human) LANCE Ultra TR-FRET Detection Kit, 10,000 Assay Points

The LANCE® Ultra Human PAI-1 Detection Kit is designed for detection and quantitation of human PAI-1 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 10000.00 USD

LANCE Eu-W1024 Biotin

Europium-labeled biotin for use in LANCE® TR-FRET assays.

List Price: 936.00 USD
generic antibody

IgG (rabbit), lyophilized (LANCE)

Rabbit IgG standard, for use in running standard curves in LANCE TR-FRET no-wash detection assays. This standard is already provided in the LANCE Ultra Rabbit IgG Detection Kit, but can be ordered separately.

List Price: 255.00 USD

LANCE® Eu-W1024 phospho-threonine-proline antibody, 10 µg

Europium-labeled anti-phospho-serine/threonine antibody, for use in LANCE® TR-FRET (TRF) kinase assays.

List Price: 1053.00 USD

LANCE® Eu-W1024 phospho-serine/threonine-phenylalanine antibody, 10 µg

Europium-labeled anti-phospho-serine/threonine-phenylalanine antibody, for use in LANCE® TR-FRET kinase assays.

List Price: 3806.00 USD
LANCE biomarker detection assay principle

Transferrin (human) LANCE Ultra TR-FRET Detection Kit, 10,000 Assay Points

The LANCE® Ultra Human Transferrin Detection Kit is designed for detection and quantitation of human transferrin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 10000.00 USD
LANCE biomarker detection assay principle

Albumin (human) LANCE Ultra TR-FRET Detection Kit, 10,000 Assay Points

The LANCE® Ultra Human Albumin Detection Kit is designed for detection and quantitation of human albumin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 10000.00 USD

VEGF (mouse) LANCE Ultra TR-FRET Detection Kit, 10,000 assay points

The LANCE® Ultra Mouse VEGF-A Detection Kit is designed for detection and quantitation of human CXCL1/GRO-α in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 10000.00 USD

LANCE Ultra Europium-anti-phospho-p70 S6K (Thr389) Antibody, 1.7 µg

Mouse monoclonal antibody labeled with the LANCE® Europium W-1024-ITC chelate. This antibody detects human p70 S6K phosphorylated at Thr389. p70 S6K is phosphorylated in vivo by mTOR. p70 S6K peptides are also phosphorylated by several kinases including COT, HGK, IKKε, IRAK1, IRAK4, MAP4K2, MINK, MST1, MST2, NEK1, NEK2, NEK6, NEK7, PEK, PLK1 and TAOK2. Sequence motif recognized: LGFTYVAP

List Price: 1444.00 USD

LANCE Ultra Europium-anti-phospho-Histone H3 (Thr3) Antibody, 100 µg

Rabbit monoclonal antibody labeled with the LANCE® Europium W-1024-ITC chelate. This antibody detects peptides derived from Histone H3 phosphorylated at Thr3. Histone H3 peptides can be phosphorylated by several kinases including RSK2. Sequence motif recognized: ARTKQTARKSTGGKAPRKQLAGCG

List Price: 6600.00 USD
LANCE biomarker detection assay principle

IGF-1 (human) LANCE Ultra TR-FRET Detection Kit, 500 Assay Points

The LANCE® Ultra Human IGF-1 Detection Kit is designed for detection and quantitation of Human IGF-1 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 750.00 USD

LANCE Ultra ULight™-anti-GST, 1 nmole

Goat polyclonal anti-GST tag antibody labeled with ULight™ dye.

List Price: 415.00 USD

ULight anti-FLAG, 100 nmol

ULight™ labeled anti-FLAG antibodies for LANCE® TR-FRET assays. The anti-FLAG antibody is a purified mouse IgG2a monoclonal antibody (clone 29E4.G7.H11). The antibody is know to recognize C-terminal and N-terminal FLAG-tagged proteins.

List Price: 10000.00 USD

LANCE Ultra Europium-anti-phospho-MEK1/2 (Ser217/221) Antibody, 100 µg

Rabbit polyclonal antibody labeled with the LANCE® Europium W-1024-ITC chelate. This antibody detects human MEK1 phosphorylated at Ser217 and Ser221. It also reacts with MEK1 singly phosphorylated at Ser217 or Ser221. MEK1 is phosphorylated in vivo by RAF1 and COT. Homologous phosphorylation sites are found in MEK2. Sequence motif recognized: GQLIDSMANSFVG

List Price: 6600.00 USD

LANCE Ultra Europium-anti-phospho-DNA Topoisomerase 2-alpha (Thr1342), 100 µg

Europium-labeled mouse monoclonal antibody recognizing human DNA Topoisomerase 2-alpha phosphorylated at Thr1342. Sequence motif recognized: DEK(pT)DDE

List Price: 6700.00 USD

LANCE Ultra Europium-anti-phospho-PKC (Ala25Ser) peptide Antibody, 10 µg

Mouse monoclonal antibody labeled with the LANCE® Europium chelate. This antibody detects phospho-Ser in a synthetic peptide (RFARKGSLRQKNV) only after the peptide is phosphorylated by PKC or PKA kinases. The synthetic peptide is derived from amino acids 19-31 of human PKCα in which Ala25 is mutated to Ser. Sequence motif recognized: RFARKG-pS-LRQKNV

List Price: 1926.00 USD

LANCE Ultra Europium-anti-methyl-Histone H3/H4 Arginine (H3/H4Rme pan) Antibody, 100 µg

Europium-labeled monoclonal antibody recognizing human Histone H3 and H4 methylated arginine residues. For use in LANCE® Ultra epigenetic writer and eraser assays.

