PerkinElmer

Iodinated Compounds

OF

Radiometric detection is considered the gold standard for many applications, from drug discovery and development to plant sciences. 125I labeled compounds are useful in both basic research and drug discovery where they are used as tracers in radioimmunoassays (RIA) and ligands in binding studies. 125I is particularly versatile as it emits both gamma and Auger electrons. This means that can be it counted either directly, without requiring scintillation, or by using a liquid scintillation counter. We offer a wide range of 125I labeled compounds as well as customized services to label your unique compound.

We also provide customized services to 131I labeled your compound of interest.

For Research and investigative use only.

  • Products and Services

  • Resources, Events & More

Narrow your results
Application
  • Drug Discovery & Development (76)
Therapeutic Area
  • Angiogenesis (8)
  • Cancer (8)
  • Cardiovascular (20)
  • CNS & Neurologic (37)
  • Diabetes (7)
  • Gastrointestinal (11)
  • Inflammation (25)
  • Metabolic Disorders (21)
  • Obesity (5)
  • Pain (9)
Product Brand Name
  • NEN Radiolabeled Ligands (76)
Detection Method
  • Radiometric (78)
Receptor Type
  • Adenosine (1)
  • Adrenoceptors (2)
  • Angiotensin (4)
  • Apelin (1)
  • Bombesin (2)
  • Calcitonin (2)
  • Calcium (2)
  • Chemokine (5)
  • Cholecystokinin (1)
  • Corticotropin-Releasing Factor (1)
  • Dopamine (1)
  • Endothelin (1)
  • Epidermal Growth Factor (1)
  • Ghrelin (1)
  • Glucagon (3)
  • Gonadotropin-releasing Hormone (1)
  • Growth Hormone (1)
  • Histamine (1)
  • Insulin (3)
  • Insulin-like Growth Factor (1)
  • Interleukin (1)
  • Melanin-Concentrating Hormone (1)
  • Melanocortin (1)
  • Melatonin (1)
  • Motilin (1)
  • Neuropeptide Y (3)
  • Neurotensin (1)
  • Nicotinic (3)
  • Orexin (1)
  • Oxytocin (1)
  • Platelet-Derived Growth Factor (1)
  • Potassium (1)
  • SK channels (1)
  • Somatostatin (2)
  • Tachykinin (3)
  • Thyroid Hormone (3)
  • Transforming Growth Factor (1)
  • Urotensin (1)
  • Vasoactive Intestinal Peptide (2)
  • Vasopressin (2)
Radionuclide
  • 125I (78)
Label Position
  • Nominally Labeled (73)
  • Specifically Labeled (5)
Concentration
  • 1.0 - 10 mCi/mL (1)
  • 1.12 mCi/mL (1)
  • 1.14 mCi/mL (1)
  • 152 µCi/mL (1)
  • 170.1 µCi/mL (1)
  • 171 µCi/mL (1)
  • 172.5 µCi/mL (1)
  • 173.9 µCi/mL (1)
  • 182 µCi/mL (2)
  • 2.93 MBq/mL (1)
  • 236 µCi (1)
  • 3.06 MBq/mL (1)
  • 3.22 MBq/mL (1)
  • 33.7 µCi (1)
  • 345 µCi/mL (3)
  • 353 µCi/mL (3)
  • 41.4 µCi/mL (2)
  • 42.5 µCi/mL (1)
  • 45.7 µCi/mL (1)
  • 50 µCi/mL (1)
  • 6.05 MBq/mL (1)
  • 79.2 µCi/mL (2)
  • 83.8 µCi/mL (1)
  • 85.1 µCi/mL (1)
  • 87.2 µCi/mL (1)
  • 87.4 µCi/mL (1)
  • 87.6 µCi/mL (1)
  • 87.9 µCi/mL (1)
  • 88.5 µCi/mL (1)
  • 93.2 µCi/mL (1)
  • <1.0 µCi/mL (3)
  • <100 µCi/mL (1)
Volume
  • 0-50 (8)
  • 51-100 (1)
  • 201-250 (1)

"Iodinated Compounds" 1-50 of 78 Products and Services

Sort
Alpha Bungarotoxin

Somatostatin, [125I]Tyr11

Somatostatin, labeled with 125I. Somatostatin binds somatostatin receptors, and inhibits the secretion of insulin and glucagon.
Price Range : 904.00 USD - 2107.00 USD
Alpha Bungarotoxin

IL-6 (human, recombinant), [125I]

