LANCE TR-FRET

OF

A simple, highly-sensitive, and highly-reproducible platform for detection, quantitation and screening in microplate format. From biomarker detection assays to cAMP/GPCR studies to kinase and epigenetic assays, our LANCE® and LANCE Ultra TR-FRET technologies provide:

  • Time-resolved measurement for clearer signal resolution
  • Homogeneous (no wash steps, no separation steps)
  • Robust sensitivity
  • Long signal stability
  • Highly reproducible results

LANCE europium chelates are optimized for assay performance, signal level, energy transfer efficiency, background and sensitivity of the assay to interferences. The results are a superior S:B ratio and a very sensitive TR-FRET assay. You use less label and get more efficient use of assay reagents.

We also offer acceptor dyes that decrease steric hindrance while maximizing signal for labeled substrates, as well as those that provide a broad, antenna-like structure to help align fluorophores for optimal TR-FRET signal, making them excellent for measuring large binding interactions.

  • Products and Services

  • Resources, Events & More

Narrow your results
Antibody conjugates
  • Anti-6X His (2)
  • Anti-acetyl-lysine (1)
  • Anti-c-Myc (1)
  • Anti-FITC (6)
  • Anti-FLAG (7)
  • Anti-GST (2)
  • Anti-H3K27ac (1)
  • Anti-H3K27me2 (1)
  • Anti-H3K27me3 (1)
  • Anti-H3K36me2 (1)
  • Anti-H3K4 (1)
  • Anti-H3K4me1-2 (1)
  • Anti-H3K9/H3K27 (1)
  • Anti-H3K9ac (1)
  • Anti-H3K9me2 (1)
  • Anti-H4R3me (1)
  • Anti-HA (1)
  • Anti-human IgG (4)
  • Anti-methyl arginine (1)
  • Anti-mouse IgG (5)
  • Anti-O-linked-GlcNAc (1)
  • Anti-P-Akt (1)
  • Anti-P-PKA (1)
  • Anti-P-Ser (1)
  • Anti-P-Ser 14-3-3 (1)
  • Anti-P-Ser 14-3-3 4E2 (1)
  • Anti-P-Ser PKC (1)
  • Anti-P-Ser/Thr-Phe (1)
  • Anti-P-Ser/Thr-Pro (1)
  • Anti-P-Tyr-100 (1)
  • Anti-p53K382ac (1)
  • Anti-phospho-4EBP1 (1)
  • Anti-phospho-Acetyl-CoA-Carboxylase (1)
  • Anti-phospho-ATF-2 (1)
  • Anti-phospho-Crosstide (1)
  • Anti-phospho-glycogen synthase (1)
  • Anti-phospho-Histone H3 (2)
  • Anti-phospho-I?Ba (1)
  • Anti-phospho-MEK1/2 (1)
  • Anti-phospho-mTOR (1)
  • Anti-phospho-p38a (1)
  • Anti-phospho-p70S6K (1)
  • Anti-phospho-PKC (1)
  • Anti-phospho-PLK (1)
  • Anti-phospho-rpS6 (1)
  • Anti-phospho-threonine (1)
  • Anti-phospho-Threonine-Proline (1)
  • Anti-phospho-Topo IIa (1)
  • Anti-phospho-Tyrosine Hydroxylase (1)
  • Anti-rabbit IgG (5)
  • Biotin (1)
  • Protein G (1)
  • PT66 (2)
  • PY20 (1)
  • Streptavidin (4)
Application
  • cAMP (2)
  • Enzymatic (6)
  • Epigenetics (14)
  • Kinase (65)
  • Protein Analysis & Detection (184)
  • Protein-protein interactions (25)
Assay Points
  • 10000 (63)
  • 500 (64)
Assay Target
  • Adiponectin (3)
  • Albumin (3)
  • Aβ1-40 (3)
  • Bcl2 (2)
  • C-peptide (3)
  • cAMP (2)
  • CCL2 (4)
  • CCL3 (3)
  • CCL4 (3)
  • CCL5 (2)
  • CHO HCP (2)
  • CHO-P (2)
  • COL1A1 (2)
  • COX-2 (2)
  • CRP (2)
  • CXCL1 (3)
  • CXCL10 (3)
  • CXCL9 (3)
  • E.coli HCP (3)
  • EGF (2)
  • EGFR (3)
  • ErbB2 (3)
  • Fibronectin (3)
  • Frataxin (3)
  • GLP-1 (3)
  • Glucagon (3)
  • IFNα (2)
  • IFNγ (5)
  • IGF1 (3)
  • IgG (9)
  • IL-17A (3)
  • IL11 (2)
  • IL17A (2)
  • IL1α (2)
  • IL1β (4)
  • IL2 (2)
  • IL4 (1)
  • IL5 (2)
  • IL6 (6)
  • IL8 (2)
  • Insulin (3)
  • LC3B (3)
  • Leptin (5)
  • MIP1α (3)
  • MMP12 (3)
  • MMP3 (2)
  • MMP8 (3)
  • Nidogen-1 (3)
  • Oncostatin M (2)
  • PAI-1 (3)
  • PCSK9 (1)
  • PD-1 (2)
  • PD-L1 (2)
  • Perlecan (3)
  • Protein A (2)
  • PTEN (3)
  • Tau (3)
  • TNFα (5)
  • tPA (2)
  • Transferrin (3)
  • VEGF-A (5)
Assay Target Class
  • Antibody (9)
  • Cytokine (50)
  • Hormone (11)
  • Peptide (12)
  • Protein (75)
  • Receptor (3)
Automation Compatible
  • Yes (302)
Detection Method
  • Time-Resolved Fluorescence (TRF) (233)
  • TR-FRET (233)
Experimental type
  • In vitro (306)
Fluorophore
  • Eu-W1024 (66)
  • Eu-W1024-ITC (2)
  • Eu-W1284-Iodoacetamido (2)
  • Eu-W8044 (1)
  • Eu-W8044-DTA (1)
  • SureLight APC (6)
  • SureLight-APC (1)
  • ULight (50)
Format
  • Microplates (296)
Molecular modification
  • Acetylation (6)
  • GlcNAc (1)
  • Methylation (9)
  • Phosphorylation (64)
Product Family
  • LANCE (39)
  • LANCE SureLight (7)
  • LANCE Ultra (239)
Target Species
  • CHO (4)
  • Human (143)
  • Mouse (19)
  • Rabbit (3)
Therapeutic Area
  • Angiogenesis (7)
  • Autophagy (3)
  • Biologics/Bioprocess (18)
  • Cancer (37)
  • Cardiovascular (2)
  • Central Nervous System (8)
  • CNS & Neurologic (1)
  • Inflammation (51)
  • Metabolic (27)
Volume
  • 0-50 (36)
  • 51-100 (32)

