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Iodinated Compounds

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We provide 125I- and 131I-labeled compounds, including radioligands specific for receptor/ligand characterization for drug discovery/development and receptor distribution. Because 125I and 131I are gamma emitters, they can be counted directly without requiring scintillant. Additionally, because 125I emits Auger electrons, counting in a liquid scintillation counter is also possible.

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Application
  • Drug Discovery & Development (168)
Concentration
  • 1.0 - 10 mCi/mL (1)
  • 1.12 mCi/mL (2)
  • 1.14 mCi/mL (1)
  • 13.3 MBq/mL (1)
  • 152 µCi/mL (1)
  • 170.1 µCi/mL (2)
  • 171 µCi/mL (1)
  • 171.9 µCi/mL (2)
  • 172.5 µCi/mL (3)
  • 173.9 µCi/mL (1)
  • 182 µCi/mL (2)
  • 2.93 MBq/mL (2)
  • 236 µCi (3)
  • 3.06 MBq/mL (1)
  • 3.22 MBq/mL (1)
  • 33.7 µCi (2)
  • 345 µCi/mL (4)
  • 353 µCi/mL (5)
  • 41.4 µCi/mL (3)
  • 42.5 µCi/mL (1)
  • 45.7 µCi/mL (2)
  • 50 µCi/mL (1)
  • 6.05 MBq/mL (1)
  • 79.2 µCi/mL (2)
  • 83.8 µCi/mL (1)
  • 85.1 µCi/mL (1)
  • 86.3 µCi (1)
  • 87.2 µCi/mL (1)
  • 87.4 µCi/mL (1)
  • 87.6 µCi/mL (1)
  • 87.9 µCi/mL (1)
  • 88.5 µCi/mL (1)
  • 93.2 µCi/mL (2)
  • <1.0 µCi/mL (4)
  • <100 µCi/mL (2)
Detection Method
  • Radiometric (178)
Label Position
  • Nominally Labeled (166)
  • Specifically Labeled (15)
Product Brand Name
  • NEN Radiolabeled Ligands (178)
Radionuclide
  • 125I (180)
Receptor Type
  • 5-Hydroxytryptamine (2)
  • Adenosine (2)
  • Adrenoceptors (4)
  • Angiotensin (5)
  • Apelin (3)
  • Bombesin (4)
  • Calcitonin (3)
  • Calcium (4)
  • Chemokine (12)
  • Cholecystokinin (2)
  • Corticotropin-Releasing Factor (3)
  • Dopamine (2)
  • Endothelin (3)
  • Epidermal Growth Factor (4)
  • Ghrelin (2)
  • Glucagon (6)
  • Gonadotropin-releasing Hormone (2)
  • Growth Hormone (2)
  • Histamine (1)
  • Insulin (5)
  • Insulin-like Growth Factor (2)
  • Interleukin (4)
  • Melanin-Concentrating Hormone (2)
  • Melanocortin (4)
  • Melatonin (3)
  • Motilin (2)
  • Neuropeptide Y (6)
  • Neurotensin (2)
  • Nicotinic (7)
  • Orexin (2)
  • Oxytocin (3)
  • Peptide P518 (2)
  • Platelet-Derived Growth Factor (1)
  • Potassium (2)
  • SK channels (2)
  • Somatostatin (4)
  • Tachykinin (6)
  • Thyroid Hormone (6)
  • Transforming Growth Factor (3)
  • Urotensin (2)
  • Vasoactive Intestinal Peptide (4)
  • Vasopressin (4)
Therapeutic Area
  • Angiogenesis (12)
  • Cancer (22)
  • Cardiovascular (41)
  • CNS & Neurologic (84)
  • Diabetes (14)
  • Gastrointestinal (25)
  • Inflammation (60)
  • Metabolic Disorders (45)
  • Obesity (11)
  • Pain (22)
Volume
  • 0-50 (19)
  • 51-100 (1)
  • 201-250 (1)

