PerkinElmer

Iodinated Compounds

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We provide 125I- and 131I-labeled compounds, including radioligands specific for receptor/ligand characterization for drug discovery/development and receptor distribution. Because 125I and 131I are gamma emitters, they can be counted directly without requiring scintillant. Additionally, because 125I emits Auger electrons, counting in a liquid scintillation counter is also possible.

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Application
  • Drug Discovery & Development (168)
Concentration
  • 1.0 - 10 mCi/mL (1)
  • 1.12 mCi/mL (2)
  • 1.14 mCi/mL (1)
  • 13.3 MBq/mL (1)
  • 152 µCi/mL (1)
  • 170.1 µCi/mL (2)
  • 171 µCi/mL (1)
  • 171.9 µCi/mL (2)
  • 172.5 µCi/mL (3)
  • 173.9 µCi/mL (1)
  • 182 µCi/mL (2)
  • 2.93 MBq/mL (2)
  • 236 µCi (3)
  • 3.06 MBq/mL (1)
  • 3.22 MBq/mL (1)
  • 33.7 µCi (2)
  • 345 µCi/mL (4)
  • 353 µCi/mL (5)
  • 41.4 µCi/mL (3)
  • 42.5 µCi/mL (1)
  • 45.7 µCi/mL (2)
  • 50 µCi/mL (1)
  • 6.05 MBq/mL (1)
  • 79.2 µCi/mL (2)
  • 83.8 µCi/mL (1)
  • 85.1 µCi/mL (1)
  • 86.3 µCi (1)
  • 87.2 µCi/mL (1)
  • 87.4 µCi/mL (1)
  • 87.6 µCi/mL (1)
  • 87.9 µCi/mL (1)
  • 88.5 µCi/mL (1)
  • 93.2 µCi/mL (2)
  • <1.0 µCi/mL (4)
  • <100 µCi/mL (2)
Detection Method
  • Radiometric (178)
Label Position
  • Nominally Labeled (166)
  • Specifically Labeled (15)
Product Brand Name
  • NEN Radiolabeled Ligands (178)
Radionuclide
  • 125I (180)
Receptor Type
  • 5-Hydroxytryptamine (2)
  • Adenosine (2)
  • Adrenoceptors (4)
  • Angiotensin (5)
  • Apelin (3)
  • Bombesin (4)
  • Calcitonin (3)
  • Calcium (4)
  • Chemokine (12)
  • Cholecystokinin (2)
  • Corticotropin-Releasing Factor (3)
  • Dopamine (2)
  • Endothelin (3)
  • Epidermal Growth Factor (4)
  • Ghrelin (2)
  • Glucagon (6)
  • Gonadotropin-releasing Hormone (2)
  • Growth Hormone (2)
  • Histamine (1)
  • Insulin (5)
  • Insulin-like Growth Factor (2)
  • Interleukin (4)
  • Melanin-Concentrating Hormone (2)
  • Melanocortin (4)
  • Melatonin (3)
  • Motilin (2)
  • Neuropeptide Y (6)
  • Neurotensin (2)
  • Nicotinic (7)
  • Orexin (2)
  • Oxytocin (3)
  • Peptide P518 (2)
  • Platelet-Derived Growth Factor (1)
  • Potassium (2)
  • SK channels (2)
  • Somatostatin (4)
  • Tachykinin (6)
  • Thyroid Hormone (6)
  • Transforming Growth Factor (3)
  • Urotensin (2)
  • Vasoactive Intestinal Peptide (4)
  • Vasopressin (4)
Therapeutic Area
  • Angiogenesis (12)
  • Cancer (22)
  • Cardiovascular (41)
  • CNS & Neurologic (84)
  • Diabetes (14)
  • Gastrointestinal (25)
  • Inflammation (60)
  • Metabolic Disorders (45)
  • Obesity (11)
  • Pain (22)
Volume
  • 0-50 (82)
  • 51-100 (1)
  • 201-250 (2)

