PerkinElmer

Iodinated Compounds

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We provide 125I- and 131I-labeled compounds, including radioligands specific for receptor/ligand characterization for drug discovery/development and receptor distribution. Because 125I and 131I are gamma emitters, they can be counted directly without requiring scintillant. Additionally, because 125I emits Auger electrons, counting in a liquid scintillation counter is also possible.

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Application
  • Drug Discovery & Development (168)
Concentration
  • 1.0 - 10 mCi/mL (1)
  • 1.12 mCi/mL (2)
  • 1.14 mCi/mL (1)
  • 13.3 MBq/mL (1)
  • 152 µCi/mL (1)
  • 170.1 µCi/mL (2)
  • 171 µCi/mL (1)
  • 171.9 µCi/mL (2)
  • 172.5 µCi/mL (3)
  • 173.9 µCi/mL (1)
  • 182 µCi/mL (2)
  • 2.93 MBq/mL (2)
  • 236 µCi (3)
  • 3.06 MBq/mL (1)
  • 3.22 MBq/mL (1)
  • 33.7 µCi (2)
  • 345 µCi/mL (4)
  • 353 µCi/mL (5)
  • 41.4 µCi/mL (3)
  • 42.5 µCi/mL (1)
  • 45.7 µCi/mL (2)
  • 50 µCi/mL (1)
  • 6.05 MBq/mL (1)
  • 79.2 µCi/mL (2)
  • 83.8 µCi/mL (1)
  • 85.1 µCi/mL (1)
  • 86.3 µCi (1)
  • 87.2 µCi/mL (1)
  • 87.4 µCi/mL (1)
  • 87.6 µCi/mL (1)
  • 87.9 µCi/mL (1)
  • 88.5 µCi/mL (1)
  • 93.2 µCi/mL (2)
  • <1.0 µCi/mL (4)
  • <100 µCi/mL (2)
Detection Method
  • Radiometric (178)
Label Position
  • Nominally Labeled (166)
  • Specifically Labeled (15)
Product Brand Name
  • NEN Radiolabeled Ligands (178)
Radionuclide
  • 125I (180)
Receptor Type
  • 5-Hydroxytryptamine (2)
  • Adenosine (2)
  • Adrenoceptors (4)
  • Angiotensin (5)
  • Apelin (3)
  • Bombesin (4)
  • Calcitonin (3)
  • Calcium (4)
  • Chemokine (12)
  • Cholecystokinin (2)
  • Corticotropin-Releasing Factor (3)
  • Dopamine (2)
  • Endothelin (3)
  • Epidermal Growth Factor (4)
  • Ghrelin (2)
  • Glucagon (6)
  • Gonadotropin-releasing Hormone (2)
  • Growth Hormone (2)
  • Histamine (1)
  • Insulin (5)
  • Insulin-like Growth Factor (2)
  • Interleukin (4)
  • Melanin-Concentrating Hormone (2)
  • Melanocortin (4)
  • Melatonin (3)
  • Motilin (2)
  • Neuropeptide Y (6)
  • Neurotensin (2)
  • Nicotinic (7)
  • Orexin (2)
  • Oxytocin (3)
  • Peptide P518 (2)
  • Platelet-Derived Growth Factor (1)
  • Potassium (2)
  • SK channels (2)
  • Somatostatin (4)
  • Tachykinin (6)
  • Thyroid Hormone (6)
  • Transforming Growth Factor (3)
  • Urotensin (2)
  • Vasoactive Intestinal Peptide (4)
  • Vasopressin (4)
Therapeutic Area
  • Angiogenesis (12)
  • Cancer (22)
  • Cardiovascular (41)
  • CNS & Neurologic (84)
  • Diabetes (14)
  • Gastrointestinal (25)
  • Inflammation (60)
  • Metabolic Disorders (45)
  • Obesity (11)
  • Pain (22)
Volume
  • 0-50 (19)
  • 51-100 (1)
  • 201-250 (1)

"Iodinated Compounds" 1-50 of 181 Products and Services

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Calcitonin [Tyr22] (salmon), [125I] 10 µCi

NEX423 [125I]-Calcitonin, [Tyr22] (s) is suitable for the use in radioimmunoassay as well as in the radio-receptor assay.
List Price : 846.00 USD

[125I]- Epidermal Growth Factor (h, r), 25 µCi

NEX428 Epidermal Growth Factor is radioiodinated with no carrier added 125I using a lactoperoxidase procedure and is purified by reversed phase HPLC.
List Price : 1523.00 USD

Thyroxine, ([125I]-T4), L-[125I]-, 500µCi (18.5MBq), Specific Activity: 135-165µCi (5.00-6.11MBq)/µg

NEX111 L-3,5-Diiodothyronine is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method and is purified by reversed phase HPLC.
List Price : 1730.00 USD

IL-6 (human, recombinant), [125I], 5µCi

NEX269 Interleukin-6 (IL-6) is a protein that in humans is encoded by the IL6 gene. IL-6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation.
List Price : 1173.00 USD
List Price : 1881.00 USD

