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Iodinated Compounds

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We provide 125I- and 131I-labeled compounds, including radioligands specific for receptor/ligand characterization for drug discovery/development and receptor distribution. Because 125I and 131I are gamma emitters, they can be counted directly without requiring scintillant. Additionally, because 125I emits Auger electrons, counting in a liquid scintillation counter is also possible.

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Application
  • Drug Discovery & Development (168)
Concentration
  • 1.0 - 10 mCi/mL (1)
  • 1.12 mCi/mL (2)
  • 1.14 mCi/mL (1)
  • 13.3 MBq/mL (1)
  • 152 µCi/mL (1)
  • 170.1 µCi/mL (2)
  • 171 µCi/mL (1)
  • 171.9 µCi/mL (2)
  • 172.5 µCi/mL (3)
  • 173.9 µCi/mL (1)
  • 182 µCi/mL (2)
  • 2.93 MBq/mL (2)
  • 236 µCi (3)
  • 3.06 MBq/mL (1)
  • 3.22 MBq/mL (1)
  • 33.7 µCi (2)
  • 345 µCi/mL (4)
  • 353 µCi/mL (5)
  • 41.4 µCi/mL (3)
  • 42.5 µCi/mL (1)
  • 45.7 µCi/mL (2)
  • 50 µCi/mL (1)
  • 6.05 MBq/mL (1)
  • 79.2 µCi/mL (2)
  • 83.8 µCi/mL (1)
  • 85.1 µCi/mL (1)
  • 86.3 µCi (1)
  • 87.2 µCi/mL (1)
  • 87.4 µCi/mL (1)
  • 87.6 µCi/mL (1)
  • 87.9 µCi/mL (1)
  • 88.5 µCi/mL (1)
  • 93.2 µCi/mL (2)
  • <1.0 µCi/mL (4)
  • <100 µCi/mL (2)
Detection Method
  • Radiometric (178)
Label Position
  • Nominally Labeled (166)
  • Specifically Labeled (15)
Product Brand Name
  • NEN Radiolabeled Ligands (178)
Radionuclide
  • 125I (180)
Receptor Type
  • 5-Hydroxytryptamine (2)
  • Adenosine (2)
  • Adrenoceptors (4)
  • Angiotensin (5)
  • Apelin (3)
  • Bombesin (4)
  • Calcitonin (3)
  • Calcium (4)
  • Chemokine (12)
  • Cholecystokinin (2)
  • Corticotropin-Releasing Factor (3)
  • Dopamine (2)
  • Endothelin (3)
  • Epidermal Growth Factor (4)
  • Ghrelin (2)
  • Glucagon (6)
  • Gonadotropin-releasing Hormone (2)
  • Growth Hormone (2)
  • Histamine (1)
  • Insulin (5)
  • Insulin-like Growth Factor (2)
  • Interleukin (4)
  • Melanin-Concentrating Hormone (2)
  • Melanocortin (4)
  • Melatonin (3)
  • Motilin (2)
  • Neuropeptide Y (6)
  • Neurotensin (2)
  • Nicotinic (7)
  • Orexin (2)
  • Oxytocin (3)
  • Peptide P518 (2)
  • Platelet-Derived Growth Factor (1)
  • Potassium (2)
  • SK channels (2)
  • Somatostatin (4)
  • Tachykinin (6)
  • Thyroid Hormone (6)
  • Transforming Growth Factor (3)
  • Urotensin (2)
  • Vasoactive Intestinal Peptide (4)
  • Vasopressin (4)
Therapeutic Area
  • Angiogenesis (12)
  • Cancer (22)
  • Cardiovascular (41)
  • CNS & Neurologic (84)
  • Diabetes (14)
  • Gastrointestinal (25)
  • Inflammation (60)
  • Metabolic Disorders (45)
  • Obesity (11)
  • Pain (22)
Volume
  • 0-50 (19)
  • 51-100 (1)
  • 201-250 (1)