"Iodinated Compounds" 1-50 of 181 Products and Services

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List Price : 1033.00 USD
List Price : 1685.00 USD

Iodo-Melatonin, 2-[125I], 250µCi

NEX236 2-[125I]-iodomelatonin has been used to identify, characterize and localize melatonin binding sites in the brain and peripheral tissues.
List Price : 2379.00 USD
List Price : 1731.00 USD

Somatostatin, [125I]Tyr11, 50µCi

NEX389 Somatostatin is a cyclic neuropeptide found in the brain, pancreas and hypothalamus and inhibits the release of growth hormone. [125I ] Tyr11 somatostatin binds to the receptors on RINm5F insolinoma cells with high affinity and inhibits the secretion of insulin from pancreatic b cells.
List Price : 2007.00 USD

Bombesin (6-14), D-Tyr6[125I], 25µCi

NEX377 [D-Tyr6[125I]-, βAla11, Phe13, Nle14]-Bombesin (6-14) is a high affinity agonist to the human Orphan Bombesin Receptor Subtype 3 (hBRS-3).
[D-Tyr6[125I]-, bAla11, Phe13, Nle14]-Bombesin (6-14) will be a useful tool to study the pharmacology of this orphan receptor as well as the natural ligand for this receptor.
List Price : 2229.00 USD
List Price : 1881.00 USD

[125I]Tyr0-Corticotropin Releasing Factor (ovine), 10 µCi

NEX217 Corticotropin-releasing hormone (CRH), originally named corticotropin-releasing factor (CRF), and also called corticoliberin, is a polypeptide hormone and neurotransmitter involved in the stress response.
List Price : 1140.00 USD

Epidermal Growth Factor (Murine), [125I]-,50µCi

Epidermal growth factor or EGF is a growth factor that plays an important role in the regulation of cell growth, proliferation, and differentiation by binding to its receptor EGFR.
List Price : 1943.00 USD

SDF-1α (human, recombinant), [125I]-, 5µCi

NEX346 SDF-1 a acts at the CXCR4 (fusin or LESTR) receptor. 125I-SDF-1 a competes with SDF-1 a in CXCR4 receptor binding assays.
List Price : 708.00 USD
List Price : 882.00 USD

Thyroxine, ([125I]-T4), L-[125I]-, 250µCi (9.25MBq), Specific Activity: 135-165µCi (5.00-6.11MBq)/µg

NEX111 L-3,5-Diiodothyronine is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method and is purified by reversed phase HPLC.
List Price : 925.00 USD
List Price : 1731.00 USD

Substance P, [125I]Tyr8], 50µCi

Substance P, [125I]Tyr8] is radioiodinated with no carrier added 125I by a lactoperoxidase procedure and is purified by reversed phase HPLC.
List Price : 2356.00 USD
List Price : 1197.00 USD

Iodoaminopotentidine, [125I], 25 µCi

NEX431 [125I]-Aminopotentidine has been shown to work in receptor binding and autoradiography and is an antagonist for histamine (H2) receptors.
List Price : 1839.00 USD
List Price : 1197.00 USD

Thyroxine, ([125I]-T4), L-[125I]-, 500µCi (18.5MBq), Specific Activity: 135-165µCi (5.00-6.11MBq)/µg

NEX111 L-3,5-Diiodothyronine is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method and is purified by reversed phase HPLC.
List Price : 1730.00 USD

Endothelin-1 (human, porcine), [125I]Tyr13, 5µCi

NEX259 [125I]-ET-1 will be useful as a tracer in RIA's for endothelin, and as a high specific activity ligand in receptor studies encompassing the areas of vasoconstriction and stroke, smooth muscle and renal function, and in the study of neurotransmitters in the CNS.
List Price : 869.00 USD

