PerkinElmer

Iodinated Compounds

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We provide 125I- and 131I-labeled compounds, including radioligands specific for receptor/ligand characterization for drug discovery/development and receptor distribution. Because 125I and 131I are gamma emitters, they can be counted directly without requiring scintillant. Additionally, because 125I emits Auger electrons, counting in a liquid scintillation counter is also possible.

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Application
  • Drug Discovery & Development (168)
Concentration
  • 1.0 - 10 mCi/mL (1)
  • 1.12 mCi/mL (2)
  • 1.14 mCi/mL (1)
  • 13.3 MBq/mL (1)
  • 152 µCi/mL (1)
  • 170.1 µCi/mL (2)
  • 171 µCi/mL (1)
  • 171.9 µCi/mL (2)
  • 172.5 µCi/mL (3)
  • 173.9 µCi/mL (1)
  • 182 µCi/mL (2)
  • 2.93 MBq/mL (2)
  • 236 µCi (3)
  • 3.06 MBq/mL (1)
  • 3.22 MBq/mL (1)
  • 33.7 µCi (2)
  • 345 µCi/mL (4)
  • 353 µCi/mL (5)
  • 41.4 µCi/mL (3)
  • 42.5 µCi/mL (1)
  • 45.7 µCi/mL (2)
  • 50 µCi/mL (1)
  • 6.05 MBq/mL (1)
  • 79.2 µCi/mL (2)
  • 83.8 µCi/mL (1)
  • 85.1 µCi/mL (1)
  • 86.3 µCi (1)
  • 87.2 µCi/mL (1)
  • 87.4 µCi/mL (1)
  • 87.6 µCi/mL (1)
  • 87.9 µCi/mL (1)
  • 88.5 µCi/mL (1)
  • 93.2 µCi/mL (2)
  • <1.0 µCi/mL (4)
  • <100 µCi/mL (2)
Detection Method
  • Radiometric (178)
Label Position
  • Nominally Labeled (166)
  • Specifically Labeled (15)
Product Brand Name
  • NEN Radiolabeled Ligands (178)
Radionuclide
  • 125I (180)
Receptor Type
  • 5-Hydroxytryptamine (2)
  • Adenosine (2)
  • Adrenoceptors (4)
  • Angiotensin (5)
  • Apelin (3)
  • Bombesin (4)
  • Calcitonin (3)
  • Calcium (4)
  • Chemokine (12)
  • Cholecystokinin (2)
  • Corticotropin-Releasing Factor (3)
  • Dopamine (2)
  • Endothelin (3)
  • Epidermal Growth Factor (4)
  • Ghrelin (2)
  • Glucagon (6)
  • Gonadotropin-releasing Hormone (2)
  • Growth Hormone (2)
  • Histamine (1)
  • Insulin (5)
  • Insulin-like Growth Factor (2)
  • Interleukin (4)
  • Melanin-Concentrating Hormone (2)
  • Melanocortin (4)
  • Melatonin (3)
  • Motilin (2)
  • Neuropeptide Y (6)
  • Neurotensin (2)
  • Nicotinic (7)
  • Orexin (2)
  • Oxytocin (3)
  • Peptide P518 (2)
  • Platelet-Derived Growth Factor (1)
  • Potassium (2)
  • SK channels (2)
  • Somatostatin (4)
  • Tachykinin (6)
  • Thyroid Hormone (6)
  • Transforming Growth Factor (3)
  • Urotensin (2)
  • Vasoactive Intestinal Peptide (4)
  • Vasopressin (4)
Therapeutic Area
  • Angiogenesis (12)
  • Cancer (22)
  • Cardiovascular (41)
  • CNS & Neurologic (84)
  • Diabetes (14)
  • Gastrointestinal (25)
  • Inflammation (60)
  • Metabolic Disorders (45)
  • Obesity (11)
  • Pain (22)
Volume
  • 0-50 (19)
  • 51-100 (1)
  • 201-250 (1)

"Iodinated Compounds" 1-50 of 181 Products and Services

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Lysergic Acid Diethylamide, 2-[125I]iodo-(+), 250µCi

NEX199 Preparations have been shown to be active in binding to the serotonin receptors. LSD affects a large number of the G protein coupled receptors, including all dopamine receptor subtypes, and all adrenoreceptor subtypes, as well as many others. LSD binds to most serotonin receptor subtypes except for 5-HT3 and 5-HT4.
List Price : 4574.00 USD

Lysergic Acid Diethylamide, 2-[125I]iodo-(+), 10µCi

NEX199 Preparations have been shown to be active in binding to the serotonin receptors. LSD affects a large number of the G protein coupled receptors, including all dopamine receptor subtypes, and all adrenoreceptor subtypes, as well as many others. LSD binds to most serotonin receptor subtypes except for 5-HT3 and 5-HT4.
List Price : 838.00 USD
List Price : 1197.00 USD