"Iodinated Compounds" 1-50 of 181 Products and Services

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List Price : 1197.00 USD

MCP-1,[125I]- labeled, Bolton-Hunter Labeled, 25µCi

NEX313 Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). It is found at the site of tooth eruption and bone degradation. In the bone, CCL2 is expressed by mature osteoclasts and osteoblasts and is under the control of nuclear factor κB (NFκB).
List Price : 1646.00 USD

MIP-1α (human, recombinant), [125I], 25µCi

NEX298 [125I]-MIP-1α is useful in RIA, receptor studies and crosslinking experiments in the research into immune regulation.
List Price : 2318.00 USD
List Price : 805.00 USD

Thyroxine, ([125I]-T4), L-[125I]-, 100µCi (3.7MBq), Specific Activity: 135-165µCi (5.00-6.11MBq)/µg

NEX111 L-3,5-Diiodothyronine is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method and is purified by reversed phase HPLC.
List Price : 620.00 USD
List Price : 962.00 USD

MCP-1,[125I]- labeled, Bolton-Hunter Labeled, 5µCi

NEX313 Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). It is found at the site of tooth eruption and bone degradation. In the bone, CCL2 is expressed by mature osteoclasts and osteoblasts and is under the control of nuclear factor κB (NFκB).
List Price : 698.00 USD

MIP-1α (human, recombinant), [125I], 5µCi

NEX298 [125I]-MIP-1α is useful in RIA, receptor studies and crosslinking experiments in the research into immune regulation.
List Price : 700.00 USD
List Price : 1033.00 USD
List Price : 595.00 USD

Endothelin-1 (human, porcine), [125I]Tyr13, 5µCi

NEX259 [125I]-ET-1 will be useful as a tracer in RIA's for endothelin, and as a high specific activity ligand in receptor studies encompassing the areas of vasoconstriction and stroke, smooth muscle and renal function, and in the study of neurotransmitters in the CNS.
List Price : 869.00 USD

Ghrelin (human), [His[125I]], 10µCi

NEX388 Ghrelin is an acylated endogenous peptide which stimulates the release of growth hormone from the pituitary through an orphan G-protein-coupled receptor (GHS-R)7. Ghrelin is an appetite inducing hormone produced in the stomach and the upper portion of the small intestine. [ [125I]His ]Ghrelin (human), binds to GHS-R with high affinity.
List Price : 1285.00 USD
List Price : 1685.00 USD

Calcitonin [Tyr22] (salmon), [125I] 10 µCi

NEX423 [125I]-Calcitonin, [Tyr22] (s) is suitable for the use in radioimmunoassay as well as in the radio-receptor assay.
List Price : 846.00 USD

PDGF [125I] (human) 25 µCi

NEX433 [125I]-PDGF BB homodimer has been shown to work in RIA and receptor studies, using CHO cell line transfected with human PDGF B receptor, and human artery smooth muscle cells.
List Price : 1966.00 USD

Thyroxine, ([125I]-T4), L-[125I]-, 250µCi (9.25MBq), Specific Activity: 135-165µCi (5.00-6.11MBq)/µg

NEX111 L-3,5-Diiodothyronine is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method and is purified by reversed phase HPLC.
List Price : 925.00 USD
List Price : 554.00 USD

CGP 42112A, [125I]-, 25µCi

NEX324 Extremely high selectivity makes [125I]-CGP 42112A very useful for competitive binding assays, isolation of receptors, and autoradiography.
List Price : 1669.00 USD

Somatostatin, [125I]Tyr11, 10µCi

NEX389 Somatostatin is a cyclic neuropeptide found in the brain, pancreas and hypothalamus and inhibits the release of growth hormone. [125I ] Tyr11 somatostatin binds to the receptors on RINm5F insolinoma cells with high affinity and inhibits the secretion of insulin from pancreatic b cells.
List Price : 861.00 USD