Interleukin 6 (IL-6), labeled with 125I. IL-6 is a cytokine that regulates cell growth, cell differentiation, and immune response, and binds to the interleukin 6 receptor (IL6R; CD126).
Price Range : 1290.00 USD - 4316.00 USD
Alpha Bungarotoxin

Triiodothyronine, ([125I]-T3), Specific Activity: 1080-1320 µCi/µg

Triiodothyronine (T3) labeled with 125I. Triiodothyronine is a thyroid hormone that affects growth and development, body temperature, and heart rate. T3 detection by radioimmunoassay is a common test of thyroid gland function. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of ligand. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available, 4400 Ci/mmol if two labeling sites are available).
Price Range : 787.00 USD - 2272.00 USD
Alpha Bungarotoxin

Pancreatic Polypeptide (human), [125I]

Human pancreatic polypeptide (PP), labeled with 125I. Pancreatic polypeptide acts as an agonist at Pancreatic polypeptide receptors (Neuropeptide Y receptors), a class of GPCRs involved in appetite, circadian rhythm, and anxiety.
Price Range : 1011.00 USD - 2288.00 USD
Alpha Bungarotoxin

Neurokinin B, [125I]His, MePhe7

Neurokinin B (NKB), labeled with 125I on the histidine residue. Neurokinin B is involved in ovarian cycle regulation, and binds neurokinin 3 receptor (NK3R; tachykinin receptor 3), a GPCR involved in vascular remodeling, angiogenesis, and cancer.
Price Range : 980.00 USD - 2283.00 USD
Alpha Bungarotoxin

Apelin 13 [125I]

Apelin, labeled with 125 I. Apelin is the endogenous ligand for apelin receptors, and is used in receptor binding studies. Apelin 13 is a 13-amino acid peptide corresponding to residues 65-77.
Price Range : 998.00 USD - 3477.00 USD
Alpha Bungarotoxin

Neurotensin, [125I]Tyr3]

Neurotensin, labeled with 125I on the tyrosine 3 residue. Neurotensin functions as an agonist at neurotensin receptors. It is known to induce analgesia, hypothermia and increased locomotor activity. Neurotensin is also involved in the regulation of dopamine.
Price Range : 1005.00 USD - 2102.00 USD
Alpha Bungarotoxin

Guanosine 3`,5`-cyclic Phosphoric Acid, 2`-O-succinyl Iodotyrosine Methyl Ester, [125I]

cGMP, labeled with 125I on the tyrosine methyl ester group. I-125 labeled cGMP can be used as a tracer for radioimmunoassays to detect levels of endogenous cGMP in a sample.
Price Range : 379.00 USD - 6000.00 USD
Alpha Bungarotoxin

PACAP27, [125I]

Pituitary adenylate cyclase activating peptide-27 (PACAP-27), labeled with 125I. PACAP-27 binds the pituitary adenylate cyclase-activating polypeptide type I receptor (PAC1) and vasoactive intestinal peptide receptors (VPAC1 and VPAC2).
Price Range : 797.00 USD - 1670.00 USD
Alpha Bungarotoxin

Apamin [125I]His18-NH2

Apamin, labeled with 125I on histidine residue 18. Apamin is a neurotoxin that acts as an antagonist at calcium-activated potassium channels (SK channels).
Price Range : 910.00 USD - 1514.00 USD
Alpha Bungarotoxin

Orexin A, [125I]

Orexin A, labeled with 125I. Orexin A binds to orexin receptors (OX1 and OX2), which are potential drug targets for sleep disorders.
Price Range : 926.00 USD - 1987.00 USD
Alpha Bungarotoxin

Iodoaminopotentidine, [125I]

NEX431 [125I]-Aminopotentidine has been shown to work in receptor binding and autoradiography and is an antagonist for histamine (H2) receptors.
Price Range : 855.00 USD - 1931.00 USD
Alpha Bungarotoxin

α-Dendrotoxin [125I]

NEX434 [125I]- α-Dendrotoxinsare a class of neurotoxins produced by mamba snakes that block particular subtypes of voltage-gated potassium channels in neurons. Dendrotoxins enhance the release of acetylcholine at neuromuscular junctions.
Price Range : 1054.00 USD - 1678.00 USD
Alpha Bungarotoxin

Triiodothyronine, ([125I]-T3), Specific Activity: 3300 µCi/µg

Triiodothyronine (T3) labeled with 125I. Triiodothyronine is a thyroid hormone that affects growth and development, body temperature, and heart rate. T3 detection by radioimmunoassay is a common test of thyroid gland function. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of ligand. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available, 4400 Ci/mmol if two labeling sites are available).
Price Range : 744.00 USD - 2513.00 USD
Alpha Bungarotoxin

