PerkinElmer

Iodinated Compounds

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We provide 125I- and 131I-labeled compounds, including radioligands specific for receptor/ligand characterization for drug discovery/development and receptor distribution. Because 125I and 131I are gamma emitters, they can be counted directly without requiring scintillant. Additionally, because 125I emits Auger electrons, counting in a liquid scintillation counter is also possible.

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Application
  • Drug Discovery & Development (168)
Concentration
  • 1.0 - 10 mCi/mL (1)
  • 1.12 mCi/mL (2)
  • 1.14 mCi/mL (1)
  • 13.3 MBq/mL (1)
  • 152 µCi/mL (1)
  • 170.1 µCi/mL (2)
  • 171 µCi/mL (1)
  • 171.9 µCi/mL (2)
  • 172.5 µCi/mL (3)
  • 173.9 µCi/mL (1)
  • 182 µCi/mL (2)
  • 2.93 MBq/mL (2)
  • 236 µCi (3)
  • 3.06 MBq/mL (1)
  • 3.22 MBq/mL (1)
  • 33.7 µCi (2)
  • 345 µCi/mL (4)
  • 353 µCi/mL (5)
  • 41.4 µCi/mL (3)
  • 42.5 µCi/mL (1)
  • 45.7 µCi/mL (2)
  • 50 µCi/mL (1)
  • 6.05 MBq/mL (1)
  • 79.2 µCi/mL (2)
  • 83.8 µCi/mL (1)
  • 85.1 µCi/mL (1)
  • 86.3 µCi (1)
  • 87.2 µCi/mL (1)
  • 87.4 µCi/mL (1)
  • 87.6 µCi/mL (1)
  • 87.9 µCi/mL (1)
  • 88.5 µCi/mL (1)
  • 93.2 µCi/mL (2)
  • <1.0 µCi/mL (4)
  • <100 µCi/mL (2)
Detection Method
  • Radiometric (178)
Label Position
  • Nominally Labeled (166)
  • Specifically Labeled (15)
Product Brand Name
  • NEN Radiolabeled Ligands (178)
Radionuclide
  • 125I (180)
Receptor Type
  • 5-Hydroxytryptamine (2)
  • Adenosine (2)
  • Adrenoceptors (4)
  • Angiotensin (5)
  • Apelin (3)
  • Bombesin (4)
  • Calcitonin (3)
  • Calcium (4)
  • Chemokine (12)
  • Cholecystokinin (2)
  • Corticotropin-Releasing Factor (3)
  • Dopamine (2)
  • Endothelin (3)
  • Epidermal Growth Factor (4)
  • Ghrelin (2)
  • Glucagon (6)
  • Gonadotropin-releasing Hormone (2)
  • Growth Hormone (2)
  • Histamine (1)
  • Insulin (5)
  • Insulin-like Growth Factor (2)
  • Interleukin (4)
  • Melanin-Concentrating Hormone (2)
  • Melanocortin (4)
  • Melatonin (3)
  • Motilin (2)
  • Neuropeptide Y (6)
  • Neurotensin (2)
  • Nicotinic (7)
  • Orexin (2)
  • Oxytocin (3)
  • Peptide P518 (2)
  • Platelet-Derived Growth Factor (1)
  • Potassium (2)
  • SK channels (2)
  • Somatostatin (4)
  • Tachykinin (6)
  • Thyroid Hormone (6)
  • Transforming Growth Factor (3)
  • Urotensin (2)
  • Vasoactive Intestinal Peptide (4)
  • Vasopressin (4)
Therapeutic Area
  • Angiogenesis (12)
  • Cancer (22)
  • Cardiovascular (41)
  • CNS & Neurologic (84)
  • Diabetes (14)
  • Gastrointestinal (25)
  • Inflammation (60)
  • Metabolic Disorders (45)
  • Obesity (11)
  • Pain (22)
Volume
  • 0-50 (19)
  • 51-100 (1)
  • 201-250 (1)

"Iodinated Compounds" 1-50 of 181 Products and Services

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LH-RH, [125I]-[D-Trp6]-, 10µCi

NEX365 [125I]-[D-Trp6]-LH-RH will be useful for receptor binding studies in cell lines and tissue cultures.
List Price : 997.00 USD

Fractalkine (human, recombinant), 25µCi

NEX368 Fractalkine is the first member of a new class of chemokines. [125I]-Fractalkine binds with high affinity to the CX3CR1 receptor. [125I]-Fractalkine will be useful for the localization and characterization of CXCR1 receptors.
List Price : 2017.00 USD

Somatostatin, [125I]Tyr11, 10µCi

NEX389 Somatostatin is a cyclic neuropeptide found in the brain, pancreas and hypothalamus and inhibits the release of growth hormone. [125I ] Tyr11 somatostatin binds to the receptors on RINm5F insolinoma cells with high affinity and inhibits the secretion of insulin from pancreatic b cells.
List Price : 861.00 USD

