PerkinElmer

Image Analysis Software

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Extract meaningful data that leads to new insights and enables faster and more confident decision making. Our powerful image analysis software makes it easy for you to generate and analyze image data from cellular, in vivo and tissue samples so that you confidently move your digital pathology research forward.

  • High Content Screening: Turn your cellular data into knowledge with our high content analysis software - analyze complex cellular models, reliably discriminate phenotypes, and efficiently manage the large quantities of data your lab generates from high content screening
  • In vivo Imaging: Analyze even complex in vivo data with ease using our portfolio of in vivo imaging software analysis tools - whether it's 2D or 3D optical imaging analysis with co-registration or advanced microCT analysis and visualization
  • Tissue Samples: Quantify and phenotype cells labeled with multiple biomarkers in situ in FFPE tissue sections

For research use only. Not for use in diagnostic procedures.

Business Insights (3)
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  • Application Note

    Measuring FRET using the Opera Phenix High-Content Screening System

    Fundamental processes in living cells, such as apoptosis and signal transduction are controlled by proteins, often acting in concert with other protein partners through protein-protein interactions (PPIs). Inappropriate protein-protein recognition can fundamentally contribute to many diseases, including cancer. Therefore, inhibiting protein-protein interactions represents an emerging area in drug design.

  • Application Note

    Imaging Bile Canaliculi in 3D Liver Microtissues using the Opera Phenix HCS System

    Analyzing transport of biliary metabolites is essential to predict pharmacokinetics and hepatotoxicity during drug development. A functional impairment of hepatobilary transporters, such as bile salt export pump (BSEP) and multidrug resistance-associated protein 2 (MRP-2), is strongly associated with an increased risk of cholestatic liver injury. Here, we describe a 3D high-content screening assay to study hepatobiliary transporter function in InSphero human liver microtissues. Confocal imaging and automated image analysis were used to quantify BSEP and MRP-2-mediated efflux of fluorescent substrates into bile canaliculi.

  • Application Note

    MicroCT Investigation of Bone Erosion and Deformation in an Osteoarthritic Rat Model

    Osteoarthritis (OA) is the most common form of arthritis and affects a considerable portion of the elderly population. In the U.S., it is estimated that more than 630 million people worldwide have this chronic condition, generally in the knees. OA occurs when the cartilage that cushions the ends of bones within the joints gradually deteriorates, causing synovitis and joint deformation.

    The goal of OA research is to identify new therapeutic strategies that could prevent, reduce, halt progression, or repair the existing damage to the joint. Non-invasive in vivo imaging such as microCT is the standard modality for bone research due to its ability to obtain high-resolution images at an x-ray dose low enough as not to harm the animal. This makes microCT ideal for monitoring disease progression and response to treatments in the same animal over time. However, microCT data visualization and analysis can be cumbersome and time consuming. In this application note, we compared standard microCT software and advanced bone software to investigate bone erosion in an OA rat model.

Products & Services (12)
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  • Fluorescence tomograhy of mouse analyzed with TrueQuant

    TrueQuant Imaging Software

    Fluorescence Tomography Acquisition and Analysis for FMT Platform

    TrueQuant software makes 3D fluorescence tomography easy with streamlined tools for data management, automatic reconstruction, and high throughput data analysis.

  • HALO image analysis software for quantification of whole slide and multispectral imagery

    HALO Image Analysis Software

    PerkinElmer has partnered with Indica Labs to offer HALO, a full suite of image analysis solutions to extend quantification of biomarkers to whole tissue samples. HALO is an expandable, modular platform that enables fast and easy quantification of biomarkers in brightfield and fluorescent whole slide imagery and multispectral fields-of-view, ideal for use in immuno-oncology, neuroscience and many other research areas. It is compatible with images acquired on the Vectra®, Vectra Polaris and Mantra multiplex biomarker imaging systems.
  • Separation bone and vascular contrast agent using Living Image

