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Iodinated Compounds

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We provide 125I- and 131I-labeled compounds, including radioligands specific for receptor/ligand characterization for drug discovery/development and receptor distribution. Because 125I and 131I are gamma emitters, they can be counted directly without requiring scintillant. Additionally, because 125I emits Auger electrons, counting in a liquid scintillation counter is also possible.

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Application
  • Drug Discovery & Development (168)
Concentration
  • 1.0 - 10 mCi/mL (1)
  • 1.12 mCi/mL (2)
  • 1.14 mCi/mL (1)
  • 13.3 MBq/mL (1)
  • 152 µCi/mL (1)
  • 170.1 µCi/mL (2)
  • 171 µCi/mL (1)
  • 171.9 µCi/mL (2)
  • 172.5 µCi/mL (3)
  • 173.9 µCi/mL (1)
  • 182 µCi/mL (2)
  • 2.93 MBq/mL (2)
  • 236 µCi (3)
  • 3.06 MBq/mL (1)
  • 3.22 MBq/mL (1)
  • 33.7 µCi (2)
  • 345 µCi/mL (4)
  • 353 µCi/mL (5)
  • 41.4 µCi/mL (3)
  • 42.5 µCi/mL (1)
  • 45.7 µCi/mL (2)
  • 50 µCi/mL (1)
  • 6.05 MBq/mL (1)
  • 79.2 µCi/mL (2)
  • 83.8 µCi/mL (1)
  • 85.1 µCi/mL (1)
  • 86.3 µCi (1)
  • 87.2 µCi/mL (1)
  • 87.4 µCi/mL (1)
  • 87.6 µCi/mL (1)
  • 87.9 µCi/mL (1)
  • 88.5 µCi/mL (1)
  • 93.2 µCi/mL (2)
  • <1.0 µCi/mL (4)
  • <100 µCi/mL (2)
Detection Method
  • Radiometric (178)
Label Position
  • Nominally Labeled (166)
  • Specifically Labeled (15)
Product Brand Name
  • NEN Radiolabeled Ligands (178)
Radionuclide
  • 125I (180)
Receptor Type
  • 5-Hydroxytryptamine (2)
  • Adenosine (2)
  • Adrenoceptors (4)
  • Angiotensin (5)
  • Apelin (3)
  • Bombesin (4)
  • Calcitonin (3)
  • Calcium (4)
  • Chemokine (12)
  • Cholecystokinin (2)
  • Corticotropin-Releasing Factor (3)
  • Dopamine (2)
  • Endothelin (3)
  • Epidermal Growth Factor (4)
  • Ghrelin (2)
  • Glucagon (6)
  • Gonadotropin-releasing Hormone (2)
  • Growth Hormone (2)
  • Histamine (1)
  • Insulin (5)
  • Insulin-like Growth Factor (2)
  • Interleukin (4)
  • Melanin-Concentrating Hormone (2)
  • Melanocortin (4)
  • Melatonin (3)
  • Motilin (2)
  • Neuropeptide Y (6)
  • Neurotensin (2)
  • Nicotinic (7)
  • Orexin (2)
  • Oxytocin (3)
  • Peptide P518 (2)
  • Platelet-Derived Growth Factor (1)
  • Potassium (2)
  • SK channels (2)
  • Somatostatin (4)
  • Tachykinin (6)
  • Thyroid Hormone (6)
  • Transforming Growth Factor (3)
  • Urotensin (2)
  • Vasoactive Intestinal Peptide (4)
  • Vasopressin (4)
Therapeutic Area
  • Angiogenesis (12)
  • Cancer (22)
  • Cardiovascular (41)
  • CNS & Neurologic (84)
  • Diabetes (14)
  • Gastrointestinal (25)
  • Inflammation (60)
  • Metabolic Disorders (45)
  • Obesity (11)
  • Pain (22)
Volume
  • 0-50 (19)
  • 51-100 (1)
  • 201-250 (1)

"Iodinated Compounds" 1-50 of 181 Products and Services

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List Price : 2557.00 USD
List Price : 1633.00 USD

Cholecystokinin Octapeptide, [125I]-, Bolton-Hunter Labeled, 50µCi

NEX203 CCK-8 mediates a number of physiological processes, including digestion and satiety. It is located in the small intestine, and detects the presence of fat in the chyme. As a neuropeptide, CCK mediates satiety by acting on the CCK receptors distributed widely throughout the central nervous system.
List Price : 3214.00 USD

Vasopressin (Linear), V-1A Antagonist (Phenylacetyl1, 0-Me-D-Tyr2, [125I-Arg6]-),50µCi

NEX310 [125I]-Phenylacetyl-D-Tyr(Me)-Phe-Gln-Asn-Arg-Pro-Arg-Tyr-NH2 is useful in receptor studies and autoradiography for the localization and characterization of Vasopressin V1A receptors.
List Price : 2038.00 USD
List Price : 1721.00 USD

Vasopressin (Linear), V-1A Antagonist (Phenylacetyl1, 0-Me-D-Tyr2, [125I-Arg6]-),10µCi