Bombesin, [125I]Tyr4-, 10µCi (370kBq)

NEX258 [125I]-Bombesin will be useful as a tracer in RIAs for bombesin like peptides, and as a high specific activity ligand in receptor studies.
List Price : 992.00 USD
List Price : 882.00 USD

Substance P, [125I]Tyr8], 50µCi

Substance P, [125I]Tyr8] is radioiodinated with no carrier added 125I by a lactoperoxidase procedure and is purified by reversed phase HPLC.
List Price : 2356.00 USD

Lysergic Acid Diethylamide, 2-[125I]iodo-(+), 50µCi

NEX199 Preparations have been shown to be active in binding to the serotonin receptors. LSD affects a large number of the G protein coupled receptors, including all dopamine receptor subtypes, and all adrenoreceptor subtypes, as well as many others. LSD binds to most serotonin receptor subtypes except for 5-HT3 and 5-HT4.
List Price : 2013.00 USD
List Price : 759.00 USD

Peptide YY, (Porcine), ([125I]-PYY), 50µCi

NEX240 Synthetic Peptide YY is radioiodinated with no-carrier-added 125I using a modification of the chloramine-T method.
List Price : 2215.00 USD
List Price : 1561.00 USD

MCP-1,[125I]- labeled, Bolton-Hunter Labeled, 5µCi

NEX313 Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). It is found at the site of tooth eruption and bone degradation. In the bone, CCL2 is expressed by mature osteoclasts and osteoblasts and is under the control of nuclear factor κB (NFκB).
List Price : 698.00 USD
List Price : 1633.00 USD

Vasopressin, [125I]Tyr2, Arg8-, 50µCi (1.85MBq)

NEX128 [Arg8]-Vasopressin is radioiodinated using no carrier added 125I, by a modification of the Hunter and Greenwood method and is purified by reversed phase HPLC.
List Price : 2046.00 USD

Somatostatin, [125I]Tyr11, 50µCi

NEX389 Somatostatin is a cyclic neuropeptide found in the brain, pancreas and hypothalamus and inhibits the release of growth hormone. [125I ] Tyr11 somatostatin binds to the receptors on RINm5F insolinoma cells with high affinity and inhibits the secretion of insulin from pancreatic b cells.
List Price : 2007.00 USD

[125I]Tyr0-Corticotropin Releasing Factor (ovine), 50 µCi

NEX217 Corticotropin-releasing hormone (CRH), originally named corticotropin-releasing factor (CRF), and also called corticoliberin, is a polypeptide hormone and neurotransmitter involved in the stress response.
List Price : 2448.00 USD

Peptide YY (Human), ([125I]-PYY), 10µCi

NEX341 [125I]-Peptide YY (human) will be useful for characterizing Peptide YY receptors.
List Price : 849.00 USD

Cholecystokinin Octapeptide, [125I]-, Bolton-Hunter Labeled, 10µCi

NEX203 CCK-8 mediates a number of physiological processes, including digestion and satiety. It is located in the small intestine, and detects the presence of fat in the chyme. As a neuropeptide, CCK mediates satiety by acting on the CCK receptors distributed widely throughout the central nervous system.
List Price : 979.00 USD

Iodo-Melatonin, 2-[125I], 50µCi

NEX236 2-[125I]-iodomelatonin has been used to identify, characterize and localize melatonin binding sites in the brain and peripheral tissues.
List Price : 941.00 USD

Bombesin (6-14), D-Tyr6[125I], 25µCi

NEX377 [D-Tyr6[125I]-, βAla11, Phe13, Nle14]-Bombesin (6-14) is a high affinity agonist to the human Orphan Bombesin Receptor Subtype 3 (hBRS-3).
[D-Tyr6[125I]-, bAla11, Phe13, Nle14]-Bombesin (6-14) will be a useful tool to study the pharmacology of this orphan receptor as well as the natural ligand for this receptor.
List Price : 2229.00 USD

Calcitonin [Tyr22] (salmon), [125I] 10 µCi

NEX423 [125I]-Calcitonin, [Tyr22] (s) is suitable for the use in radioimmunoassay as well as in the radio-receptor assay.
List Price : 846.00 USD

Vasoactive Intestinal Polypeptide (human, porcine, rat), [125I], 50µCi

VIP is radioiodinated with no carrier added 125I using a modification of the Hunter and Greenwood method and purified by reversed phase HPLC. This method predominantly labels tyrosine residues. 
List Price : 2002.00 USD

ACTH (1-39) 23Tyr [125I], 50 µCi

[125I]ACTH is lyophilized from an acetic acid solution (0.1%) containing bovine serum albumin (0.25%), lactose (5%), L-cysteine hydrochloride (0.1%) and aprotinin (0.3TIU/ml).
List Price : 4474.00 USD