SDF-1α (human, recombinant), [125I]-, 5µCi

NEX346 SDF-1 a acts at the CXCR4 (fusin or LESTR) receptor. 125I-SDF-1 a competes with SDF-1 a in CXCR4 receptor binding assays.
List Price : 708.00 USD
List Price : 2208.00 USD

α-Bungarotoxin, [125I]-Tyr54-, 50µCi (1.85MBq)

α-bungarotoxin extracted from venom of the Taiwanese banded krait (Bungarus multicinctus) binds the nicotinic acetylcholine receptor found at the neuromuscular junction and the 7 nicotinic acetylcholine receptor in the brain.
List Price : 539.00 USD
List Price : 1197.00 USD

MIP-1α (human, recombinant), [125I], 25µCi

NEX298 [125I]-MIP-1α is useful in RIA, receptor studies and crosslinking experiments in the research into immune regulation.
List Price : 2318.00 USD

Apamin [125I]His18-NH2, 25µCi

NEX242 [125I]-Apamin is a K+ channel antagonist and can be used in the detection and quantification of K+ channel receptors. [125I]-Apamin has been used in receptor binding assays and in autoradiography.
List Price : 851.00 USD
List Price : 2120.00 USD

CGRP (human), [125I]-, 50µCi

NEX354 Human CGRP binds to human CGRP receptors in the central nervous system and peripheral nervous system. [125I]-CGRP (human) will be useful in the characterization of CGRP receptors.
List Price : 1840.00 USD

Goat anti-rabbit IgG, [125I], 250µCi (9.25MBq)

Affinity purified goat anti-rabbit IgG is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method1 and is purified by gel filtration chromatography. This method predominantly labels tyrosine residues.
List Price : 893.00 USD

ACTH (1-39) 23Tyr [125I], 10 µCi

[125I]ACTH is lyophilized from an acetic acid solution (0.1%) containing bovine serum albumin (0.25%), lactose (5%), L-cysteine hydrochloride (0.1%) and aprotinin (0.3TIU/ml).
List Price : 1118.00 USD

Insulin (human, recombinant), [125I], 10 µCi

[125I]-Insulin (h) is suitable for the use in radioimmunoassay as well as receptor binding assay. [125I]-Insulin (h) is radioiodinated with no carrier added 125I using the LPO iodination procedure and is purified by reversed phase HPLC.
List Price : 1033.00 USD

Somatostatin-14 (human, recombinant), Receptor Grade, 50µCi

NEX446 Tyr11 Somatostatin-14 is radioiodinated with no-carrier-added 125I using amodified lactoperoxidase procedure and is purified by reversed phase HPLC. This method predominantly labels tyrosine residues.
List Price : 2083.00 USD

Lysergic Acid Diethylamide, 2-[125I]iodo-(+), 10µCi

NEX199 Preparations have been shown to be active in binding to the serotonin receptors. LSD affects a large number of the G protein coupled receptors, including all dopamine receptor subtypes, and all adrenoreceptor subtypes, as well as many others. LSD binds to most serotonin receptor subtypes except for 5-HT3 and 5-HT4.
List Price : 838.00 USD

α-Bungarotoxin, [125I]-Tyr54-, 250µCi (9.25MBq)

α-bungarotoxin extracted from venom of the Taiwanese banded krait (Bungarus multicinctus) binds the nicotinic acetylcholine receptor found at the neuromuscular junction and the 7 nicotinic acetylcholine receptor in the brain.
List Price : 1232.00 USD
List Price : 2557.00 USD

α-Bungarotoxin, [125I]-Tyr54-, High Specific Activity, 250 µCi

α-bungarotoxin extracted from venom of the Taiwanese banded krait (Bungarus multicinctus) binds the nicotinic acetylcholine receptor found at the neuromuscular junction and the 7 nicotinic acetylcholine receptor in the brain.
List Price : 1931.00 USD

Peptide YY (Human), ([125I]-PYY), 10µCi

NEX341 [125I]-Peptide YY (human) will be useful for characterizing Peptide YY receptors.
List Price : 849.00 USD

Neurokinin A, ([125I]-Substance K, 50µCi

NEX252 [125I]-NKA is a radioiodinated tachykinin which binds selectively to NK-2 receptors. Typical lots have been tested in a specific NK-2 radioreceptor assay. We do not recommend its use in a radioimmunoassay. The presence of a non-oxidized methionine typically leads to low antibody binding.
List Price : 1872.00 USD

Iodoaminopotentidine, [125I], 25 µCi

NEX431 [125I]-Aminopotentidine has been shown to work in receptor binding and autoradiography and is an antagonist for histamine (H2) receptors.
List Price : 1839.00 USD
List Price : 3312.00 USD

Peptide YY, (Porcine), ([125I]-PYY), 50µCi

NEX240 Synthetic Peptide YY is radioiodinated with no-carrier-added 125I using a modification of the chloramine-T method.
List Price : 2215.00 USD

Bombesin, [125I]Tyr4-, 10µCi (370kBq)

NEX258 [125I]-Bombesin will be useful as a tracer in RIAs for bombesin like peptides, and as a high specific activity ligand in receptor studies.
List Price : 992.00 USD

