PerkinElmer

CNS

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You'll gain the greatest possible insights into central nervous system targets and disorders in vitro, in situ, and in vivo – using our broad range of products for the neurologic researcher.

Assess mechanisms of central nervous system disease in biochemical, cellular, tissue, and animal models with our biomarker detection kits, cellular and in vivo imaging systems, and tissue pathology solutions, our target-specific radiochemicals, radioligands, and receptor-transfected cell lines and cell membranes, and informatics solutions.

  • Accurately detect and quantitate biomarkers of central nervous system disease in cells, brain tissue homogenates, cerebrospinal fluid, and other sample types, using our fast, simple, pre-validated kits
  • Effectively study targeted binding using our radiolabeled ligands and steroids
  • Quantitate biomarkers in tissue samples through our industry-leading immunohistochemistry solutions
  • Probe the biological processes in animal models from molecular, functional, and anatomical perspectives with our in vivo imaging systems
  • Gain deeper insights from phenotypic analysis with our high content screening solutions
  • Make data-driven decisions for neurologic research using advanced statistics, machine learning and data analysis methods obtaining reproducible and objective results with our informatics solutions

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Product Type
  • Accessories (34)
  • Consumables (2)
  • Reagents (162)
  • Software and Informatics (7)
Application
  • cAMP (11)
  • Drug Discovery & Development (46)
  • Immunohistochemistry (IHC) (23)
  • In situ hybridization (ISH) (23)
  • Molecular Biology (14)
  • Protein Analysis & Detection (21)
Assay points(200-50,000)
  • 10000 (5)
  • 500 (15)
  • 5000 (9)
Assay Target
  • Aβ1-40 (4)
  • Aβ1-42 (2)
  • Aβ1-x (1)
  • Aβ40 (3)
  • Aβ42 (1)
  • BDNF (2)
  • EPO (1)
  • Frataxin (2)
  • GAD67 (2)
  • Tau (1)
  • TDP-43 (2)
Assay Target Class
  • Cytokine (1)
  • GPCR (80)
  • Ion channel (3)
  • Peptide (10)
  • Protein (10)
Assay Validated
  • Binding (72)
  • Calcium Fluorescence (16)
  • Calcium Luminescence (32)
  • cAMP (20)
  • Downstream Phosphorylation (5)
  • GTPγS (19)
  • Inositol Phosphate (3)
Automation Compatible
  • Yes (21)
Buffer
  • Tricine (2)
  • Tricine with stabilizer and dye (12)
Concentration
  • 10 mCi/mL (10)
  • 12.5 mCi/mL (1)
Detection Method
  • Alpha (11)
  • Chromogenic (6)
  • Fluorescence (25)
  • Radiometric (15)
  • Time-Resolved Fluorescence (TRF) (10)
  • TR-FRET (10)
Experimental Type
  • In vitro (21)
Fluorophore
  • Coumarin (1)
  • Cy3 (8)
  • Cy5 (4)
  • Fluorescein (6)
  • TMR (5)
Format
  • Microplates (21)
  • Slides (23)
Host Cell
  • 1321N1 (4)
  • CHO-K1 (65)
  • HEK293 (13)
  • L Cells (1)
  • UC11 (1)
Label Position
  • alpha (11)
  • gamma (3)
  • Nominally Labeled (1)
Nucleotide
  • ATP (3)
  • CTP (1)
  • dATP (2)
  • dCTP (2)
  • dTTP (1)
  • GTP (1)
  • UTP (4)
Product Brand Name
  • AequoScreen (14)
  • AequoZen (12)
  • AlphaLISA (11)
  • Ancillary Products (2)
  • cAMPZen (7)
  • EasyTide (7)
  • LANCE Ultra (10)
  • Membrane Target Systems (35)
  • NEN (2)
  • NEN Radiochemicals (6)
  • Opera Phenix (7)
  • Operetta (29)
  • TSA (12)
  • TSA Plus (12)
  • ValiScreen (15)
Radionuclide
  • 33P (12)
  • 35S (2)
  • 3H (1)
Radioisotope
  • H-3 (1)
  • P-33 (12)
  • S-35 (2)
Receptor Type
  • 5-Hydroxytryptamine (Serotonin) (38)
  • Adrenergic (10)
  • Cannabinoid (9)
  • Dopamine (8)
  • GABA (4)
  • Galanin (10)
  • Neurotensin (4)
  • Nicotinic (4)
  • Opioid (11)
  • Tachykinin (1)
Target Species
  • Human (19)
  • Mouse (2)
Therapeutic Area
  • Angiogenesis (9)
  • Cardiovascular (37)
  • Central Nervous System (92)
  • CNS & Neurologic (1)
  • Diabetes (10)
  • Gastrointestinal (31)
  • Inflammation (51)
  • Metabolic (30)
  • Obesity (1)
  • Pain (21)
Volume
  • 0-50 (1)
Volume Capacity
  • 150 µL (2)