List Price: 8200.00 USD

LANCE Ultra ULight™-PLK (Ser137) peptide, 0.5 nmole

ULight™-labeled synthetic peptide containing the amino acid residues surrounding Ser137 of polo-like kinase (PLK). The ULight-PLK peptide can be phosphorylated at Ser137 by a variety of kinases including Aurora A, PAK2, MSK1, PKA and PKC. Peptide core motif : RRRSLLE

List Price: 290.00 USD

LANCE Eu-W1024-ITC Chelate and Eu Standard, 1 mg

Europium labeling chelate for creating your own Europium-labeled biomolecules for use in LANCE TR-FRET assays. The ITC-activated chelate reacts primarily with free amino groups, such as lysines.

List Price: 12300.00 USD

Leptin (human) LANCE Ultra TR-FRET Detection Kit, 500 assay points

The LANCE® Ultra Human Leptin Detection Kit is designed for detection and quantitation of human leptin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 750.00 USD

LANCE® Eu-W1024 phospho-(Ser) 14-3-3 binding motif 4E2 antibody, 10 µg

Europium-labeled anti-phospho-(Ser) 14-3-3 binding motif 4E2 antibody, for use in LANCE® TR-FRET kinase assays.

List Price: 1725.00 USD
LANCE biomarker detection assay principle

Frataxin (human) LANCE Ultra TR-FRET Detection Kit, 10,000 Assay Points

The LANCE® Ultra Human Frataxin Detection Kit is designed for detection and quantitation of human frataxin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 10000.00 USD
Protein

Transferrin (human), lyophilized (LANCE)

Human transferrin standard, lyophilized, for use in running standard curves in LANCE TR-FRET no-wash detection assays. This standard is already provided in the LANCE Ultra Human Transferrin TR-FRET Detection Kit, but can be ordered separately.

List Price: 226.00 USD
List Price: 374.00 USD

LANCE Ultra Europium-anti-phospho-PKC (Ala25Ser) peptide Antibody, 100µg

Mouse monoclonal antibody labeled with the LANCE® Europium chelate. This antibody detects phospho-Ser in a synthetic peptide (RFARKGSLRQKNV) only after the peptide is phosphorylated by PKC or PKA kinases. The synthetic peptide is derived from amino acids 19-31 of human PKCα in which Ala25 is mutated to Ser. Sequence motif recognized: RFARKG-pS-LRQKNV

List Price: 6600.00 USD

CRP (human) LANCE Ultra TR-FRET Detection Kit, 500 assay points

The LANCE® Human CRP Detection Kit is designed for detection and quantitation of human C-reactive protein in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 750.00 USD
LANCE biomarker detection assay principle

IL-11 (human) LANCE Ultra TR-FRET Detection Kit, 10,000 Assay Points

The LANCE® Ultra Human IL-11 Detection Kit is designed for detection and quantitation of human interleukin-11 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 10000.00 USD

TNFα (mouse) LANCE Ultra TR-FRET Detection Kit, 500 assay points

The LANCE® Ultra Mouse TNFα Detection Kit is designed for detection and quantitation of mouse tumor necrosis factor α in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 750.00 USD

LANCE Ultra Europium-anti-phospho-mTOR (Ser2448) Antibody, 100 µg

Rabbit monoclonal antibody labeled with the LANCE® Europium W-1024-ITC chelate. This antibody detects peptides derived from mTOR phosphorylated at Ser2448. mTOR peptides can be phosphorylated by kinases MST1, p70 S6K and others. Sequence motif recognized: RSRTRTDSYSAGQSV

List Price: 6600.00 USD

LANCE Ultra Europium-anti-phospho-p70 S6K (Thr389) Antibody, 100 µg

Mouse monoclonal antibody labeled with the LANCE® Europium W-1024-ITC chelate. This antibody detects human p70 S6K phosphorylated at Thr389. p70 S6K is phosphorylated in vivo by mTOR. p70 S6K peptides are also phosphorylated by several kinases including COT, HGK, IKKε, IRAK1, IRAK4, MAP4K2, MINK, MST1, MST2, NEK1, NEK2, NEK6, NEK7, PEK, PLK1 and TAOK2. Sequence motif recognized: LGFTYVAP

List Price: 6600.00 USD
Protein

C-peptide (mouse), lyophilized (LANCE)

Mouse C-peptide standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the LANCE Ultra C-peptide TR-FRET Detection Kit, but can be ordered separately.

List Price: 498.00 USD

"LANCE TR-FRET" 1-50 of 382 Products and Services

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