NEX310 [125I]-Phenylacetyl-D-Tyr(Me)-Phe-Gln-Asn-Arg-Pro-Arg-Tyr-NH2 is useful in receptor studies and autoradiography for the localization and characterization of Vasopressin V1A receptors.
List Price : 918.00 USD

Glucagon, Receptor Grade, [125I]-, 50µCi

NEX207 Glucagon is radioiodinated with no carrier added 125I by a lactoperoxidase procedure and is purified by reversed phase HPLC. [125I]-Glucagon consists of an approximately 1:1 ratio of Tyr10 and Tyr13 labeled glucagon. Met27 is in its native thioether form.
List Price : 2067.00 USD
List Price : 980.00 USD
List Price : 2251.00 USD

Ghrelin (human), [His[125I]], 25µCi

NEX388 Ghrelin is an acylated endogenous peptide which stimulates the release of growth hormone from the pituitary through an orphan G-protein-coupled receptor (GHS-R)7. Ghrelin is an appetite inducing hormone produced in the stomach and the upper portion of the small intestine. [ [125I]His ]Ghrelin (human), binds to GHS-R with high affinity.
List Price : 2505.00 USD

Somatostatin-14 (human, recombinant), Receptor Grade, 50µCi

NEX446 Tyr11 Somatostatin-14 is radioiodinated with no-carrier-added 125I using amodified lactoperoxidase procedure and is purified by reversed phase HPLC. This method predominantly labels tyrosine residues.
List Price : 2083.00 USD

Fractalkine (human, recombinant), 10µCi

NEX368 Fractalkine is the first member of a new class of chemokines. [125I]-Fractalkine binds with high affinity to the CX3CR1 receptor. [125I]-Fractalkine will be useful for the localization and characterization of CXCR1 receptors.
List Price : 872.00 USD

Endothelin-1 (human, porcine), [125I]Tyr13, 5µCi

NEX259 [125I]-ET-1 will be useful as a tracer in RIA's for endothelin, and as a high specific activity ligand in receptor studies encompassing the areas of vasoconstriction and stroke, smooth muscle and renal function, and in the study of neurotransmitters in the CNS.
List Price : 869.00 USD

Insulin (porcine), Receptor Grade, [125I]TyrA14], 10µCi

[125I]TyrA14 Insulin has been proven to be active in a receptor binding assay using cultured human fibroblasts as described.8 It may also be used in radioimmunoassay.
List Price : 1098.00 USD

2`-Deoxycytidine-5`-triphosphate, 5-[125I]iodo-, Tetraammonium Salt, 1 mCi (37 MBq),

Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that is used whenever DNA is synthesized, such as in the polymerase chain reaction. 125I dCTP may be used to produce cDNA transcripts of viral or mRNA.
List Price : 2612.00 USD

Ghrelin (human), [His[125I]], 10µCi

NEX388 Ghrelin is an acylated endogenous peptide which stimulates the release of growth hormone from the pituitary through an orphan G-protein-coupled receptor (GHS-R)7. Ghrelin is an appetite inducing hormone produced in the stomach and the upper portion of the small intestine. [ [125I]His ]Ghrelin (human), binds to GHS-R with high affinity.
List Price : 1285.00 USD

α-Bungarotoxin, [125I]-Tyr54-, High Specific Activity, 250 µCi

α-bungarotoxin extracted from venom of the Taiwanese banded krait (Bungarus multicinctus) binds the nicotinic acetylcholine receptor found at the neuromuscular junction and the 7 nicotinic acetylcholine receptor in the brain.
List Price : 1931.00 USD

Thyroxine, ([125I]-T4), L-[125I]-, 250µCi (9.25MBq), Specific Activity: 135-165µCi (5.00-6.11MBq)/µg

NEX111 L-3,5-Diiodothyronine is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method and is purified by reversed phase HPLC.
List Price : 925.00 USD

Adenosine 3',5'-cyclic Phosphoric Acid, 2`-O-succinyl [125I]-Iodotyrosine Methyl Ester-, 50µCi

Adenosine 3',5'-cyclic Phosphoric Acid, 2'-O-succinyl, [125I]-Iodotyrosine Methyl Ester- Adenosine is an inhibitory neurotransmitter, believed to play a role in promoting sleep and suppressing arousal, with levels increasing with each hour an organism is awake.
List Price : 4404.00 USD

MCP-1,[125I]- labeled, Bolton-Hunter Labeled, 5µCi

NEX313 Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). It is found at the site of tooth eruption and bone degradation. In the bone, CCL2 is expressed by mature osteoclasts and osteoblasts and is under the control of nuclear factor κB (NFκB).
List Price : 698.00 USD

Endothelin-1 (human, porcine), [125I]Tyr13, 10µCi

NEX259 [125I]-ET-1 will be useful as a tracer in RIA's for endothelin, and as a high specific activity ligand in receptor studies encompassing the areas of vasoconstriction and stroke, smooth muscle and renal function, and in the study of neurotransmitters in the CNS.
List Price : 1197.00 USD
List Price : 1033.00 USD
List Price : 1685.00 USD
List Price : 1731.00 USD