"CNS" 1-50 of 205 Products and Services

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ATP, [γ-33P]- 3000Ci/mmol, 10mCi/ml

Adenosine triphosphate, labeled on the gamma phosphate group with 33P.
Price Range : 693.00 USD - 1857.00 USD
Receptor-expressing cell lines

ValiScreen Dopamine D3 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
PerkinElmer

Membrane Target Systems: Neurotensin NTS1 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 891.00 USD
TSA -Plus DIG, 50-150 slides

TSA Plus DIG Evaluation Kit

TSA® Plus DIG detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra DIG in the localized area of the probe or antibody.
Price Range : 232.00 USD - 1534.00 USD
PerkinElmer

Membrane Target Systems: Serotonin 5HT-6 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 891.00 USD
AlphaLISA immunoassay kits

TAU (human) AlphaLISA Detection Kit

The AlphaLISA® Human Microtubule-associated Protein Tau (TAU) Detection Kit is designed for detection and quantitation of human TAU in cerebrospinal fluid (CSF), buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay. The antibodies used in the kit correspond to clone numbers BT2 and Tau 12.
Price Range : 2827.00 USD - 22100.00 USD

Frataxin (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human Frataxin Detection Kit is designed for detection and quantitation of human frataxin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 773.00 USD - 10300.00 USD
AlphaLISA immunoassay kits

Amyloid ß 1-x (human) AlphaLISA Detection Kit

The AlphaLISA® Human Amyloid beta 1-x (Aß 1-x) Detection Kit is designed for detection and quantitation of human Aß 1-x in cerebrospinal fluid (CSF), buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 2827.00 USD - 22100.00 USD

GTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Guanosine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 458.00 USD - 2139.00 USD
Receptor-expressing cell lines

Serotonin 5-HT2C (ne) AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
PerkinElmer

TSA Plus Fluorescein

TSA® Plus fluorescein detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra fluorescein in the localized area of the probe or antibody.
Price Range : 240.00 USD - 1919.00 USD

UTPαS, [35S]- 1250Ci/mmol, 12.5mCi/ml

Uridine triphosphate, labeled on the alpha phosphate group with 35S.
Price Range : 617.00 USD - 1523.00 USD
Receptor-expressing cell lines

AequoZen FroZen cells, Dopamine D2L, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 836.00 USD
PerkinElmer

Membrane Target Systems: Dopamine D3 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 891.00 USD
PerkinElmer

Membrane Target Systems: Serotonin 5HT2c (human) membrane preparation, in HEK-293 cells. 400 Units.

Cell membranes prepared from HEK293 cells stably-transfected with human serotonin 5HT2c receptor, 400 units.
List Price : 891.00 USD

ATP, [γ-33P]- 3000Ci/mmol, 10mCi/ml

Adenosine triphosphate, labeled on the gamma phosphate group with 33P.
Price Range : 419.00 USD - 1885.00 USD
PerkinElmer

Membrane Target Systems: Serotonin 5HT3 (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Serotonin 5-HT3 receptor, in HEK-293 cells.
List Price : 891.00 USD
Receptor-expressing cell lines

AequoZen FroZen cells, Serotonin 5-HT1A, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 836.00 USD
Receptor-expressing cell lines

ValiScreen Opioid Kappa (OP2) (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
TSA -Plus Tetramethylrhodamine System

TSA Plus TMR

TSA® Plus tetramethylrhodamine (TMR) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra TMR in the localized area of the probe or antibody.
Price Range : 438.00 USD - 1919.00 USD
PerkinElmer

Membrane Target Systems: Serotonin 5HT-2B (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 891.00 USD

TDP-43 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human TDP-43 Detection Kit is designed for detection and quantitation of human TDP-43 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 750.00 USD - 10000.00 USD
TSA Fluorescein System

TSA Fluorescein System

TSA® fluorescein detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra fluorescein in the localized area of the probe or antibody.
Price Range : 467.00 USD - 820.00 USD

dCTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Deoxycytidine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 500.00 USD - 2648.00 USD