Bombesin (6-14), D-Tyr6[125I], 25µCi

NEX377 [D-Tyr6[125I]-, βAla11, Phe13, Nle14]-Bombesin (6-14) is a high affinity agonist to the human Orphan Bombesin Receptor Subtype 3 (hBRS-3).
[D-Tyr6[125I]-, bAla11, Phe13, Nle14]-Bombesin (6-14) will be a useful tool to study the pharmacology of this orphan receptor as well as the natural ligand for this receptor.
List Price : 2229.00 USD
List Price : 1685.00 USD
List Price : 2557.00 USD
List Price : 1033.00 USD

Lysergic Acid Diethylamide, 2-[125I]iodo-(+), 50µCi

NEX199 Preparations have been shown to be active in binding to the serotonin receptors. LSD affects a large number of the G protein coupled receptors, including all dopamine receptor subtypes, and all adrenoreceptor subtypes, as well as many others. LSD binds to most serotonin receptor subtypes except for 5-HT3 and 5-HT4.
List Price : 2013.00 USD

Cholecystokinin Octapeptide, [125I]-, Bolton-Hunter Labeled, 10µCi

NEX203 CCK-8 mediates a number of physiological processes, including digestion and satiety. It is located in the small intestine, and detects the presence of fat in the chyme. As a neuropeptide, CCK mediates satiety by acting on the CCK receptors distributed widely throughout the central nervous system.
List Price : 979.00 USD

AB-MECA, [125I]-(4-Amino-3-[125I]iodobenzyl-5`-N-)-, 50µCi

AB-MECA is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method and is purified by reversed phase HPLC.
List Price : 2208.00 USD

HUMAN GROWTH HORMONE, [125I], 10 µCi

Human growth hormone stimulates growth, cell reproduction and regeneration in animals. HGH functions to regulate body composition, fluid homeostasis, glucose and lipid metabolism, skeletal muscle and bone growth.<
List Price : 838.00 USD

Insulin (porcine), Receptor Grade, [125I]TyrA14], 50µCi

[125I]TyrA14 Insulin has been proven to be active in a receptor binding assay using cultured human fibroblasts as described.8 It may also be used in radioimmunoassay.
List Price : 2143.00 USD
List Price : 2251.00 USD

RTI-55, [125I]-, 250µCi (9.25MBq)

NEX272 [125I]-RTI-55 is an excellent radioligand for the study of the dopamine transporter sites using either tissue homogenates or autoradiographic methods--especially in regions of low receptor density.
List Price : 1715.00 USD

Angiotensin II, [125I]-Sar1, Ile8], 50µCi

NEX248 [125I]-Sar1-Ile8-Angiotensin II is an angiotensin receptor antagonist which binds to a single class of receptors. [125I]-Sar1-Ile8-Angiotensin II is useful for studying AII receptors when an antagonist ligand is preferred, for receptor localization studies using autoradiographic techniques and for drug screening programs.
List Price : 2174.00 USD
List Price : 1046.00 USD
List Price : 739.00 USD

INSULIN (porcine), [125I], 10µCi (370kBq), Specific Activity:80-120µCi (2.96-4.44MBq)/µg

NEX104 Insulin (porcine) is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method and purified by ion-exchange column chromatography. This method predominantly labels tyrosine residues.
List Price : 794.00 USD

Glucagon, Receptor Grade, [125I]-, 50µCi

NEX207 Glucagon is radioiodinated with no carrier added 125I by a lactoperoxidase procedure and is purified by reversed phase HPLC. [125I]-Glucagon consists of an approximately 1:1 ratio of Tyr10 and Tyr13 labeled glucagon. Met27 is in its native thioether form.
List Price : 2067.00 USD

Epidermal Growth Factor (Murine), [125I]-,50µCi

Epidermal growth factor or EGF is a growth factor that plays an important role in the regulation of cell growth, proliferation, and differentiation by binding to its receptor EGFR.
List Price : 1943.00 USD

ANGIOTENSIN II (human), [125I]-Tyr4 -50 μCi

NEX105 Packaged lyophilized from phosphate-buffered saline containing glycine, BSA and Trasylol®
List Price : 1935.00 USD

HUMAN GROWTH HORMONE, [125I], 50 µCi

Human growth hormone stimulates growth, cell reproduction and regeneration in animals. HGH functions to regulate body composition, fluid homeostasis, glucose and lipid metabolism, skeletal muscle and bone growth.<
List Price : 2246.00 USD

LH-RH, [125I]-[D-Trp6]-, 50µCi

NEX365 [125I]-[D-Trp6]-LH-RH will be useful for receptor binding studies in cell lines and tissue cultures.
List Price : 2326.00 USD
List Price : 1892.00 USD

Iodoaminopotentidine, [125I], 10 µCi

NEX431 [125I]-Aminopotentidine has been shown to work in receptor binding and autoradiography and is an antagonist for histamine (H2) receptors.
List Price : 815.00 USD