"Iodinated Compounds" 1-50 of 181 Products and Services

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List Price : 1513.00 USD

Lysergic Acid Diethylamide, 2-[125I]iodo-(+), 50µCi

NEX199 Preparations have been shown to be active in binding to the serotonin receptors. LSD affects a large number of the G protein coupled receptors, including all dopamine receptor subtypes, and all adrenoreceptor subtypes, as well as many others. LSD binds to most serotonin receptor subtypes except for 5-HT3 and 5-HT4.
List Price : 2013.00 USD

Bombesin (6-14), D-Tyr6[125I], 25µCi

NEX377 [D-Tyr6[125I]-, βAla11, Phe13, Nle14]-Bombesin (6-14) is a high affinity agonist to the human Orphan Bombesin Receptor Subtype 3 (hBRS-3).
[D-Tyr6[125I]-, bAla11, Phe13, Nle14]-Bombesin (6-14) will be a useful tool to study the pharmacology of this orphan receptor as well as the natural ligand for this receptor.
List Price : 2229.00 USD

Lysergic Acid Diethylamide, 2-[125I]iodo-(+), 250µCi

NEX199 Preparations have been shown to be active in binding to the serotonin receptors. LSD affects a large number of the G protein coupled receptors, including all dopamine receptor subtypes, and all adrenoreceptor subtypes, as well as many others. LSD binds to most serotonin receptor subtypes except for 5-HT3 and 5-HT4.
List Price : 4574.00 USD

RTI-55, [125I]-, 250µCi (9.25MBq)

NEX272 [125I]-RTI-55 is an excellent radioligand for the study of the dopamine transporter sites using either tissue homogenates or autoradiographic methods--especially in regions of low receptor density.
List Price : 1715.00 USD

α-MSH, Nle4, D-Phe7, [125I], 50µCi

NEX352 α-MSH is a highly potent and metabolically stable analog of α-MSH.7 [125I]-[Nle4, D-Phe7]-α-MSH can be used to label all subtypes of melanocortin receptors with high affinity and low non-specific binding.
List Price : 2213.00 USD
List Price : 1685.00 USD

2`-Deoxycytidine-5`-triphosphate, 5-[125I]iodo-, Tetraammonium Salt, 1 mCi (37 MBq),

Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that is used whenever DNA is synthesized, such as in the polymerase chain reaction. 125I dCTP may be used to produce cDNA transcripts of viral or mRNA.
List Price : 2612.00 USD

ACTH (1-39) 23Tyr [125I], 50 µCi

[125I]ACTH is lyophilized from an acetic acid solution (0.1%) containing bovine serum albumin (0.25%), lactose (5%), L-cysteine hydrochloride (0.1%) and aprotinin (0.3TIU/ml).
List Price : 4474.00 USD

Insulin-like Growth Factor-I (human, recombinant), 5µCi

NEX241 IGF-1 is produced primarily by the liver as an endocrine hormone as well as in target tissues in a paracrine/autocrine fashion. Production is stimulated by growth hormone (GH) and can be retarded by undernutrition, growth hormone insensitivity, lack of growth hormone receptors, or failures of the downstream signalling pathway post GH receptor including SHP2 and STAT5B.
List Price : 643.00 USD
List Price : 1892.00 USD
List Price : 1033.00 USD

QRFP-43, [125I], Human Radioligand, 25µCi (925kBq)

QRFP-43 is a 43 amino acid polypeptide starting from N-terminal pyroglutamic acid and ending at C-terminal arginine-phenylalanine-amide. The intravenous administration of QRFP-43 caused the release of aldosterone, suggesting that QRFP and its receptor have a regulatory function in the rat adrenal gland.
List Price : 2477.00 USD
List Price : 707.00 USD