ATP, [γ-33P]- 3000Ci/mmol, 10mCi/ml

Adenosine triphosphate, labeled on the gamma phosphate group with 33P.
Price Range : 693.00 USD - 1779.00 USD
Receptor-expressing cell lines

Serotonin 5-HT1A AequoScreen; cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
TSA Cyanine 3/Fluorescein System

TSA Plus Cyanine 3 and Fluorescein System

TSA® Plus multi-fluorophore detection kit, for amplification of multiple signals in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols.
List Price : 756.00 USD
PerkinElmer

Membrane Target Systems: Cannabinoid CB1 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 891.00 USD

dATP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Deoxyadenosine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 517.00 USD - 2139.00 USD
Receptor-expressing cell lines

AequoZen Frozen cells, Serotonin 5-HT2C (edited isoform), Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 835.00 USD
PerkinElmer

Membrane Target Systems: Serotonin 5HT5a (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Serotonin 5-HT5a receptor, in HEK-293 cells.
List Price : 891.00 USD
Receptor-expressing cell lines

Adrenergic alpha 2A AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
Receptor-expressing cell lines

ValiScreen Adrenergic alpha 2A (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.

Mannose, D-[2-3H(N)]-, Specific Activity: 15-30Ci (555GBq-1.11TBq)/mmol, 5mCi (185MBq)

5 mCi quantities of D-[2-3H(N)]-Mannose are available for your research.
List Price : 2711.00 USD
Receptor-expressing cell lines

Opioid Mu (OP3), Human Recombinant, CHO-K1 cAMPZen Frozen cells

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 527.00 USD
TSA Plus DNP (AP)System

TSA Plus DNP (AP)

TSA® Plus DNP (AP) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. The deposited DNP is detected using an anti-DNP alkaline phosphatase, with appropriate substrate.
Price Range : 275.00 USD - 491.00 USD
Receptor-expressing cell lines

AequoZen FroZen cells, Opioid mu, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 835.00 USD
TSA -Plus Cyanine 5 System

TSA Plus Cyanine 5

TSA® Plus Cyanine 5 (Cy5) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy5 in the localized area of the probe or antibody.
Price Range : 240.00 USD - 1919.00 USD
PerkinElmer

Membrane Target Systems: Dopamine D1 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 891.00 USD
Receptor-expressing cell lines

Serotonin 5-HT6 AequoScreen; cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
Protein

GAD67 (human), lyophilized (LANCE)

Human GAD67 standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra GAD67 Detection Kit, but can also be ordered separately.
List Price : 226.00 USD
AlphaLISA immunoassay kits

Amyloid β 1-40 (human) AlphLISA Detection Kit

The AlphaLISA® immunoassay kit for detection and quantitation of human Amyloid β 1-40 (Aβ 1-40) in cerebrospinal fluid (CSF), cell culture supernatants, and other sample types allows for fast, reproducible, and sensitive detection without the need for time-consuming wash steps or complicated assay development.
Price Range : 2827.00 USD - 22100.00 USD
Receptor-expressing cell lines

AequoZen Frozen cells, Serotonin 5-HT2A, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 835.00 USD

UTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Uridine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 458.00 USD - 2343.00 USD
AlphaLISA immunoassay kits

EPO (human) AlphaLISA Detection Kit

The AlphaLISA® Human Erythropoietin (EPO) Detection Kit is designed for detection and quantitation of human EPO in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 2827.00 USD - 22100.00 USD
PerkinElmer

Membrane Target Systems: Opioid Mu (OP3) (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 891.00 USD
PerkinElmer

Membrane Target Systems: Opioid Kappa (OP2) (human) membrane preparation, in HEK-293 cells. 400 Units.

Cell membranes prepared from HEK293 cells stably transfected with human opioid kappa (OP2) receptor, 400 units.
List Price : 891.00 USD
Receptor-expressing cell lines

Serotonin 5-HT2C (edited) AequoScreen; cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
PerkinElmer

Membrane Target Systems: Serotonin 5HT-2A (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 891.00 USD
AlphaLISA immunoassay kits

Amyloid β 1-42 (mouse/rat) AlphaLISA Detection Kit

The AlphaLISA® Mouse/Rat Amyloid beta (Aß 1-42) Detection Kit is designed for detection and quantitation of mouse or rat Aß 1-42 in serum, cerebrospinal fluid (CSF), buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 2827.00 USD - 22100.00 USD

"CNS" 1-50 of 205 Products and Services

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