Lysergic Acid Diethylamide, 2-[125I]iodo-(+), 10µCi

NEX199 Preparations have been shown to be active in binding to the serotonin receptors. LSD affects a large number of the G protein coupled receptors, including all dopamine receptor subtypes, and all adrenoreceptor subtypes, as well as many others. LSD binds to most serotonin receptor subtypes except for 5-HT3 and 5-HT4.
List Price : 838.00 USD
List Price : 805.00 USD

Angiotensin II, [125I]-Sar1, Ile8], 50µCi

NEX248 [125I]-Sar1-Ile8-Angiotensin II is an angiotensin receptor antagonist which binds to a single class of receptors. [125I]-Sar1-Ile8-Angiotensin II is useful for studying AII receptors when an antagonist ligand is preferred, for receptor localization studies using autoradiographic techniques and for drug screening programs.
List Price : 2174.00 USD

2'-deoxycytidine-5'-triphosphate, 5-[125I]Iodo-

Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that is used whenever DNA is synthesized, such as in the polymerase chain reaction. 125I dCTP may be used to produce cDNA transcripts of viral or mRNA.
List Price : 1631.00 USD
List Price : 1098.00 USD

Somatostatin-14 (human, recombinant), Receptor Grade, 10 µCi

NEX446 Tyr11 Somatostatin-14 is radioiodinated with no-carrier-added 125I using amodified lactoperoxidase procedure and is purified by reversed phase HPLC. This method predominantly labels tyrosine residues.
List Price : 859.00 USD

Vasopressin, [125I]Tyr2, Arg8-, 50µCi (1.85MBq)

NEX128 [Arg8]-Vasopressin is radioiodinated using no carrier added 125I, by a modification of the Hunter and Greenwood method and is purified by reversed phase HPLC.
List Price : 2046.00 USD

[125I]Tyr0-Corticotropin Releasing Factor (ovine), 50 µCi

NEX217 Corticotropin-releasing hormone (CRH), originally named corticotropin-releasing factor (CRF), and also called corticoliberin, is a polypeptide hormone and neurotransmitter involved in the stress response.
List Price : 2448.00 USD

RTI-55, [125I]-, 25µCi (925kBq)

NEX272 [125I]-RTI-55 is an excellent radioligand for the study of the dopamine transporter sites using either tissue homogenates or autoradiographic methods--especially in regions of low receptor density.
List Price : 861.00 USD

Vasoactive Intestinal Polypeptide (human, porcine, rat), [125I], 50µCi

VIP is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method and purified by reversed phase HPLC. This method predominantly labels tyrosine residues. 
List Price : 2002.00 USD
List Price : 1197.00 USD

[125I]Tyr0-Corticotropin Releasing Factor (ovine), 10 µCi

NEX217 Corticotropin-releasing hormone (CRH), originally named corticotropin-releasing factor (CRF), and also called corticoliberin, is a polypeptide hormone and neurotransmitter involved in the stress response.
List Price : 1140.00 USD
List Price : 957.00 USD

Calcitonin [Tyr22] (salmon), [125I] 10 µCi

NEX423 [125I]-Calcitonin, [Tyr22] (s) is suitable for the use in radioimmunoassay as well as in the radio-receptor assay.
List Price : 846.00 USD

Goat anti-rabbit IgG, [125I], 100µCi (3.7MBq)

Affinity purified goat anti-rabbit IgG is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method1 and is purified by gel filtration chromatography. This method predominantly labels tyrosine residues.
List Price : 762.00 USD

SDF-1α (human, recombinant), [125I]-, 5µCi

NEX346 SDF-1 a acts at the CXCR4 (fusin or LESTR) receptor. 125I-SDF-1 a competes with SDF-1 a in CXCR4 receptor binding assays.
List Price : 708.00 USD

Epidermal Growth Factor (Murine), [125I]-,50µCi

Epidermal growth factor or EGF is a growth factor that plays an important role in the regulation of cell growth, proliferation, and differentiation by binding to its receptor EGFR.
List Price : 1943.00 USD

Iodoaminopotentidine, [125I], 25 µCi

NEX431 [125I]-Aminopotentidine has been shown to work in receptor binding and autoradiography and is an antagonist for histamine (H2) receptors.
List Price : 1839.00 USD

α-MSH, Nle4, D-Phe7, [125I], 10µCi

NEX352 α-MSH is a highly potent and metabolically stable analog of α-MSH.7 [125I]-[Nle4, D-Phe7]-α-MSH can be used to label all subtypes of melanocortin receptors with high affinity and low non-specific binding.
List Price : 987.00 USD

Endothelin-1 (human, porcine), [125I]Tyr13, 50µCi

NEX259 [125I]-ET-1 will be useful as a tracer in RIA's for endothelin, and as a high specific activity ligand in receptor studies encompassing the areas of vasoconstriction and stroke, smooth muscle and renal function, and in the study of neurotransmitters in the CNS.
List Price : 2390.00 USD

CGP 42112A, [125I]-, 5µCi

NEX324 Extremely high selectivity makes [125I]-CGP 42112A very useful for competitive binding assays, isolation of receptors, and autoradiography.
List Price : 707.00 USD

"Iodinated Compounds" 1-50 of 181 Products and Services

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