Iodinated Compounds

OF

We provide 125I- and 131I-labeled compounds, including radioligands specific for receptor/ligand characterization for drug discovery/development and receptor distribution. Because 125I and 131I are gamma emitters, they can be counted directly without requiring scintillant. Additionally, because 125I emits Auger electrons, counting in a liquid scintillation counter is also possible.

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Application
  • Drug Discovery & Development (187)
Concentration
  • 1.0 - 10 mCi/mL (1)
  • 1.11 mCi/mL (1)
  • 1.12 mCi/mL (2)
  • 1.14 mCi/mL (1)
  • 100 - 1000 µCi/mL (1)
  • 13.3 MBq/mL (1)
  • 152 µCi/mL (1)
  • 164 µCi/mL (2)
  • 170.1 µCi/mL (2)
  • 171 µCi/mL (1)
  • 171.9 µCi/mL (2)
  • 172.5 µCi/mL (3)
  • 173.9 µCi/mL (1)
  • 180.5 µCi/mL (1)
  • 182 µCi/mL (2)
  • 184.9 µCi/mL (2)
  • 2.93 MBq/mL (2)
  • 236 µCi (3)
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  • 3.22 MBq/mL (1)
  • 33.7 µCi (2)
  • 345 µCi/mL (4)
  • 353 µCi/mL (5)
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  • 41.4 µCi/mL (3)
  • 42.5 µCi/mL (1)
  • 45.7 µCi/mL (2)
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  • 6.05 MBq/mL (1)
  • 77.7 µCi/mL (1)
  • 79.2 µCi/mL (2)
  • 83.8 µCi/mL (1)
  • 85.1 µCi/mL (1)
  • 86.3 µCi (1)
  • 87.2 µCi/mL (1)
  • 87.4 µCi/mL (1)
  • 87.6 µCi/mL (1)
  • 87.9 µCi/mL (1)
  • 88.5 µCi/mL (1)
  • 93.2 µCi/mL (2)
  • <1.0 µCi/mL (4)
  • <100 µCi/mL (2)
Detection Method
  • Radiometric (203)
Label Position
  • Nominally Labeled (189)
  • Specifically Labeled (17)
Product Brand Name
  • NEN Radiolabeled Ligands (201)
Radionuclide
  • 125I (204)
Receptor Type
  • 5-Hydroxytryptamine (2)
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  • Insulin-like Growth Factor (2)
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Therapeutic Area
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Volume
  • 0-50 (167)
  • 51-100 (14)
  • 101-150 (1)
  • 201-250 (14)
  • 451-500 (10)

"Iodinated Compounds" 1-50 of 206 Products and Services

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Atrial Natriuretic Peptide (human) [125I] α-ANP, 25 µCi

This product will be discontinued from our catalog portfolio on January 1, 2017 and will move to our custom iodination portfolio at that time.
List Price : 2547.00 USD

Endothelin-1 (human, porcine), [125I]Tyr13, 5µCi

NEX259 [125I]-ET-1 will be useful as a tracer in RIA's for endothelin, and as a high specific activity ligand in receptor studies encompassing the areas of vasoconstriction and stroke, smooth muscle and renal function, and in the study of neurotransmitters in the CNS.
List Price : 790.00 USD

CGP 42112A, [125I]-, 5µCi

NEX324 Extremely high selectivity makes [125I]-CGP 42112A very useful for competitive binding assays, isolation of receptors, and autoradiography.
List Price : 642.00 USD
List Price : 1981.00 USD

2`-Deoxycytidine-5`-triphosphate, 5-[125I]iodo-, Tetraammonium Salt, 100µCi (3.7MBq)

Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that is used whenever DNA is synthesized, such as in the polymerase chain reaction. 125I dCTP may be used to produce cDNA transcripts of viral or mRNA.
List Price : 949.00 USD

Insulin (human, recombinant), [125I], 50 µCi

[125I]-Insulin (h) is suitable for the use in radioimmunoassay as well as receptor binding assay. [125I]-Insulin (h) is radioiodinated with no carrier added 125I using the LPO iodination procedure and is purified by reversed phase HPLC.
List Price : 1829.00 USD

Glucagon, Receptor Grade, [125I]-, 50µCi

NEX207 Glucagon is radioiodinated with no carrier added 125I by a lactoperoxidase procedure and is purified by reversed phase HPLC. [125I]-Glucagon consists of an approximately 1:1 ratio of Tyr10 and Tyr13 labeled glucagon. Met27 is in its native thioether form.
List Price : 1879.00 USD
List Price : 817.00 USD