[125I]- Epidermal Growth Factor (h, r), 5 µCi

NEX428 Epidermal Growth Factor is radioiodinated with no carrier added 125I using a lactoperoxidase procedure and is purified by reversed phase HPLC.
List Price : 690.00 USD

α-Bungarotoxin, [125I]-Tyr54-, 500µCi (18.5MBq)

α-bungarotoxin extracted from venom of the Taiwanese banded krait (Bungarus multicinctus) binds the nicotinic acetylcholine receptor found at the neuromuscular junction and the 7 nicotinic acetylcholine receptor in the brain.
List Price : 2106.00 USD

Substance P, [125I]Tyr8], 10µCi

Substance P, [125I]Tyr8] is radioiodinated with no carrier added 125I by a lactoperoxidase procedure and is purified by reversed phase HPLC.
List Price : 1092.00 USD

Cholecystokinin Octapeptide, [125I]-, Bolton-Hunter Labeled, 50µCi

NEX203 CCK-8 mediates a number of physiological processes, including digestion and satiety. It is located in the small intestine, and detects the presence of fat in the chyme. As a neuropeptide, CCK mediates satiety by acting on the CCK receptors distributed widely throughout the central nervous system.
List Price : 3214.00 USD
List Price : 969.00 USD

S365057, [Tyr 125I], 10 µCi

NEX396 S36057 is radioiodinated with no carrier added 125I using a lactoperoxidase procedure and is purified by reversed phase HPLC.
List Price : 1249.00 USD

[125I]Tyr0-Corticotropin Releasing Factor (ovine), 10 µCi

NEX217 Corticotropin-releasing hormone (CRH), originally named corticotropin-releasing factor (CRF), and also called corticoliberin, is a polypeptide hormone and neurotransmitter involved in the stress response.
List Price : 1140.00 USD

Vasoactive Intestinal Polypeptide (human, porcine, rat), [125I], 50µCi

VIP is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method and purified by reversed phase HPLC. This method predominantly labels tyrosine residues. 
List Price : 2002.00 USD

ANGIOTENSIN I (human), [125I]Tyr4-, 50µCi (1.85MBq), Species Activity:2200Ci (81.4TBq/mmol)

NEX101 Angiotensin, a protein, causes blood vessels to constrict, and drives blood pressure up. It is part of the renin-angiotensin system, which is a major target for drugs that lower blood pressure. Angiotensin also stimulates the release of aldosterone from the adrenal cortex.
List Price : 1956.00 USD
List Price : 595.00 USD

Somatostatin-14 (human, recombinant), Receptor Grade, 50µCi

NEX446 Tyr11 Somatostatin-14 is radioiodinated with no-carrier-added 125I using amodified lactoperoxidase procedure and is purified by reversed phase HPLC. This method predominantly labels tyrosine residues.
List Price : 2083.00 USD

Vasopressin, [125I]Tyr2, Arg8-, 50µCi (1.85MBq)

NEX128 [Arg8]-Vasopressin is radioiodinated using no carrier added 125I, by a modification of the Hunter and Greenwood method and is purified by reversed phase HPLC.
List Price : 2046.00 USD
List Price : 2017.00 USD

ANGIOTENSIN I (human), [125I]Tyr4-, 10µCi (370kBq), Species Activity:2200Ci (81.4TBq/mmol)

NEX101 Angiotensin, a protein, causes blood vessels to constrict, and drives blood pressure up. It is part of the renin-angiotensin system, which is a major target for drugs that lower blood pressure. Angiotensin also stimulates the release of aldosterone from the adrenal cortex.
List Price : 816.00 USD

S365057, [Tyr 125I], 25 µCi

NEX396 S36057 is radioiodinated with no carrier added 125I using a lactoperoxidase procedure and is purified by reversed phase HPLC.
List Price : 2681.00 USD

Vasoactive Intestinal Polypeptide (human, porcine, rat), [125I], 10µCi

VIP is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method and purified by reversed phase HPLC. This method predominantly labels tyrosine residues. 
List Price : 915.00 USD