Thyroxine, ([125I]-T4), L-[125I]-, 500µCi (18.5MBq), Specific Activity: 135-165µCi (5.00-6.11MBq)/µg

NEX111 L-3,5-Diiodothyronine is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method and is purified by reversed phase HPLC.
List Price : 1730.00 USD

Lysergic Acid Diethylamide, 2-[125I]iodo-(+), 50µCi

NEX199 Preparations have been shown to be active in binding to the serotonin receptors. LSD affects a large number of the G protein coupled receptors, including all dopamine receptor subtypes, and all adrenoreceptor subtypes, as well as many others. LSD binds to most serotonin receptor subtypes except for 5-HT3 and 5-HT4.
List Price : 2013.00 USD
List Price : 1903.00 USD

α-Bungarotoxin, [125I]-Tyr54-, High Specific Activity, 250 µCi

α-bungarotoxin extracted from venom of the Taiwanese banded krait (Bungarus multicinctus) binds the nicotinic acetylcholine receptor found at the neuromuscular junction and the 7 nicotinic acetylcholine receptor in the brain.
List Price : 1931.00 USD

Fractalkine (human, recombinant), 25µCi

NEX368 Fractalkine is the first member of a new class of chemokines. [125I]-Fractalkine binds with high affinity to the CX3CR1 receptor. [125I]-Fractalkine will be useful for the localization and characterization of CXCR1 receptors.
List Price : 2017.00 USD

RTI-55, [125I]-, 25µCi (925kBq)

NEX272 [125I]-RTI-55 is an excellent radioligand for the study of the dopamine transporter sites using either tissue homogenates or autoradiographic methods--especially in regions of low receptor density.
List Price : 861.00 USD

Goat anti-rabbit IgG, [125I], 250µCi (9.25MBq)

Affinity purified goat anti-rabbit IgG is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method1 and is purified by gel filtration chromatography. This method predominantly labels tyrosine residues.
List Price : 893.00 USD

Bombesin, [125I]Tyr4-, 10µCi (370kBq)

NEX258 [125I]-Bombesin will be useful as a tracer in RIAs for bombesin like peptides, and as a high specific activity ligand in receptor studies.
List Price : 992.00 USD

Insulin-like Growth Factor-I (human, recombinant), 5µCi

NEX241 IGF-1 is produced primarily by the liver as an endocrine hormone as well as in target tissues in a paracrine/autocrine fashion. Production is stimulated by growth hormone (GH) and can be retarded by undernutrition, growth hormone insensitivity, lack of growth hormone receptors, or failures of the downstream signalling pathway post GH receptor including SHP2 and STAT5B.
List Price : 643.00 USD
List Price : 1098.00 USD
List Price : 2557.00 USD

Lysergic Acid Diethylamide, 2-[125I]iodo-(+), 250µCi

NEX199 Preparations have been shown to be active in binding to the serotonin receptors. LSD affects a large number of the G protein coupled receptors, including all dopamine receptor subtypes, and all adrenoreceptor subtypes, as well as many others. LSD binds to most serotonin receptor subtypes except for 5-HT3 and 5-HT4.
List Price : 4574.00 USD

Iodo-Melatonin, 2-[125I], 250µCi

NEX236 2-[125I]-iodomelatonin has been used to identify, characterize and localize melatonin binding sites in the brain and peripheral tissues.
List Price : 2379.00 USD

2'-deoxycytidine-5'-triphosphate, 5-[125I]Iodo-

Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that is used whenever DNA is synthesized, such as in the polymerase chain reaction. 125I dCTP may be used to produce cDNA transcripts of viral or mRNA.
List Price : 1631.00 USD

Glucagon, Receptor Grade, [125I]-, 10µCi

NEX207 Glucagon is radioiodinated with no carrier added 125I by a lactoperoxidase procedure and is purified by reversed phase HPLC. [125I]-Glucagon consists of an approximately 1:1 ratio of Tyr10 and Tyr13 labeled glucagon. Met27 is in its native thioether form.
List Price : 979.00 USD