IP-10 (human, recombinant), [125I]-, Bolton-Hunter Labeled

Interferon gamma-induced protein 10 (IP-10; CXCL10), labeled with 125I. IP-10 binds the chemokine CXCR3 receptor, and is secreted in response to IFN-γ.
Price Range : 744.00 USD - 1804.00 USD
Alpha Bungarotoxin

α-Bungarotoxin, [125I]-Tyr54

α-bungarotoxin, labeled with 125I on tyrosine residue 54. α-bungarotoxin is a snake venom neurotoxin that acts as an antagonist at nicotinic acetylcholine receptors (nAChRs). This product as offered at two specific activities. Specific activity indicates how much radioactivity there is per molecule of ligand. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available). This indicates that virtually every molecule of ligand provided in the stock vial is radiolabeled.
Price Range : 566.00 USD - 2527.00 USD
Alpha Bungarotoxin

Human Growth Hormone, [125I]

Human growth hormone (HGH), labeled with 125I. Human growth hormone stimulates growth, cell reproduction and regeneration in animals. HGH functions to regulate body composition, fluid homeostasis, glucose and lipid metabolism, skeletal muscle and bone growth.
Price Range : 880.00 USD - 2359.00 USD
Alpha Bungarotoxin

Insulin-like Growth Factor-I (human, recombinant), 125I

Insulin-like growth factor 1 (IGF-1), labeled with 125I. IGF-1 acts as an agonist at the IGF-1 receptor, a receptor tyrosine kinase, that plays a role in growth, cancer, and aging. IGF-1 also binds the insulin receptor (IR), another receptor tyrosine kinase involved in glucose homeostasis, diabetes, and cancer.
Price Range : 675.00 USD - 1656.00 USD
Alpha Bungarotoxin

Gastric Inhibitory Polypeptide (human), [125I]

Gastric inhibitor polypeptide (GIP), labeled with 125I. GIP is a hormone that binds receptors found on beta cells in the pancreas.
Price Range : 943.00 USD - 1808.00 USD
Alpha Bungarotoxin

S365057, [Tyr 125I]

NEX396 S36057 is radioiodinated with no carrier added 125I using a lactoperoxidase procedure and is purified by reversed phase HPLC.
Price Range : 1312.00 USD - 2815.00 USD
Alpha Bungarotoxin

Recombinant Protein A, [125I]

Recombinant Protein A, labeled with 125I. I-125 labeled Protein A can be used as a general tracer to capture antibodies in radioimmunoassays (RIAs).
Price Range : 776.00 USD - 1257.00 USD
Alpha Bungarotoxin

Adenosine 3',5'-cyclic Phosphoric Acid, 2`-O-succinyl [125I]-Iodotyrosine Methyl Ester

cAMP, labeled with 125I on the tyrosine methyl ester group. I-125 labeled cAMP can be used as a tracer for radioimmunoassays to detect levels of endogenous cAMP in a sample or for GPCR functional assays.
Price Range : 379.00 USD - 4624.00 USD
Alpha Bungarotoxin

Motilin, [125I]

Motilin, labeled with 125I. Motilin is a peptide hormone that binds motilin receptors, and stimulates contraction of gut smooth muscle.
Price Range : 1153.00 USD - 2319.00 USD
Alpha Bungarotoxin

Iodo-(-)-Cyanopindolol, [125I]

Iodo-(-)-cyanopindolol, labeled with 125I. Cyanopindolol acts as an antagonist at β1 adrenergic receptors and serotonin 5-HT1A receptors.
Price Range : 1085.00 USD - 1770.00 USD
Alpha Bungarotoxin

Endothelin-1 (human, porcine), [125I]Tyr13

Endothelin-1 (ET-1), labeled with 125I on the tyrosine 13 residue. Endoethlin-1 is a vasoconstrictor that acts as an endogenous agonist at endothelin receptors. Endothelin receptors are a class of GPCRs that are potential drug targets for hypertension and cancer.
Price Range : 912.00 USD - 2510.00 USD
Alpha Bungarotoxin

Ghrelin (human), [His[125I]]

Ghrelin, labeled with 125I. Ghrelin is a peptide that regulates appetite and energy, and binds the ghrelin/growth hormone secretagogue receptor (GHS-R).
Price Range : 1350.00 USD - 2630.00 USD
Alpha Bungarotoxin

Glucagon, Receptor Grade, [125I]