Apamin [125I]His18-NH2, 50µCi

NEX242 [125I]-Apamin is a K+ channel antagonist and can be used in the detection and quantification of K+ channel receptors. [125I]-Apamin has been used in receptor binding assays and in autoradiography.
List Price : 1415.00 USD

α-Bungarotoxin, [125I]-Tyr54-, 50µCi (1.85MBq)

α-bungarotoxin extracted from venom of the Taiwanese banded krait (Bungarus multicinctus) binds the nicotinic acetylcholine receptor found at the neuromuscular junction and the 7 nicotinic acetylcholine receptor in the brain.
List Price : 539.00 USD

IL-6 (human, recombinant), [125I], 5µCi

NEX269 Interleukin-6 (IL-6) is a protein that in humans is encoded by the IL6 gene. IL-6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation.
List Price : 1173.00 USD
List Price : 1985.00 USD

Peptide YY (Human), ([125I]-PYY), 50µCi

NEX341 [125I]-Peptide YY (human) will be useful for characterizing Peptide YY receptors.
List Price : 1903.00 USD

α-Bungarotoxin, [125I]-Tyr54-, 250µCi (9.25MBq)

α-bungarotoxin extracted from venom of the Taiwanese banded krait (Bungarus multicinctus) binds the nicotinic acetylcholine receptor found at the neuromuscular junction and the 7 nicotinic acetylcholine receptor in the brain.
List Price : 1232.00 USD

Peptide YY (Human), ([125I]-PYY), 10µCi

NEX341 [125I]-Peptide YY (human) will be useful for characterizing Peptide YY receptors.
List Price : 849.00 USD

Fractalkine (human, recombinant), 10µCi

NEX368 Fractalkine is the first member of a new class of chemokines. [125I]-Fractalkine binds with high affinity to the CX3CR1 receptor. [125I]-Fractalkine will be useful for the localization and characterization of CXCR1 receptors.
List Price : 872.00 USD

Vasopressin (Linear), V-1A Antagonist (Phenylacetyl1, 0-Me-D-Tyr2, [125I-Arg6]-),50µCi

NEX310 [125I]-Phenylacetyl-D-Tyr(Me)-Phe-Gln-Asn-Arg-Pro-Arg-Tyr-NH2 is useful in receptor studies and autoradiography for the localization and characterization of Vasopressin V1A receptors.
List Price : 2038.00 USD
List Price : 957.00 USD

Peptide YY, (Porcine), ([125I]-PYY), 10µCi

NEX240 Synthetic Peptide YY is radioiodinated with no-carrier-added 125I using a modification of the chloramine-T method.
List Price : 959.00 USD

Insulin-like Growth Factor-I (human, recombinant), 25µCi

NEX241 IGF-1 is produced primarily by the liver as an endocrine hormone as well as in target tissues in a paracrine/autocrine fashion. Production is stimulated by growth hormone (GH) and can be retarded by undernutrition, growth hormone insensitivity, lack of growth hormone receptors, or failures of the downstream signalling pathway post GH receptor including SHP2 and STAT5B.
List Price : 1577.00 USD

MIP-1α (human, recombinant), [125I], 25µCi

NEX298 [125I]-MIP-1α is useful in RIA, receptor studies and crosslinking experiments in the research into immune regulation.
List Price : 2318.00 USD

α-Bungarotoxin, [125I]-Tyr54-, High Specific Activity, 250 µCi

α-bungarotoxin extracted from venom of the Taiwanese banded krait (Bungarus multicinctus) binds the nicotinic acetylcholine receptor found at the neuromuscular junction and the 7 nicotinic acetylcholine receptor in the brain.
List Price : 1931.00 USD
List Price : 1561.00 USD
List Price : 2557.00 USD

"Iodinated Compounds" 1-50 of 181 Products and Services

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