"LANCE TR-FRET" 1-50 of 332 Products and Services

Sort
Per Page
Protein

PTEN (human), lyophilized (LANCE)

Human PTEN standard, lyophilized, for use in running standard curves in LANCE Ultra TR-FRET detection assays. This standard is already provided in the LANCE Ultra Human PTEN Detection Kit, but can be ordered separately.

List Price: 287.00 USD
LANCE biomarker detection assay principle

PTEN (human) LANCE Ultra TR-FRET Detection Kit, 500 Assay Points

The LANCE® Ultra Human PTEN Detection Kit is designed for detection and quantitation of human PTEN in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 750.00 USD

ULight anti-FLAG, 10 nmol

ULight™ labeled anti-FLAG antibodies for LANCE® TR-FRET assays. The anti-FLAG antibody is a purified mouse IgG2a monoclonal antibody (clone 29E4.G7.H11). The antibody is know to recognize C-terminal and N-terminal FLAG-tagged proteins.

List Price: 1450.00 USD
LANCE biomarker detection assay principle

LC3B (human) LANCE Ultra TR-FRET Detection Kit, 500 Assay Points

The LANCE® Ultra Human LC3B Detection Kit is designed for detection and quantitation of human microtubule-associated protein 1 light chain 3 isoform B (LC3B) in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 750.00 USD

LANCE Ultra Europium-anti-acetyl-Histone H3 Lysine 9 (H3K9ac)

Europium-labeled monoclonal antibody recognizing human Histone H3 acetylated at lysine 9 (H3K9ac). For use in LANCE® Ultra epigenetic writer and eraser assays.