Epidermal Growth Factor (Murine), [125I]-,10µCi

Epidermal growth factor or EGF is a growth factor that plays an important role in the regulation of cell growth, proliferation, and differentiation by binding to its receptor EGFR.
List Price : 761.00 USD

MCP-1,[125I]- labeled, Bolton-Hunter Labeled, 25µCi

NEX313 Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). It is found at the site of tooth eruption and bone degradation. In the bone, CCL2 is expressed by mature osteoclasts and osteoblasts and is under the control of nuclear factor κB (NFκB).
List Price : 1646.00 USD

S365057, [Tyr 125I], 25 µCi

NEX396 S36057 is radioiodinated with no carrier added 125I using a lactoperoxidase procedure and is purified by reversed phase HPLC.
List Price : 2681.00 USD

[125I]- Epidermal Growth Factor (h, r), 5 µCi

NEX428 Epidermal Growth Factor is radioiodinated with no carrier added 125I using a lactoperoxidase procedure and is purified by reversed phase HPLC.
List Price : 690.00 USD

Epidermal Growth Factor (Murine), [125I]-,50µCi

Epidermal growth factor or EGF is a growth factor that plays an important role in the regulation of cell growth, proliferation, and differentiation by binding to its receptor EGFR.
List Price : 1943.00 USD

2`-Deoxycytidine-5`-triphosphate, 5-[125I]iodo-, Tetraammonium Salt, 100µCi (3.7MBq)

Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that is used whenever DNA is synthesized, such as in the polymerase chain reaction. 125I dCTP may be used to produce cDNA transcripts of viral or mRNA.
List Price : 1044.00 USD

Somatostatin-14 (human, recombinant), Receptor Grade, 10 µCi

NEX446 Tyr11 Somatostatin-14 is radioiodinated with no-carrier-added 125I using amodified lactoperoxidase procedure and is purified by reversed phase HPLC. This method predominantly labels tyrosine residues.
List Price : 859.00 USD

IL-6 (human, recombinant), [125I], 5µCi

NEX269 Interleukin-6 (IL-6) is a protein that in humans is encoded by the IL6 gene. IL-6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation.
List Price : 1173.00 USD
List Price : 1892.00 USD

GLP-1 (7-36), [125I]-, 50µCi (1.85MBq)

NEX308 Glucagon-like peptide-1 (GLP-1) is derived from the transcription product of the proglucagon gene. The major source of GLP-1 in the body is the intestinal L cell that secretes GLP-1 as a gut hormone. The biologically active forms of GLP-1 are: GLP-1-(7-37) and GLP-1-(7-36)NH2.
List Price : 2118.00 USD

SDF-1α (human, recombinant), [125I]-, 25µCi

NEX346 SDF-1 a acts at the CXCR4 (fusin or LESTR) receptor. 125I-SDF-1 a competes with SDF-1 a in CXCR4 receptor binding assays.
List Price : 1903.00 USD

Peptide YY (Human), ([125I]-PYY), 50µCi

NEX341 [125I]-Peptide YY (human) will be useful for characterizing Peptide YY receptors.
List Price : 1903.00 USD

GLP-1 (7-36), [125I]-, 10µCi (370kBq)

NEX308 Glucagon-like peptide-1 (GLP-1) is derived from the transcription product of the proglucagon gene. The major source of GLP-1 in the body is the intestinal L cell that secretes GLP-1 as a gut hormone. The biologically active forms of GLP-1 are: GLP-1-(7-37) and GLP-1-(7-36)NH2.
List Price : 1161.00 USD

Bombesin (6-14), D-Tyr6[125I], 10µCi

NEX377 [D-Tyr6[125I]-, βAla11, Phe13, Nle14]-Bombesin (6-14) is a high affinity agonist to the human Orphan Bombesin Receptor Subtype 3 (hBRS-3).
[D-Tyr6[125I]-, bAla11, Phe13, Nle14]-Bombesin (6-14) will be a useful tool to study the pharmacology of this orphan receptor as well as the natural ligand for this receptor.
List Price : 1208.00 USD

IP-10 (human, recombinant), [125I]-, Bolton-Hunter Labeled, 25µCi

NEX348 IP-10 acts at the CXCR3 receptor and attracts T cells, particularly activated T cells.
List Price : 1718.00 USD

Glucagon, Receptor Grade, [125I]-, 50µCi

NEX207 Glucagon is radioiodinated with no carrier added 125I by a lactoperoxidase procedure and is purified by reversed phase HPLC. [125I]-Glucagon consists of an approximately 1:1 ratio of Tyr10 and Tyr13 labeled glucagon. Met27 is in its native thioether form.
List Price : 2067.00 USD
List Price : 957.00 USD
List Price : 554.00 USD

"Iodinated Compounds" 1-50 of 181 Products and Services

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