Adenosine 3',5'-cyclic Phosphoric Acid, 2`-O-succinyl [125I]-Iodotyrosine Methyl Ester-, 5µCi

Adenosine 3',5'-cyclic Phosphoric Acid, 2'-O-succinyl, [125I]-Iodotyrosine Methyl Ester- Adenosine is an inhibitory neurotransmitter, believed to play a role in promoting sleep and suppressing arousal, with levels increasing with each hour an organism is awake.
List Price : 1146.00 USD

IP-10 (human, recombinant), [125I]-, Bolton-Hunter Labeled, 5µCi

NEX348 IP-10 acts at the CXCR3 receptor and attracts T cells, particularly activated T cells.
List Price : 708.00 USD

Angiotensin II, [125I]-Sar1, Ile8], 50µCi

NEX248 [125I]-Sar1-Ile8-Angiotensin II is an angiotensin receptor antagonist which binds to a single class of receptors. [125I]-Sar1-Ile8-Angiotensin II is useful for studying AII receptors when an antagonist ligand is preferred, for receptor localization studies using autoradiographic techniques and for drug screening programs.
List Price : 2174.00 USD

Lysergic Acid Diethylamide, 2-[125I]iodo-(+), 50µCi

NEX199 Preparations have been shown to be active in binding to the serotonin receptors. LSD affects a large number of the G protein coupled receptors, including all dopamine receptor subtypes, and all adrenoreceptor subtypes, as well as many others. LSD binds to most serotonin receptor subtypes except for 5-HT3 and 5-HT4.
List Price : 2013.00 USD

Bombesin, [125I]Tyr4-, 10µCi (370kBq)

NEX258 [125I]-Bombesin will be useful as a tracer in RIAs for bombesin like peptides, and as a high specific activity ligand in receptor studies.
List Price : 992.00 USD

Substance P, [125I]Tyr8], 10µCi

Substance P, [125I]Tyr8] is radioiodinated with no carrier added 125I by a lactoperoxidase procedure and is purified by reversed phase HPLC.
List Price : 1092.00 USD

Epidermal Growth Factor (Murine), [125I]-,10µCi

Epidermal growth factor or EGF is a growth factor that plays an important role in the regulation of cell growth, proliferation, and differentiation by binding to its receptor EGFR.
List Price : 761.00 USD
List Price : 739.00 USD
List Price : 933.00 USD

Interleukin-1β (human, recombinant), [125I], 5µCi

NEX232 Interleukin-1 (IL-1) refers to a group of three polypeptides (interleukin-1 alpha (IL-1α), interleukin-1 beta (IL-1β) and interleukin-1 receptor antagonist (IL-1Ra)), that play a central role in the regulation of immune and inflammatory responses.

IL-1β is a pro-inflammatory cytokine involved in immune defense against infection.

List Price : 925.00 USD

ProTx-II (tarantula), [125I], 50µCi

[125I]-ProTx-II (tarantula) NEX450010UC. This product extends offerings for sodium Ion channels, the disease state is Pain. ProTx-II selectively alters the rate of activation for voltage-gated sodium channels Nav1.7. Related products Sodium Channel and Potassium Channel
List Price : 3162.00 USD
List Price : 2208.00 USD

MCP-1,[125I]- labeled, Bolton-Hunter Labeled, 25µCi

NEX313 Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). It is found at the site of tooth eruption and bone degradation. In the bone, CCL2 is expressed by mature osteoclasts and osteoblasts and is under the control of nuclear factor κB (NFκB).
List Price : 1646.00 USD

Peptide YY, (Porcine), ([125I]-PYY), 50µCi

NEX240 Synthetic Peptide YY is radioiodinated with no-carrier-added 125I using a modification of the chloramine-T method.
List Price : 2215.00 USD

α-Bungarotoxin, [125I]-Tyr54-, 50µCi (1.85MBq)