List Price: 3284.00 USD
LANCE biomarker detection assay principle

PTEN (human) LANCE Ultra TR-FRET Detection Kit, 10,000 Assay Points

The LANCE® Ultra Human PTEN Detection Kit is designed for detection and quantitation of human PTEN in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 10000.00 USD

LANCE Ultra ULight™-mTOR (Ser2448) Peptide, 5 nmoles

ULight™-labeled synthetic peptide containing the amino acid residues surrounding Ser2448 of human mTOR. The ULight-mTOR peptide can be phosphorylated at Ser 2448 by the p70 S6 kinase and MST1 kinase. Peptide core motif : CAGAGRSRTRTDSYSAGQSV

List Price: 1131.00 USD

ULight anti-FLAG, 1 nmol

ULight™ labeled anti-FLAG antibodies for LANCE® TR-FRET assays. The anti-FLAG antibody is a purified mouse IgG2a monoclonal antibody (clone 29E4.G7.H11). The antibody is know to recognize C-terminal and N-terminal FLAG-tagged proteins.

List Price: 410.00 USD
Protein

C-peptide (mouse), lyophilized (LANCE)

Mouse C-peptide standard, lyophilized, for use in running standard curves in LANCE TR-FRET assays. This standard is already provided in the LANCE Ultra C-peptide TR-FRET Detection Kit, but can be ordered separately.

 

List Price: 498.00 USD

LANCE Ultra Protein A, lyophilized (0.3u

LANCE Ultra Protein A, lyophilized (0.3u

List Price: 226.00 USD

LANCE Eu-W1024 anti-FITC, 50 µg

Eu-W1024 labeled anti-FITC antibodies for LANCE® TR-FRET assays. The anti-FITC antibody is a purified mouse IgG2a monoclonal antibody.

List Price: 954.00 USD

LANCE Ultra ULight-p70 S6K (Thr389) Peptide

ULight™-labeled synthetic peptide containing the amino acid residues surrounding Thr389 of human p70 S6K. The ULight-p70 S6K peptide can be phosphorylated at Thr389 by several kinases including mTOR, COT, HGK, IKKε, IRAK1, IRAK4, MAP4K2, MINK, MST1, MST2, NEK1, NEK2, NEK6, NEK7, PEK, PLK1, and TAOK2. Phosphorylation motif: LGFTYVAP

List Price: 277.00 USD

LANCE Ultra htPA, lyophilized (0.3ug)

LANCE Ultra htPA, lyophilized (0.3ug)

List Price: 226.00 USD
Protein

MMP-8 (human), lyophilized (LANCE)

Human MMP-8 standard, lyophilized, for use in running standard curves in LANCE TR-FRET assays. This standard is already provided in the LANCE Ultra MMP-8 TR-FRET Detection Kit, but can be ordered separately.

List Price: 287.00 USD

ULight anti-FLAG, 100 nmol

ULight™ labeled anti-FLAG antibodies for LANCE® TR-FRET assays. The anti-FLAG antibody is a purified mouse IgG2a monoclonal antibody (clone 29E4.G7.H11). The antibody is know to recognize C-terminal and N-terminal FLAG-tagged proteins.

List Price: 10000.00 USD

LANCE Ultra ULight™-Streptavidin

Streptavidin labeled with ULight™ dye.

List Price: 5800.00 USD
LANCE biomarker detection assay principle

C-peptide (mouse/rat) LANCE Ultra TR-FRET Detection Kit, 10,000 Assay Points

The LANCE® Ultra Mouse C-peptide Detection Kit is designed for detection and quantitation of Mouse C-peptide in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 10000.00 USD
Protein

GLP-1 (7-36) (human), lyophilized (LANCE)

Human GLP-1 (7-36) standard, lyophilized, for use in running standard curves in LANCE TR-FRET no-wash detection assays. This standard is already provided in the LANCE Ultra Human GLP-1 (7-36) TR-FRET Detection Kit, but can be ordered separately.

List Price: 226.00 USD

LANCE® Eu-W1024 Anti-Rabbit IgG

Europium-labeled anti-rabbit IgG, for capturing antibodies in LANCE® TR-FRET assays.

