PerkinElmer

Iodinated Compounds

OF

We provide 125I- and 131I-labeled compounds, including radioligands specific for receptor/ligand characterization for drug discovery/development and receptor distribution. Because 125I and 131I are gamma emitters, they can be counted directly without requiring scintillant. Additionally, because 125I emits Auger electrons, counting in a liquid scintillation counter is also possible.

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Application
  • Drug Discovery & Development (76)
Concentration
  • 1.0 - 10 mCi/mL (1)
  • 1.12 mCi/mL (1)
  • 1.14 mCi/mL (1)
  • 152 µCi/mL (1)
  • 170.1 µCi/mL (1)
  • 171 µCi/mL (1)
  • 172.5 µCi/mL (1)
  • 173.9 µCi/mL (1)
  • 182 µCi/mL (2)
  • 2.93 MBq/mL (1)
  • 236 µCi (1)
  • 3.06 MBq/mL (1)
  • 3.22 MBq/mL (1)
  • 33.7 µCi (1)
  • 345 µCi/mL (3)
  • 353 µCi/mL (3)
  • 41.4 µCi/mL (2)
  • 42.5 µCi/mL (1)
  • 45.7 µCi/mL (1)
  • 50 µCi/mL (1)
  • 6.05 MBq/mL (1)
  • 79.2 µCi/mL (2)
  • 83.8 µCi/mL (1)
  • 85.1 µCi/mL (1)
  • 87.2 µCi/mL (1)
  • 87.4 µCi/mL (1)
  • 87.6 µCi/mL (1)
  • 87.9 µCi/mL (1)
  • 88.5 µCi/mL (1)
  • 93.2 µCi/mL (1)
  • <1.0 µCi/mL (3)
  • <100 µCi/mL (1)
Detection Method
  • Radiometric (78)
Label Position
  • Nominally Labeled (74)
  • Specifically Labeled (5)
Product Brand Name
  • NEN Radiolabeled Ligands (77)
Radionuclide
  • 125I (79)
Receptor Type
  • Adenosine (1)
  • Adrenoceptors (2)
  • Angiotensin (4)
  • Apelin (1)
  • Bombesin (2)
  • Calcitonin (2)
  • Calcium (2)
  • Chemokine (5)
  • Cholecystokinin (1)
  • Corticotropin-Releasing Factor (1)
  • Dopamine (1)
  • Endothelin (1)
  • Epidermal Growth Factor (1)
  • Ghrelin (1)
  • Glucagon (3)
  • Gonadotropin-releasing Hormone (1)
  • Growth Hormone (1)
  • Histamine (1)
  • Insulin (3)
  • Insulin-like Growth Factor (1)
  • Interleukin (1)
  • Melanin-Concentrating Hormone (1)
  • Melanocortin (1)
  • Melatonin (1)
  • Motilin (1)
  • Neuropeptide Y (3)
  • Neurotensin (1)
  • Nicotinic (3)
  • Orexin (1)
  • Oxytocin (1)
  • Platelet-Derived Growth Factor (1)
  • Potassium (1)
  • SK channels (1)
  • Somatostatin (2)
  • Tachykinin (3)
  • Thyroid Hormone (3)
  • Transforming Growth Factor (1)
  • Urotensin (1)
  • Vasoactive Intestinal Peptide (2)
  • Vasopressin (2)
Therapeutic Area
  • Angiogenesis (8)
  • Cancer (8)
  • Cardiovascular (20)
  • CNS & Neurologic (37)
  • Diabetes (7)
  • Gastrointestinal (11)
  • Inflammation (25)
  • Metabolic Disorders (21)
  • Obesity (5)
  • Pain (9)
Volume
  • 0-50 (8)
  • 51-100 (1)
  • 201-250 (1)

"Iodinated Compounds" 1-50 of 79 Products and Services

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Price Range : 902.00 USD - 2649.00 USD

[125I]- Epidermal Growth Factor (human, rat)

NEX428 Epidermal Growth Factor is radioiodinated with no carrier added 125I using a lactoperoxidase procedure and is purified by reversed phase HPLC.
Price Range : 725.00 USD - 1599.00 USD
Price Range : 1153.00 USD - 2319.00 USD

2'-deoxycytidine-5'-triphosphate, 5-[125I]Iodo-

Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that is used whenever DNA is synthesized, such as in the polymerase chain reaction. 125I dCTP may be used to produce cDNA transcripts of viral or mRNA.
List Price : 1746.00 USD

Iodo-Melatonin, 2-[125I]

NEX236 2-[125I]-iodomelatonin has been used to identify, characterize and localize melatonin binding sites in the brain and peripheral tissues.
Price Range : 988.00 USD - 2498.00 USD

α-Dendrotoxin [125I]

NEX434 [125I]- α-Dendrotoxinsare a class of neurotoxins produced by mamba snakes that block particular subtypes of voltage-gated potassium channels in neurons. Dendrotoxins enhance the release of acetylcholine at neuromuscular junctions.
Price Range : 1054.00 USD - 1678.00 USD