Somatostatin-14 (human, recombinant), Receptor Grade, 10 µCi

NEX446 Tyr11 Somatostatin-14 is radioiodinated with no-carrier-added 125I using amodified lactoperoxidase procedure and is purified by reversed phase HPLC. This method predominantly labels tyrosine residues.
List Price : 859.00 USD

Insulin (porcine), Receptor Grade, [125I]TyrA14], 10µCi

[125I]TyrA14 Insulin has been proven to be active in a receptor binding assay using cultured human fibroblasts as described.8 It may also be used in radioimmunoassay.
List Price : 1098.00 USD
List Price : 2208.00 USD

Glucagon, Receptor Grade, [125I]-, 10µCi

NEX207 Glucagon is radioiodinated with no carrier added 125I by a lactoperoxidase procedure and is purified by reversed phase HPLC. [125I]-Glucagon consists of an approximately 1:1 ratio of Tyr10 and Tyr13 labeled glucagon. Met27 is in its native thioether form.
List Price : 979.00 USD

MIP-1α (human, recombinant), [125I], 25µCi

NEX298 [125I]-MIP-1α is useful in RIA, receptor studies and crosslinking experiments in the research into immune regulation.
List Price : 2318.00 USD

AB-MECA, [125I]-(4-Amino-3-[125I]iodobenzyl-5`-N-)-, 10µCi

AB-MECA is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method and is purified by reversed phase HPLC.
List Price : 1133.00 USD

Neurokinin A, ([125I]-Substance K, 10µCi

NEX252 [125I]-NKA is a radioiodinated tachykinin which binds selectively to NK-2 receptors. Typical lots have been tested in a specific NK-2 radioreceptor assay. We do not recommend its use in a radioimmunoassay. The presence of a non-oxidized methionine typically leads to low antibody binding.
List Price : 779.00 USD

Apamin [125I]His18-NH2, 50µCi

NEX242 [125I]-Apamin is a K+ channel antagonist and can be used in the detection and quantification of K+ channel receptors. [125I]-Apamin has been used in receptor binding assays and in autoradiography.
List Price : 1415.00 USD

α-Dendrotoxin [125I] 10 µCi

NEX434 [125I]- α-Dendrotoxinsare a class of neurotoxins produced by mamba snakes that block particular subtypes of voltage-gated potassium channels in neurons. Dendrotoxins enhance the release of acetylcholine at neuromuscular junctions.
List Price : 1599.00 USD
List Price : 980.00 USD

Epidermal Growth Factor (Murine), [125I]-,10µCi

Epidermal growth factor or EGF is a growth factor that plays an important role in the regulation of cell growth, proliferation, and differentiation by binding to its receptor EGFR.
List Price : 761.00 USD

IL-6 (human, recombinant), [125I], 25µCi

NEX269 Interleukin-6 (IL-6) is a protein that in humans is encoded by the IL6 gene. IL-6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation.
List Price : 3924.00 USD

Somatostatin-14 (human, recombinant), Receptor Grade, 50µCi

NEX446 Tyr11 Somatostatin-14 is radioiodinated with no-carrier-added 125I using amodified lactoperoxidase procedure and is purified by reversed phase HPLC. This method predominantly labels tyrosine residues.
List Price : 2083.00 USD

CGRP (human), [125I]-, 50µCi

NEX354 Human CGRP binds to human CGRP receptors in the central nervous system and peripheral nervous system. [125I]-CGRP (human) will be useful in the characterization of CGRP receptors.
List Price : 1840.00 USD
List Price : 554.00 USD
List Price : 951.00 USD
List Price : 595.00 USD

PDGF [125I] (human) 5 µCi

NEX433 [125I]-PDGF BB homodimer has been shown to work in RIA and receptor studies, using CHO cell line transfected with human PDGF B receptor, and human artery smooth muscle cells.
List Price : 890.00 USD

CGP 42112A, [125I]-, 25µCi

NEX324 Extremely high selectivity makes [125I]-CGP 42112A very useful for competitive binding assays, isolation of receptors, and autoradiography.
List Price : 1669.00 USD

PDGF [125I] (human) 25 µCi

NEX433 [125I]-PDGF BB homodimer has been shown to work in RIA and receptor studies, using CHO cell line transfected with human PDGF B receptor, and human artery smooth muscle cells.
List Price : 1966.00 USD

MIP-1α (human, recombinant), [125I], 5µCi

NEX298 [125I]-MIP-1α is useful in RIA, receptor studies and crosslinking experiments in the research into immune regulation.
List Price : 700.00 USD

[125I]- Epidermal Growth Factor (h, r), 5 µCi

NEX428 Epidermal Growth Factor is radioiodinated with no carrier added 125I using a lactoperoxidase procedure and is purified by reversed phase HPLC.
List Price : 690.00 USD

Calcitonin [Tyr22] (salmon), [125I] 10 µCi

NEX423 [125I]-Calcitonin, [Tyr22] (s) is suitable for the use in radioimmunoassay as well as in the radio-receptor assay.
List Price : 846.00 USD

"Iodinated Compounds" 1-50 of 181 Products and Services

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