List Price: 8600.00 USD

LANCE Ultra cAMP kit

The LANCE® Ultra cAMP assay is a homogeneous time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay designed to measure cAMP produced upon modulation of adenylyl cyclase activity by G-protein coupled receptors (GPCRs).

List Price: 600.00 USD

LANCE cAMP assay kit

LANCE® TR-FRET cAMP assay kit, for Gs- and Gi-coupled GPCR functional assays.

List Price: 1580.00 USD

SureLight Allophycocyanin-anti-FLAG antibody, 1 mg, lyophilized

APC-labeled anti-FLAG antibody, for capturing FLAG-tagged proteins and peptides in LANCE TR-FRET assays.

List Price: 527.00 USD
LANCE biomarker detection assay principle

VEGF (human) LANCE Ultra TR-FRET Detection Kit, 500 Assay Points

The LANCE® Ultra Human VEGF Detection Kit is designed for detection and quantitation of human VEGF in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 750.00 USD
LANCE biomarker detection assay principle

PAI-1 (human) LANCE Ultra TR-FRET Detection Kit, 10,000 Assay Points

The LANCE® Ultra Human PAI-1 Detection Kit is designed for detection and quantitation of human PAI-1 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 10000.00 USD

Residual Protein A LANCE Ultra TR-FRET Detection Kit, 500 assay points

The LANCE® Ultra Residual Protein A Detection Kit is designed for detection and quantitation of Residual Protein A in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 750.00 USD
LANCE biomarker detection assay principle

IgG (mouse) LANCE Ultra TR-FRET Detection Kit, 500 Assay Points

The LANCE® Ultra Mouse IgG Detection Kit is designed for detection and quantitation of Mouse IgG in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 750.00 USD

LANCE Eu-W1024 anti-FITC, 1 mg

Eu-W1024 labeled anti-FITC antibodies for LANCE® TR-FRET assays. The anti-FITC antibody is a purified mouse IgG2a monoclonal antibody.

List Price: 8400.00 USD

LANCE Ultra ULight™-CDK1 (Tyr15) Peptide

ULight™-labeled synthetic peptide derived from amino acids 9-20 of human cyclin-dependent kinase 1 (CDK1). The ULight-CDK1 peptide can be phosphorylated at Tyr15 by Lck kinase. Peptide sequence : CAGAGKIGEGTYGVVYK

List Price: 369.00 USD
LANCE biomarker detection assay principle

PD-1 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human PD-1 Detection Kit is designed for detection and quantitation of human PD-1 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: ***
LANCE biomarker detection assay principle

MMP-8 (human) LANCE Ultra TR-FRET Detection Kit, 500 Assay Points

The LANCE® Ultra Human MMP-8 Detection Kit is designed for detection and quantitation of human matrix metalloproteinase 8 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 750.00 USD

LANCE Ultra ULight™-anti-GST

Goat polyclonal anti-GST tag antibody labeled with ULight™ dye.

List Price: 10500.00 USD

LANCE Ultra Europium-anti-unmodified Histone H3 Lysine 9/Lysine 27 (H3K9/K27) Antibody

Europium-labeled monoclonal antibody recognizing human Histone H3 that is unmodified at lysine 9 and lysine 27 (H3K9/K27). For use in LANCE® Ultra epigenetic writer and eraser assays.

List Price: 3284.00 USD

LANCE Ultra Europium-anti-phospho-Histone H3 (Ser10) Antibody

Mouse monoclonal antibody labeled with the LANCE Europium W-1024-ITC chelate. This antibody detects peptides derived from Histone H3 phosphorylated by Ser10. Histone H3 peptides can be phosphorylated by several kinases, including Aurora B. Sequence motif recognized: ARTKQTARKSTGGKAPRKQLAGCG

List Price: 1926.00 USD
LANCE biomarker detection assay principle

PCSK9 (human) LANCE Ultra TR-FRET Detection Kit, 10,000 Assay Points

The LANCE® Ultra Human PCSK9 Detection Kit is designed for detection and quantitation of human Proprotein Convertase Subtilisin/Kexin Type 9 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 10000.00 USD