CGP 42112A, [125I]

NEX324 Extremely high selectivity makes [125I]-CGP 42112A very useful for competitive binding assays, isolation of receptors, and autoradiography.
Price Range : 742.00 USD - 1752.00 USD
Price Range : 1011.00 USD - 2288.00 USD
Price Range : 1085.00 USD - 1770.00 USD

Vasopressin, [125I]Tyr2, Arg8

NEX128 [Arg8]-Vasopressin is radioiodinated using no carrier added 125I, by a modification of the Hunter and Greenwood method and is purified by reversed phase HPLC.
Price Range : 912.00 USD - 2148.00 USD
Price Range : 1513.00 USD - 2364.00 USD

RTI-55, [125I]

NEX272 [125I]-RTI-55 is an excellent radioligand for the study of the dopamine transporter sites using either tissue homogenates or autoradiographic methods--especially in regions of low receptor density.
Price Range : 904.00 USD - 1801.00 USD
List Price : 1796.00 USD

Thyroxine, ([125I]-T4), Specific Activity: 135-165 µCi/µg

NEX111 L-3,5-Diiodothyronine is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method and is purified by reversed phase HPLC.
Price Range : 651.00 USD - 1816.00 USD

Lysergic Acid Diethylamide, 2-[125I]iodo-(+), 10µCi

NEX199 Preparations have been shown to be active in binding to the serotonin receptors. LSD affects a large number of the G protein coupled receptors, including all dopamine receptor subtypes, and all adrenoreceptor subtypes, as well as many others. LSD binds to most serotonin receptor subtypes except for 5-HT3 and 5-HT4.
List Price : 880.00 USD

Bombesin (6-14), D-Tyr6[125I]

NEX377 [D-Tyr6[125I]-, βAla11, Phe13, Nle14]-Bombesin (6-14) is a high affinity agonist to the human Orphan Bombesin Receptor Subtype 3 (hBRS-3).
[D-Tyr6[125I]-, bAla11, Phe13, Nle14]-Bombesin (6-14) will be a useful tool to study the pharmacology of this orphan receptor as well as the natural ligand for this receptor.
Price Range : 1269.00 USD - 2385.00 USD
Price Range : 776.00 USD - 1257.00 USD

α-Bungarotoxin, [125I]-Tyr54

α-bungarotoxin extracted from venom of the Taiwanese banded krait (Bungarus multicinctus) binds the nicotinic acetylcholine receptor found at the neuromuscular junction and the 7 nicotinic acetylcholine receptor in the brain.
Price Range : 566.00 USD - 2527.00 USD

Insulin (porcine), Receptor Grade, [125I]TyrA14]

[125I]TyrA14 Insulin has been proven to be active in a receptor binding assay using cultured human fibroblasts as described.8 It may also be used in radioimmunoassay.
Price Range : 1153.00 USD - 2250.00 USD

2`-Deoxycytidine-5`-triphosphate, 5-[125I] iodo-, Tetraammonium Salt

Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that is used whenever DNA is synthesized, such as in the polymerase chain reaction. 125I dCTP may be used to produce cDNA transcripts of viral or mRNA.
Price Range : 1097.00 USD - 2742.00 USD

SDF-1α (human, recombinant), [125I]

NEX346 SDF-1 a acts at the CXCR4 (fusin or LESTR) receptor. 125I-SDF-1 a competes with SDF-1 a in CXCR4 receptor binding assays.
Price Range : 744.00 USD - 1999.00 USD
Price Range : 943.00 USD - 1808.00 USD

Somatostatin-14 (human, recombinant), [125I], Receptor Grade

NEX446 Tyr11 Somatostatin-14 is radioiodinated with no-carrier-added 125I using amodified lactoperoxidase procedure and is purified by reversed phase HPLC. This method predominantly labels tyrosine residues.
Price Range : 945.00 USD - 2291.00 USD

Vasopressin (Linear), V-1A Antagonist (Phenylacetyl1, 0-Me-D-Tyr2, [125I-Arg6]-)

NEX310 [125I]-Phenylacetyl-D-Tyr(Me)-Phe-Gln-Asn-Arg-Pro-Arg-Tyr-NH2 is useful in receptor studies and autoradiography for the localization and characterization of Vasopressin V1A receptors.
Price Range : 964.00 USD - 2140.00 USD
Price Range : 582.00 USD - 1589.00 USD

S365057, [Tyr 125I]

NEX396 S36057 is radioiodinated with no carrier added 125I using a lactoperoxidase procedure and is purified by reversed phase HPLC.
Price Range : 1312.00 USD - 2815.00 USD

Fractalkine (human, recombinant), 125I

NEX368 Fractalkine is the first member of a new class of chemokines. [125I]-Fractalkine binds with high affinity to the CX3CR1 receptor. [125I]-Fractalkine will be useful for the localization and characterization of CXCR1 receptors.
Price Range : 959.00 USD - 2117.00 USD
Price Range : 998.00 USD - 3477.00 USD