α-bungarotoxin extracted from venom of the Taiwanese banded krait (Bungarus multicinctus) binds the nicotinic acetylcholine receptor found at the neuromuscular junction and the 7 nicotinic acetylcholine receptor in the brain.
List Price : 539.00 USD

Apamin [125I]His18-NH2, 25µCi

NEX242 [125I]-Apamin is a K+ channel antagonist and can be used in the detection and quantification of K+ channel receptors. [125I]-Apamin has been used in receptor binding assays and in autoradiography.
List Price : 851.00 USD

GLP-1 (7-36), [125I]-, 50µCi (1.85MBq)

NEX308 Glucagon-like peptide-1 (GLP-1) is derived from the transcription product of the proglucagon gene. The major source of GLP-1 in the body is the intestinal L cell that secretes GLP-1 as a gut hormone. The biologically active forms of GLP-1 are: GLP-1-(7-37) and GLP-1-(7-36)NH2.
List Price : 2118.00 USD
List Price : 2251.00 USD

Adenosine 3',5'-cyclic Phosphoric Acid, 2`-O-succinyl [125I]-Iodotyrosine Methyl Ester-, 50µCi

Adenosine 3',5'-cyclic Phosphoric Acid, 2'-O-succinyl, [125I]-Iodotyrosine Methyl Ester- Adenosine is an inhibitory neurotransmitter, believed to play a role in promoting sleep and suppressing arousal, with levels increasing with each hour an organism is awake.
List Price : 4404.00 USD

Endothelin-1 (human, porcine), [125I]Tyr13, 50µCi

NEX259 [125I]-ET-1 will be useful as a tracer in RIA's for endothelin, and as a high specific activity ligand in receptor studies encompassing the areas of vasoconstriction and stroke, smooth muscle and renal function, and in the study of neurotransmitters in the CNS.
List Price : 2390.00 USD

Peptide YY (Human), ([125I]-PYY), 10µCi

NEX341 [125I]-Peptide YY (human) will be useful for characterizing Peptide YY receptors.
List Price : 849.00 USD

ANGIOTENSIN I (human), [125I]Tyr4-, 10µCi (370kBq), Species Activity:2200Ci (81.4TBq/mmol)

NEX101 Angiotensin, a protein, causes blood vessels to constrict, and drives blood pressure up. It is part of the renin-angiotensin system, which is a major target for drugs that lower blood pressure. Angiotensin also stimulates the release of aldosterone from the adrenal cortex.
List Price : 816.00 USD
List Price : 882.00 USD

Insulin (porcine), Receptor Grade, [125I]TyrA14], 50µCi

[125I]TyrA14 Insulin has been proven to be active in a receptor binding assay using cultured human fibroblasts as described.8 It may also be used in radioimmunoassay.
List Price : 2143.00 USD
List Price : 980.00 USD

IP-10 (human, recombinant), [125I]-, Bolton-Hunter Labeled, 25µCi

NEX348 IP-10 acts at the CXCR3 receptor and attracts T cells, particularly activated T cells.
List Price : 1718.00 USD

ACTH (1-39) 23Tyr [125I], 50 µCi

[125I]ACTH is lyophilized from an acetic acid solution (0.1%) containing bovine serum albumin (0.25%), lactose (5%), L-cysteine hydrochloride (0.1%) and aprotinin (0.3TIU/ml).
List Price : 4474.00 USD

[125I]- Epidermal Growth Factor (h, r), 25 µCi

NEX428 Epidermal Growth Factor is radioiodinated with no carrier added 125I using a lactoperoxidase procedure and is purified by reversed phase HPLC.
List Price : 1523.00 USD

Apamin [125I]His18-NH2, 50µCi

NEX242 [125I]-Apamin is a K+ channel antagonist and can be used in the detection and quantification of K+ channel receptors. [125I]-Apamin has been used in receptor binding assays and in autoradiography.
List Price : 1415.00 USD

"Iodinated Compounds" 1-50 of 181 Products and Services

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