CGP 42112A, [125I]-, 25µCi

NEX324 Extremely high selectivity makes [125I]-CGP 42112A very useful for competitive binding assays, isolation of receptors, and autoradiography.
List Price : 1517.00 USD
List Price : 1574.00 USD
List Price : 1088.00 USD

Insulin-like Growth Factor-I (human, recombinant), 5µCi

NEX241 IGF-1 is produced primarily by the liver as an endocrine hormone as well as in target tissues in a paracrine/autocrine fashion. Production is stimulated by growth hormone (GH) and can be retarded by undernutrition, growth hormone insensitivity, lack of growth hormone receptors, or failures of the downstream signalling pathway post GH receptor including SHP2 and STAT5B.
List Price : 584.00 USD

Eledoisin, [125I]- Lys4-, Bolton-Hunter Labeled, 10µCi

This product will be discontinued from our catalog portfolio on January 1, 2017 and will move to our custom iodination portfolio at that time.
List Price : 1552.00 USD

Fractalkine (human, recombinant), 10µCi

NEX368 Fractalkine is the first member of a new class of chemokines. [125I]-Fractalkine binds with high affinity to the CX3CR1 receptor. [125I]-Fractalkine will be useful for the localization and characterization of CXCR1 receptors.
List Price : 793.00 USD

S365057, [Tyr 125I], 25 µCi

NEX396 S36057 is radioiodinated with no carrier added 125I using a lactoperoxidase procedure and is purified by reversed phase HPLC.
List Price : 2437.00 USD

Iodo-Melatonin, 2-[125I], 250µCi

NEX236 2-[125I]-iodomelatonin has been used to identify, characterize and localize melatonin binding sites in the brain and peripheral tissues.
List Price : 2163.00 USD

TNF-α (human, recombinant), [125I]-rTNFα, 10µCi

This product will be discontinued from our catalog portfolio on January 1, 2017 and will move to our custom iodination portfolio at that time.
List Price : 848.00 USD

IL-6 (human, recombinant), [125I], 25µCi

NEX269 Interleukin-6 (IL-6) is a protein that in humans is encoded by the IL6 gene. IL-6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation.
List Price : 3567.00 USD

GLP-1 (7-36), [125I]-, 50µCi (1.85MBq)

NEX308 Glucagon-like peptide-1 (GLP-1) is derived from the transcription product of the proglucagon gene. The major source of GLP-1 in the body is the intestinal L cell that secretes GLP-1 as a gut hormone. The biologically active forms of GLP-1 are: GLP-1-(7-37) and GLP-1-(7-36)NH2.
List Price : 1926.00 USD

RTI-121, [125I]-, 250µCi (9.25MBq)

This product will be discontinued from our catalog portfolio on January 1, 2017 and will move to our custom iodination portfolio at that time.
List Price : 1916.00 USD

SDF-1α (human, recombinant), [125I]-, 25µCi

NEX346 SDF-1 a acts at the CXCR4 (fusin or LESTR) receptor. 125I-SDF-1 a competes with SDF-1 a in CXCR4 receptor binding assays.
List Price : 1730.00 USD

Atrial Natriuretic Factor (rat), [125I]Tyr28], 50 µCi

This product will be discontinued from our catalog portfolio on January 1, 2017 and will move to our custom iodination portfolio at that time.
List Price : 2300.00 USD
List Price : 870.00 USD
List Price : 2008.00 USD

TRIIODOTHYRONINE, ([125I]-Reverse T3), L-3,3`,5`-[125I]-, 500µCi (18.5MBq)

This product will be discontinued from our catalog portfolio on January 1, 2017 and will move to our custom iodination portfolio at that time.
List Price : 1976.00 USD

Goat anti-rabbit IgG, [125I], 100µCi (3.7MBq)

Affinity purified goat anti-rabbit IgG is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method1 and is purified by gel filtration chromatography. This method predominantly labels tyrosine residues.
List Price : 693.00 USD

Insulin-like Growth Factor-I (human, recombinant), 25µCi

NEX241 IGF-1 is produced primarily by the liver as an endocrine hormone as well as in target tissues in a paracrine/autocrine fashion. Production is stimulated by growth hormone (GH) and can be retarded by undernutrition, growth hormone insensitivity, lack of growth hormone receptors, or failures of the downstream signalling pathway post GH receptor including SHP2 and STAT5B.
List Price : 1434.00 USD
List Price : 864.00 USD