LANCE Ultra m/rIL17A, lyophilized(1.0ug)

LANCE Ultra m/rIL17A, lyophilized(1.0ug)

List Price: 226.00 USD
LANCE biomarker detection assay principle

C-peptide (mouse/rat) LANCE Ultra TR-FRET Detection Kit, 500 Assay Points

The LANCE® Ultra Mouse C-peptide Detection Kit is designed for detection and quantitation of Mouse C-peptide in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 750.00 USD

LANCE Ultra ULight™-Acetyl-CoA Carboxylase (Ser79) Peptide, 0.5 nmole

ULight™-labeled synthetic peptide derived from residues 73-85 of rat Acetyl-CoA Carboxylase in which Ser77 is mutated to Ala (also known as SAMS). The ULight-Acetyl-CoA Carboxylase peptide can be phosphorylated at Ser 79 by the AMPKα1 kinase. Peptide sequence : CHMRSAMSGLHLVKRR

List Price: 369.00 USD

LANCE Eu-W1024-ITC Chelate and Eu Standard, 100µg

Europium labeling chelate for creating your own Europium-labeled biomolecules for use in LANCE TR-FRET assays. The ITC-activated chelate reacts primarily with free amino groups, such as lysines.

List Price: 2458.00 USD

LANCE® Eu-W1024 Anti-phosphotyrosine (P-Tyr-100)

Europium-labeled anti-phosphotyrosine (P-Tyr-100) antibody, for use in LANCE® TR-FRET kinase assays.

List Price: 199.00 USD

IFN-? (human) LANCE Ultra TR-FRET Detection Kit, 10,000 assay points

The LANCE® Ultra Human IFN-α Detection Kit is designed for detection and quantitation of human interferon α in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 10000.00 USD
LANCE biomarker detection assay principle

COX-2 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human COX-2 Detection Kit is designed for detection and quantitation of human COX-2 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: ***

LANCE Ultra ULight™-CREBtide

CREBtide peptide (sequence: CKRREILSRRPSYRK) labeled with ULight™ dye. Synthetic peptide derived from human cAMP Response Element Binding (CREB) Protein (phosphorylation site: Ser133). CREB (Ser 133) can be phosphorylated by a variety of kinases including MSK1, PKA and PKC isoforms.

List Price: 298.00 USD
LANCE biomarker detection assay principle

Frataxin (human) LANCE Ultra TR-FRET Detection Kit, 10,000 Assay Points

The LANCE® Ultra Human Frataxin Detection Kit is designed for detection and quantitation of human frataxin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 10000.00 USD

LANCE Eu-W1024 Anti-c-Myc

Europium-labeled anti-c-myc antibody, for capturing c-myc-tagged proteins in LANCE® TR-FRET assays.

List Price: 13500.00 USD

SureLight Allophycocyanin-anti-GST antibody, 1 mg, lyophilized

APC-labeled anti-GST antibody, for capturing GST-tagged proteins and peptides in LANCE TR-FRET assays.

List Price: 468.00 USD

IFN-? (mouse) LANCE Ultra TR-FRET Detection Kit, 500 assay points

The LANCE® Ultra Mouse IFN-γ Detection Kit is designed for detection and quantitation of mouse interferon γ in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 750.00 USD
LANCE biomarker detection assay principle

PAI-1 (human) LANCE Ultra TR-FRET Detection Kit, 500 Assay Points

The LANCE® Ultra Human PAI-1 Detection Kit is designed for detection and quantitation of human PAI-1 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 750.00 USD

LANCE Ultra ULight™-Protein A

Protein A labeled with ULight™ dye.

List Price: 298.00 USD

Residual Protein A LANCE Ultra TR-FRET Detection Kit, 10,000 assay points

The LANCE® Ultra Residual Protein A Detection Kit is designed for detection and quantitation of Residual Protein A in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 10000.00 USD
LANCE biomarker detection assay principle

IgG (mouse) LANCE Ultra TR-FRET Detection Kit, 10,000 Assay Points

The LANCE® Ultra Mouse IgG Detection Kit is designed for detection and quantitation of Mouse IgG in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

List Price: 10000.00 USD

"LANCE TR-FRET" 1-50 of 332 Products and Services

Per Page