Glucagon, labeled with 125I. This product is receptor grade, and was developed for use in receptor binding assays. Glucagon binds and activates glucagon receptor, a GPCR that is a potential drug target for diabetes, hyperplasia, and pancreatic disorders.
Price Range : 1028.00 USD - 2171.00 USD
Alpha Bungarotoxin

Thyroxine, ([125I]-T4), Specific Activity: 135-165 µCi/µg

Thyroxine (T4) labeled with 125I. Thyroxine is a thyroid hormone that is responsible for regulation or metabolism. T4 detection by radioimmunoassay is a common test of thyroid disease. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of thyroxine. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available, 4400 Ci/mmol if two labeling sites are available).
Price Range : 651.00 USD - 1816.00 USD
Alpha Bungarotoxin

LH-RH, [125I]-[D-Trp6]

Luteinizing Hormone Releasing Hormone (LHRH), labeled with 125I. LHRH binds LHRH receptors, and is a drug target for cancer therapy.
Price Range : 1047.00 USD - 2792.00 USD
Alpha Bungarotoxin

Iodo-Melatonin, 2-[125I]

Melatonin, labeled with 125I. Melatonin binds and activates melatonin receptors, a class of GPCRs that are potential drug targets for circadian rhythm sleep disorders and depression.
Price Range : 988.00 USD - 2498.00 USD
Alpha Bungarotoxin

ANGIOTENSIN II (human), [125I]-Tyr4 -50 μCi

Angiotensin II (human), labeled with 125I on the tyrosine (Tyr4) residue. Angiotensin II binds and activates angiotensin II receptor type 1 (AT1) and type 2 (AT2) receptors, a class of GPCRs important in vasoconstriction. Angiotensin II is a potential drug target for blood pressure regulation.
List Price : 2031.00 USD
Alpha Bungarotoxin

N-succinimidyl-3-(4-hydroxy-3-[125I]iodophenyl)propionate, Bolton-Hunter Reagent

Bolton-Hunter reagent, monoiodinated. This product is used to iodinate proteins that do not contain tyrosine residues. Bolton-Hunter reagent is the N-hydroxysuccinimide ester of iodinated p-hydroxyphenylpropionic acid. The active ester acylates terminal amino groups with the iodinated p-hydxyphenylpropionic residue, effectively introducing radioactive iodine into proteins and peptides. A non-oxidative technique, it is less harsh to proteins than alternative labeling methods. An anhydrous benzene A charcoal trap is provided with each vial.
Price Range : 582.00 USD - 1589.00 USD
Alpha Bungarotoxin

Ω-Conotoxin MVIIC, [125I]

Ω-Conotoxin MVIIC (ω-Conotoxin MVIIC), labeled with 125I. Ω-Conotoxin MVIIC is a neurotoxin that blocks calcium channels.
Price Range : 743.00 USD - 1951.00 USD
Alpha Bungarotoxin

Vasoactive Intestinal Polypeptide (human, porcine, rat), [125I]

Vasoactive intestinal polypeptide (VIP), labeled with 125I. VIP binds vasoactive intestinal peptide receptors VPAC1 and VPAC2, a group of GPCRs that are potential drug targets for nervous and endocrine disorders and several types of cancer.
Price Range : 961.00 USD - 2102.00 USD
Alpha Bungarotoxin

RTI-55, [125I]

RTI-55, labeled with 125I. RTI-55 is a nonselective dopamine reuptake inhibitor that is used to assess neuron degradation in Parkinson's disease and other neurodegenerative diseases.
Price Range : 904.00 USD - 1801.00 USD
Alpha Bungarotoxin

MIP-1α (human, recombinant), [125I]

Human recombinant macrophage inflammatory protein 1-alpha (MIP-1α; CCL3), labeled with 125I. MIP-1α is a cytokine involved in acute inflammation, and binds C-C chemokine receptors CCR1, CCR4, and CCR5.
Price Range : 735.00 USD - 3014.00 USD
Alpha Bungarotoxin

α-MSH, Nle4, D-Phe7, [125I]

α-Melanocyte-stimulating hormone (α-MSH), labeled with 125I. α-MSH is an endogenous hormone that acts as a non-selective full agonist of melanocortin receptors MC1, MC3, MC4, and MC5.
Price Range : 1036.00 USD - 2324.00 USD
Alpha Bungarotoxin

CGRP (human), [125I]

Calcitonin gene-related peptide (CGRP), labeled with 125I. CGRP binds calcitonin receptors.
Price Range : 797.00 USD - 1932.00 USD
Alpha Bungarotoxin