Adenosine 3',5'-cyclic Phosphoric Acid, 2`-O-succinyl [125I]-Iodotyrosine Methyl Ester-, 50µCi

Adenosine 3',5'-cyclic Phosphoric Acid, 2'-O-succinyl, [125I]-Iodotyrosine Methyl Ester- Adenosine is an inhibitory neurotransmitter, believed to play a role in promoting sleep and suppressing arousal, with levels increasing with each hour an organism is awake.
List Price : 4003.00 USD

[125I]Tyr0-Corticotropin Releasing Factor (ovine), 50 µCi

NEX217 Corticotropin-releasing hormone (CRH), originally named corticotropin-releasing factor (CRF), and also called corticoliberin, is a polypeptide hormone and neurotransmitter involved in the stress response.
List Price : 2225.00 USD

IP-10 (human, recombinant), [125I]-, Bolton-Hunter Labeled, 25µCi

NEX348 IP-10 acts at the CXCR3 receptor and attracts T cells, particularly activated T cells.
List Price : 1562.00 USD
List Price : 1720.00 USD

MIP-1α (human, recombinant), [125I], 5µCi

NEX298 [125I]-MIP-1α is useful in RIA, receptor studies and crosslinking experiments in the research into immune regulation.
List Price : 636.00 USD
List Price : 1532.00 USD

TRIIODOTHYRONINE, ([125I]-Reverse T3), L-3,3`,5`-[125I]-, 250µCi (9.25MBq)

This product will be discontinued from our catalog portfolio on January 1, 2017 and will move to our custom iodination portfolio at that time.
List Price : 855.00 USD

ANGIOTENSIN I (human), [125I]Tyr4-, 50µCi (1.85MBq), Species Activity:2200Ci (81.4TBq/mmol)

NEX101 Angiotensin, a protein, causes blood vessels to constrict, and drives blood pressure up. It is part of the renin-angiotensin system, which is a major target for drugs that lower blood pressure. Angiotensin also stimulates the release of aldosterone from the adrenal cortex.
List Price : 1778.00 USD

Goat anti-rabbit IgG, [125I], 250µCi (9.25MBq)

Affinity purified goat anti-rabbit IgG is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method1 and is purified by gel filtration chromatography. This method predominantly labels tyrosine residues.
List Price : 812.00 USD

Angiotensin II, [125I]-Sar1, Ile8], 50µCi

NEX248 [125I]-Sar1-Ile8-Angiotensin II is an angiotensin receptor antagonist which binds to a single class of receptors. [125I]-Sar1-Ile8-Angiotensin II is useful for studying AII receptors when an antagonist ligand is preferred, for receptor localization studies using autoradiographic techniques and for drug screening programs.
List Price : 1976.00 USD

Peptide YY, (Porcine), ([125I]-PYY), 10µCi

NEX240 Synthetic Peptide YY is radioiodinated with no-carrier-added 125I using a modification of the chloramine-T method.
List Price : 872.00 USD

Neurokinin A, ([125I]-Substance K, 10µCi

NEX252 [125I]-NKA is a radioiodinated tachykinin which binds selectively to NK-2 receptors. Typical lots have been tested in a specific NK-2 radioreceptor assay. We do not recommend its use in a radioimmunoassay. The presence of a non-oxidized methionine typically leads to low antibody binding.
List Price : 708.00 USD

INSULIN (porcine), [125I], 10µCi (370kBq), Specific Activity:80-120µCi (2.96-4.44MBq)/µg

NEX104 Insulin (porcine) is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method and purified by ion-exchange column chromatography. This method predominantly labels tyrosine residues.
List Price : 721.00 USD
List Price : 1689.00 USD

LH-RH, [125I]-[D-Trp6]-, 50µCi

NEX365 [125I]-[D-Trp6]-LH-RH will be useful for receptor binding studies in cell lines and tissue cultures.
List Price : 2115.00 USD

Adenosine 3',5'-cyclic Phosphoric Acid, 2`-O-succinyl [125I]-Iodotyrosine Methyl Ester-, 5µCi

Adenosine 3',5'-cyclic Phosphoric Acid, 2'-O-succinyl, [125I]-Iodotyrosine Methyl Ester- Adenosine is an inhibitory neurotransmitter, believed to play a role in promoting sleep and suppressing arousal, with levels increasing with each hour an organism is awake.
List Price : 1042.00 USD
List Price : 875.00 USD

"Iodinated Compounds" 1-50 of 206 Products and Services

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