PerkinElmer

Epigenetics Research

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The study of gene expression is opening new doors for drug discovery. Our epigenetics solutions include cellular detection kits and epigenetic assays for readers, writers, and erasers – allowing you to characterize multiple targets, shorten assay development time, and accelerate drug discovery.

Benefits of epigenetics kits and assays include:

  • Flexibility: Work with peptide or full-length protein substrates, or endogenous histones in biochemical or cell-based format
  • Sensitivity: Robust and reproducible detection, even at low enzyme concentrations
  • Specificity: Reagents highly specific for the mark of interest
  • Simplicity: One-well, no-wash assay platforms amenable to automation and HTS
  • Validated: Detailed, ready-to-use protocols for over 30 epigenetic enzyme assays

Drugs that can alter cellular traits have particular importance for conditions related to epigenetic modification, including cancer, mental illness, and heart disease. As knowledge of gene expression in disease states advances, so too does the possibility for epigenetic drugs.

Whether you need an epigenetics kit or validated assay, our suite of epigenetics research reagents offers a faster, more efficient path in the race to identify promising epigenetic drug candidates.

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Product Type
  • Instruments (3)
  • Reagents (103)
  • Services (1)
Assay Target
  • Histone H2A (1)
  • Histone H3 (9)
  • Histone H4 (1)
Target Species
  • Human (1)
Application
  • Epigenetics (49)
  • Mobility Shift (3)
  • Molecular Biology (41)
  • Protein Analysis & Detection (6)
  • Protein-protein interactions (7)
Therapeutic Area
  • Epigenetics (11)
Product Brand Name
  • Alpha (1)
  • AlphaLISA (35)
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Detection Method
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  • Radiometric (41)
  • Time-Resolved Fluorescence (TRF) (23)
  • TR-FRET (15)
Molecular Modification
  • Acetylation (12)
  • GlcNAc (1)
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Sample Type
  • Enzyme (3)
Antibody Conjugates
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Label Position
  • alpha (30)
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Buffer
  • Tricine (18)
  • Tricine with stabilizer and dye (20)
Assay points(200-50,000)
  • 100 (9)
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Assay Target Class
  • Histone (11)
Automation Compatible
  • Yes (59)
Concentration
  • 10 mCi/mL (22)
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Experimental Type
  • In vitro (54)
Format
  • Microplates (55)

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