Neurokinin A, ([125I]-Substance K

NEX252 [125I]-NKA is a radioiodinated tachykinin which binds selectively to NK-2 receptors. Typical lots have been tested in a specific NK-2 radioreceptor assay. We do not recommend its use in a radioimmunoassay. The presence of a non-oxidized methionine typically leads to low antibody binding.
Price Range : 818.00 USD - 1966.00 USD

α-Bungarotoxin, [125I]-Tyr54-, High Specific Activity

α-bungarotoxin extracted from venom of the Taiwanese banded krait (Bungarus multicinctus) binds the nicotinic acetylcholine receptor found at the neuromuscular junction and the 7 nicotinic acetylcholine receptor in the brain.
Price Range : 644.00 USD - 2028.00 USD

Peptide YY, (Porcine), ([125I]-PYY)

NEX240 Synthetic Peptide YY is radioiodinated with no-carrier-added 125I using a modification of the chloramine-T method.
Price Range : 1007.00 USD - 2326.00 USD

GLP-1 (7-36), [125I]

NEX308 Glucagon-like peptide-1 (GLP-1) is derived from the transcription product of the proglucagon gene. The major source of GLP-1 in the body is the intestinal L cell that secretes GLP-1 as a gut hormone. The biologically active forms of GLP-1 are: GLP-1-(7-37) and GLP-1-(7-36)NH2.
Price Range : 1219.00 USD - 2224.00 USD
Price Range : 1005.00 USD - 2102.00 USD

Insulin (human, recombinant), [125I]

[125I]-Insulin (h) is suitable for the use in radioimmunoassay as well as receptor binding assay. [125I]-Insulin (h) is radioiodinated with no carrier added 125I using the LPO iodination procedure and is purified by reversed phase HPLC.
Price Range : 1085.00 USD - 2112.00 USD

CGRP (human), [125I]

NEX354 Human CGRP binds to human CGRP receptors in the central nervous system and peripheral nervous system. [125I]-CGRP (human) will be useful in the characterization of CGRP receptors.
Price Range : 797.00 USD - 1932.00 USD
Price Range : 845.00 USD - 2117.00 USD

Apamin [125I]His18-NH2

NEX242 [125I]-Apamin is a K+ channel antagonist and can be used in the detection and quantification of K+ channel receptors. [125I]-Apamin has been used in receptor binding assays and in autoradiography.
Price Range : 910.00 USD - 1514.00 USD

Ghrelin (human), [His[125I]]

NEX388 Ghrelin is an acylated endogenous peptide which stimulates the release of growth hormone from the pituitary through an orphan G-protein-coupled receptor (GHS-R)7. Ghrelin is an appetite inducing hormone produced in the stomach and the upper portion of the small intestine. [ [125I]His ]Ghrelin (human), binds to GHS-R with high affinity.
Price Range : 1350.00 USD - 2630.00 USD

Bombesin, [125I]Tyr4

NEX258 [125I]-Bombesin will be useful as a tracer in RIAs for bombesin like peptides, and as a high specific activity ligand in receptor studies.
Price Range : 1041.00 USD - 2226.00 USD

Insulin-like Growth Factor-I (human, recombinant), 125I

NEX241 IGF-1 is produced primarily by the liver as an endocrine hormone as well as in target tissues in a paracrine/autocrine fashion. Production is stimulated by growth hormone (GH) and can be retarded by undernutrition, growth hormone insensitivity, lack of growth hormone receptors, or failures of the downstream signalling pathway post GH receptor including SHP2 and STAT5B.
Price Range : 675.00 USD - 1656.00 USD

Angiotensin I (human), [125I]Tyr4

NEX101 Angiotensin, a protein, causes blood vessels to constrict, and drives blood pressure up. It is part of the renin-angiotensin system, which is a major target for drugs that lower blood pressure. Angiotensin also stimulates the release of aldosterone from the adrenal cortex.
Price Range : 857.00 USD - 2054.00 USD
Price Range : 743.00 USD - 1951.00 USD

IP-10 (human, recombinant), [125I]-, Bolton-Hunter Labeled

NEX348 IP-10 acts at the CXCR3 receptor and attracts T cells, particularly activated T cells.
Price Range : 744.00 USD - 1804.00 USD

ANGIOTENSIN II (human), [125I]-Tyr4 -50 μCi

NEX105 Packaged lyophilized from phosphate-buffered saline containing glycine, BSA and Trasylol®
List Price : 2031.00 USD
Price Range : 1317.00 USD - 2941.00 USD

α-MSH, Nle4, D-Phe7, [125I]

NEX352 α-MSH is a highly potent and metabolically stable analog of α-MSH.7 [125I]-[Nle4, D-Phe7]-α-MSH can be used to label all subtypes of melanocortin receptors with high affinity and low non-specific binding.
Price Range : 1036.00 USD - 2324.00 USD

"Iodinated Compounds" 1-50 of 79 Products and Services