Bombesin (6-14), D-Tyr6[125I], 10µCi

NEX377 [D-Tyr6[125I]-, βAla11, Phe13, Nle14]-Bombesin (6-14) is a high affinity agonist to the human Orphan Bombesin Receptor Subtype 3 (hBRS-3).
[D-Tyr6[125I]-, bAla11, Phe13, Nle14]-Bombesin (6-14) will be a useful tool to study the pharmacology of this orphan receptor as well as the natural ligand for this receptor.
List Price : 1208.00 USD

α-Bungarotoxin, [125I]-Tyr54-, 500µCi (18.5MBq)

α-bungarotoxin extracted from venom of the Taiwanese banded krait (Bungarus multicinctus) binds the nicotinic acetylcholine receptor found at the neuromuscular junction and the 7 nicotinic acetylcholine receptor in the brain.
List Price : 2106.00 USD

ACTH (1-39) 23Tyr [125I], 50 µCi

[125I]ACTH is lyophilized from an acetic acid solution (0.1%) containing bovine serum albumin (0.25%), lactose (5%), L-cysteine hydrochloride (0.1%) and aprotinin (0.3TIU/ml).
List Price : 4474.00 USD

Peptide YY, (Porcine), ([125I]-PYY), 50µCi

NEX240 Synthetic Peptide YY is radioiodinated with no-carrier-added 125I using a modification of the chloramine-T method.
List Price : 2215.00 USD

S365057, [Tyr 125I], 10 µCi

NEX396 S36057 is radioiodinated with no carrier added 125I using a lactoperoxidase procedure and is purified by reversed phase HPLC.
List Price : 1249.00 USD

α-Bungarotoxin, [125I]-Tyr54-, 50µCi (1.85MBq)

α-bungarotoxin extracted from venom of the Taiwanese banded krait (Bungarus multicinctus) binds the nicotinic acetylcholine receptor found at the neuromuscular junction and the 7 nicotinic acetylcholine receptor in the brain.
List Price : 539.00 USD
List Price : 3312.00 USD

ANGIOTENSIN I (human), [125I]Tyr4-, 50µCi (1.85MBq), Species Activity:2200Ci (81.4TBq/mmol)

NEX101 Angiotensin, a protein, causes blood vessels to constrict, and drives blood pressure up. It is part of the renin-angiotensin system, which is a major target for drugs that lower blood pressure. Angiotensin also stimulates the release of aldosterone from the adrenal cortex.
List Price : 1956.00 USD
List Price : 1721.00 USD

AB-MECA, [125I]-(4-Amino-3-[125I]iodobenzyl-5`-N-)-, 50µCi

AB-MECA is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method and is purified by reversed phase HPLC.
List Price : 2208.00 USD

Ghrelin (human), [His[125I]], 25µCi

NEX388 Ghrelin is an acylated endogenous peptide which stimulates the release of growth hormone from the pituitary through an orphan G-protein-coupled receptor (GHS-R)7. Ghrelin is an appetite inducing hormone produced in the stomach and the upper portion of the small intestine. [ [125I]His ]Ghrelin (human), binds to GHS-R with high affinity.
List Price : 2505.00 USD

2`-Deoxycytidine-5`-triphosphate, 5-[125I]iodo-, Tetraammonium Salt, 1 mCi (37 MBq),

Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that is used whenever DNA is synthesized, such as in the polymerase chain reaction. 125I dCTP may be used to produce cDNA transcripts of viral or mRNA.
List Price : 2612.00 USD

Goat anti-rabbit IgG, [125I], 100µCi (3.7MBq)

Affinity purified goat anti-rabbit IgG is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method1 and is purified by gel filtration chromatography. This method predominantly labels tyrosine residues.
List Price : 762.00 USD
List Price : 1513.00 USD

"Iodinated Compounds" 1-50 of 181 Products and Services

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