Bombesin, [125I]Tyr4

Bombesin, labeled with 125I on the tyrosine 4 residue. Bombesin is an endogenous agonist for bombesin receptors (BB1, BB2, BB3), and is also a tumor marker for certain cancers.
Price Range : 1041.00 USD - 2226.00 USD
Alpha Bungarotoxin

α-Bungarotoxin, [125I]-Tyr54-, High Specific Activity

α-bungarotoxin, labeled with 125I on tyrosine residue 54. α-bungarotoxin is a snake venom neurotoxin that acts as an antagonist at nicotinic acetylcholine receptors (nAChRs). This product as offered at two specific activities. Specific activity indicates how much radioactivity there is per molecule of ligand. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available). This indicates that virtually every molecule of ligand provided in the stock vial is radiolabeled.
Price Range : 644.00 USD - 2028.00 USD
Alpha Bungarotoxin

Thyroxine, ([125I]-T4), 5700 µCi/µg

Thyroxine (T4) labeled with 125I. Thyroxine is a thyroid hormone that is responsible for regulation or metabolism. T4 detection by radioimmunoassay is a common test of thyroid disease. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of thyroxine. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available, 4400 Ci/mmol if two labeling sites are available).
Price Range : 902.00 USD - 2649.00 USD
Alpha Bungarotoxin

Iodo-(±)-Cyanopindolol, [125I]

Iodo-(±)-cyanopindolol, labeled with 125I. Cyanopindolol acts as an antagonist at β1 adrenergic receptors and serotonin 5-HT1A receptors.
Price Range : 1317.00 USD - 2941.00 USD
Alpha Bungarotoxin

TGF-β1 (human, recombinant), [125I]

Transforming growth factor beta 1 (TGF-β1), labeled with 125I. TGF-β1 is a cytokine that is involved in cell growth, cell differentiation, and apoptosis.
Price Range : 845.00 USD - 2117.00 USD
Alpha Bungarotoxin

Bombesin (6-14), D-Tyr6[125I]

Bombesin (6-14), labeled with 125I. Bombesin binds and activates bombesin receptors BBR1, BBR2, and BBR3, and is a tumor marker for lung cancer, gastric cancer, pancreative cancer, and neuroblastoma.
Price Range : 1269.00 USD - 2385.00 USD
Alpha Bungarotoxin

SDF-1α (human, recombinant), [125I]

Stromal cell-derived factor 1 alpha (SDF-1α; CXCL12), labeled with 125I. SDF-1α binds the CXCR4 receptor.
Price Range : 744.00 USD - 1999.00 USD
Alpha Bungarotoxin

INSULIN (porcine), [125I], 10µCi (370kBq), Specific Activity:80-120µCi (2.96-4.44MBq)/µg

Insulin (porcine), labeled with 125I. Insulin is a peptide hormone that binds to insulin receptors to increase cellular uptake of glucose, increase DNA replication and protein synthesis, and modify enzymatic activity. This product is radioiodinated with 125I using a modification of the Hunter and Greenwood method and purified by ion-exchange column chromatography. This method predominantly labels tyrosine residues.
List Price : 833.00 USD
Alpha Bungarotoxin

Ornithine Vasotocin Analog, [125I]-OVTA)

Ornithine Vasotocin Analog (OVTA), labeled with 125I. OVTA binds oxytocin receptors, a hormone receptor involved in pregnancy, milk production, stress, social memory, and bonding.
Price Range : 1098.00 USD - 2226.00 USD
Alpha Bungarotoxin

Fractalkine (human, recombinant), 125I

Fractalkine (CX3CL1), labeled with 125I. Fractalkine binds to chemokine receptor CX3CR1, and is involved in the adhesion and migration of leukocytes.
Price Range : 959.00 USD - 2117.00 USD
Alpha Bungarotoxin

[125I]- Epidermal Growth Factor (human, rat)

NEX428 Epidermal Growth Factor is radioiodinated with no carrier added 125I using a lactoperoxidase procedure and is purified by reversed phase HPLC.
Price Range : 725.00 USD - 1599.00 USD
Alpha Bungarotoxin

2`-Deoxycytidine-5`-triphosphate, 5-[125I] iodo-, Tetraammonium Salt

Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that is used whenever DNA is synthesized, such as in the polymerase chain reaction. 125I dCTP may be used to produce cDNA transcripts of viral or mRNA.
Price Range : 1097.00 USD - 2742.00 USD

"Iodinated Compounds" 1-50 of 78 Products and Services