Angiotensin II, [125I]-Sar1, Ile8], 50µCi

NEX248 [125I]-Sar1-Ile8-Angiotensin II is an angiotensin receptor antagonist which binds to a single class of receptors. [125I]-Sar1-Ile8-Angiotensin II is useful for studying AII receptors when an antagonist ligand is preferred, for receptor localization studies using autoradiographic techniques and for drug screening programs.
List Price : 2174.00 USD

Substance P, [125I]Tyr8], 10µCi

Substance P, [125I]Tyr8] is radioiodinated with no carrier added 125I by a lactoperoxidase procedure and is purified by reversed phase HPLC.
List Price : 1092.00 USD

Thyroxine, ([125I]-T4), L-[125I]-, 100µCi (3.7MBq), Specific Activity: 135-165µCi (5.00-6.11MBq)/µg

NEX111 L-3,5-Diiodothyronine is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method and is purified by reversed phase HPLC.
List Price : 620.00 USD

α-MSH, Nle4, D-Phe7, [125I], 10µCi

NEX352 α-MSH is a highly potent and metabolically stable analog of α-MSH.7 [125I]-[Nle4, D-Phe7]-α-MSH can be used to label all subtypes of melanocortin receptors with high affinity and low non-specific binding.
List Price : 987.00 USD

ProTx-II (tarantula), [125I], 10µCi

[125I]-ProTx-II (tarantula) NEX450010UC. This product extends offerings for sodium Ion channels, the disease state is Pain. ProTx-II selectively alters the rate of activation for voltage-gated sodium channels Nav1.7. Related products Sodium Channel and Potassium Channel
List Price : 995.00 USD

Apamin [125I]His18-NH2, 50µCi

NEX242 [125I]-Apamin is a K+ channel antagonist and can be used in the detection and quantification of K+ channel receptors. [125I]-Apamin has been used in receptor binding assays and in autoradiography.
List Price : 1415.00 USD

Insulin-like Growth Factor-I (human, recombinant), 5µCi

NEX241 IGF-1 is produced primarily by the liver as an endocrine hormone as well as in target tissues in a paracrine/autocrine fashion. Production is stimulated by growth hormone (GH) and can be retarded by undernutrition, growth hormone insensitivity, lack of growth hormone receptors, or failures of the downstream signalling pathway post GH receptor including SHP2 and STAT5B.
List Price : 643.00 USD

2`-Deoxycytidine-5`-triphosphate, 5-[125I]iodo-, Tetraammonium Salt, 100µCi (3.7MBq)

Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that is used whenever DNA is synthesized, such as in the polymerase chain reaction. 125I dCTP may be used to produce cDNA transcripts of viral or mRNA.
List Price : 1044.00 USD
List Price : 962.00 USD

ACTH (1-39) 23Tyr [125I], 50 µCi

[125I]ACTH is lyophilized from an acetic acid solution (0.1%) containing bovine serum albumin (0.25%), lactose (5%), L-cysteine hydrochloride (0.1%) and aprotinin (0.3TIU/ml).
List Price : 4474.00 USD

Somatostatin-14 (human, recombinant), Receptor Grade, 10 µCi

NEX446 Tyr11 Somatostatin-14 is radioiodinated with no-carrier-added 125I using amodified lactoperoxidase procedure and is purified by reversed phase HPLC. This method predominantly labels tyrosine residues.
List Price : 859.00 USD

[125I]- Epidermal Growth Factor (h, r), 5 µCi

NEX428 Epidermal Growth Factor is radioiodinated with no carrier added 125I using a lactoperoxidase procedure and is purified by reversed phase HPLC.
List Price : 690.00 USD
List Price : 1721.00 USD
List Price : 739.00 USD

Lysergic Acid Diethylamide, 2-[125I]iodo-(+), 50µCi

NEX199 Preparations have been shown to be active in binding to the serotonin receptors. LSD affects a large number of the G protein coupled receptors, including all dopamine receptor subtypes, and all adrenoreceptor subtypes, as well as many others. LSD binds to most serotonin receptor subtypes except for 5-HT3 and 5-HT4.
List Price : 2013.00 USD

CGP 42112A, [125I]-, 25µCi

NEX324 Extremely high selectivity makes [125I]-CGP 42112A very useful for competitive binding assays, isolation of receptors, and autoradiography.
List Price : 1669.00 USD
List Price : 1892.00 USD
List Price : 882.00 USD

IP-10 (human, recombinant), [125I]-, Bolton-Hunter Labeled, 5µCi

NEX348 IP-10 acts at the CXCR3 receptor and attracts T cells, particularly activated T cells.
List Price : 708.00 USD

RTI-55, [125I]-, 25µCi (925kBq)

NEX272 [125I]-RTI-55 is an excellent radioligand for the study of the dopamine transporter sites using either tissue homogenates or autoradiographic methods--especially in regions of low receptor density.
List Price : 861.00 USD
List Price : 1098.00 USD

"Iodinated Compounds" 1-50 of 181 Products and Services

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