    Living Image Software – IVIS Spectrum Series

    Advanced Acquisition and Analysis Tools for IVIS® Spectrum Imaging Systems

    Living Image® advanced in vivo imaging software designed for the IVIS Spectrum platform simplifies even the most complex image acquisition and analysis of bioluminescent and fluorescent probes. The Living Image software version for the IVIS Spectrum platform includes all 2D features of the IVIS Lumina software but adds 3D data analysis including optical tomography and co-registration with other modalities, Living Image in vivo imaging software sets the industry standard for ease of use and flexibility.
  • HALO Link collaborative pathology information system

    HALO Link Collaborative Pathology Information System

    PerkinElmer has partnered with Indica Labs to bring to you HALO Link Collaborative Pathology Information System. HALO Link combines cloud-based image management with HALO image analysis and is compatible with images acquired on the Vectra®, Vectra Polaris and Mantra Multiplex Biomarker Imaging Systems.
  • Harmony Software 1

    Harmony High-Content Imaging and Analysis Software

    Easily quantify complex cellular phenotypes with Harmony high-content analysis software. Harmony software is designed for Operetta CLS and Opera Phenix high-content screening systems.

    Coming soon!
    Our forthcoming release includes an updated version of PreciScan, which significantly reduces imaging times and data volumes for 3D cell models grown in hydrogels.

  • Multimodality imaging PET, microCT, FLIT, using VivoQuant

    Multimodality Imaging Software Solutions

    When Modalities Combine You See Disease In All Its Dimensions

    Maximize your data and gain unique insights into your research by combining images from multiple modalities, including optical, microCT, and PET. Co-registration allows researchers to overlay images from multiple imaging modalities, providing more comprehensive insight into the molecular and anatomical features of a model subject.
  • inForm monitor

    inForm Tissue Finder

    inForm® Tissue Finder adds exceptional functionality to inForm Cell Analysis to automate the detection and segmentation of specific tissues through powerful patented pattern recognition algorithms. Automation provides consistent reproducible results and enables comparative studies of multiple markers and specimens, supporting researchers to make faster discoveries of the indicators of disease.
  • MicroCT Imaging Bone segmentation using AccuCT Software

    AccuCT microCT Analysis Software

    Advanced Bone Analysis for Quantum microCT Imaging Systems

    With AccuCT™ advanced microCT imaging software, researchers can perform ASBMR (American Society for Bone and Mineral Research) bone morphometry and BMD (Bone Mineral Density) analysis on data acquired on their Quantum (FX and GX) microCT system with just a few mouse clicks.
  • inForm monitor

    inForm Cell Analysis

    inForm® Cell Analysis enables quantitative per cell analysis of immunohistochemistry (IHC), immunofluorescence (IF), and RNA in-situ hybridization, enabling the separation of weak and spectrally overlapping markers, in single and multiplex assays.
  • Mice imaging using IVIS Lumina and Living Image Software

    Living Image Software – IVIS Lumina Series

    Advanced Acquisition and Analysis Tools for IVIS® Lumina Imaging Systems

    Living Image® advanced in vivo imaging software designed for the IVIS Lumina platform simplifies even the most complex image acquisition and analysis of 2D bioluminescent and fluorescent probes. With streamlined interfaces and workflows for longitudinal analysis of 2D data including co-registration with X-ray in applicable IVIS Lumina systems, Living Image in vivo imaging software sets the industry standard for ease of use and flexibility.
  • Phenologic 1

    PhenoLOGIC Machine Learning

    PhenoLOGIC enables biologists using Harmony to train the software to develop the image analysis algorithms. While other systems may require an image analysis expert to create an algorithm, PhenoLOGIC uses proprietary machine-learning technology to make it easy for you to do it on your own. Using a learn-by-example approach, images can be segmented with just a few clicks of the mouse and then tailored algorithms developed quickly and easily.
  • PreciScan intelligent acquisition software lets you first pre-scan at low magnification

    PreciScan Intelligent Acquisition

    Harness the power of intelligent image acquisition with PreciScan for more efficient high-content imaging and analysis. This optional plug-in for Harmony high-content analysis software enables you to more accurately target your object of interest for significantly reduced acquisition and analysis times, particularly valuable for 3D microtissue and rare event studies.