PerkinElmer

CNS

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You'll gain the greatest possible insights into central nervous system targets and disorders -- in vitro, in situ, and in vivo – using our broad range of products for the neurologic researcher.

Assess mechanisms of central nervous system disease in biochemical, cellular, tissue, and animal models with our biomarker detection kits, cellular and in vivo imaging systems, and tissue pathology solutions, as well as our target-specific radiochemicals, radioligands, and receptor-transfected cell lines and cell membranes.

  • Accurately detect and quantitate biomarkers of central nervous system disease in cells, brain tissue homogenates, cerebrospinal fluid, and other sample types, using our fast, simple, pre-validated kits
  • Effectively study targeted binding using our radiolabeled ligands and steroids
  • Quantitate biomarkers in tissue samples through our industry-leading immunohistochemistry solutions
  • Probe the biological processes in animal models from molecular, functional, and anatomical perspectives with our in vivo imaging systems
  • Gain deeper insights from phenotypic analysis with our high content screening solutions

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Product Type
  • Accessories (34)
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  • Reagents (164)
  • Software and Informatics (6)
Application
  • cAMP (11)
  • Drug Discovery & Development (46)
  • Immunohistochemistry (IHC) (23)
  • In situ hybridization (ISH) (23)
  • Molecular Biology (14)
  • Protein Analysis & Detection (23)
Assay Points
  • 10000 (5)
  • 500 (17)
  • 5000 (11)
Assay Target
  • Aβ 1-42 (1)
  • Aβ oligomers (1)
  • Aβ1-40 (4)
  • Aβ1-42 (2)
  • Aβ1-x (1)
  • Aβ40 (3)
  • Aβ42 (1)
  • BDNF (2)
  • EPO (1)
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  • TDP-43 (2)
Assay Target Class
  • Cytokine (1)
  • GPCR (80)
  • Ion channel (3)
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  • Protein (10)
Assay Validated
  • Binding (72)
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  • cAMP (20)
  • Downstream Phosphorylation (5)
  • GTPγS (19)
  • Inositol Phosphate (3)
Automation Compatible
  • Yes (23)
Buffer
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  • Tricine with stabilizer and dye (12)
Concentration
  • 10 mCi/mL (10)
  • 12.5 mCi/mL (1)
Detection Method
  • Alpha (13)
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  • Time-Resolved Fluorescence (TRF) (10)
  • TR-FRET (10)
Experimental type
  • In vitro (22)
Fluorophore
  • Coumarin (1)
  • Cy3 (8)
  • Cy5 (4)
  • Fluorescein (6)
  • TMR (5)
Format
  • Microplates (23)
  • Slides (23)
Host Cell
  • 1321N1 (4)
  • CHO-K1 (65)
  • HEK293 (13)
  • L Cells (1)
  • UC11 (1)
Label Position
  • alpha (11)
  • gamma (3)
  • Nominally Labeled (1)
Nucleotide
  • ATP (3)
  • CTP (1)
  • dATP (2)
  • dCTP (2)
  • dTTP (1)
  • GTP (1)
  • UTP (4)
Product Brand Name
  • AequoScreen (14)
  • AequoZen (12)
  • AlphaLISA (13)
  • Ancillary Products (2)
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Radionuclide
  • 33P (12)
  • 35S (2)
  • 3H (1)
Radioisotope
  • H-3 (1)
  • P-33 (12)
  • S-35 (2)
Receptor Type
  • 5-Hydroxytryptamine (Serotonin) (38)
  • Adrenergic (10)
  • Cannabinoid (9)
  • Dopamine (8)
  • GABA (4)
  • Galanin (10)
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Target Species
  • Human (21)
  • Mouse (2)
Therapeutic Area
  • Angiogenesis (9)
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Volume
  • 0-50 (75)
  • 51-100 (8)
  • 201-250 (11)
  • 351-400 (32)
  • 451-500 (9)
  • Over 500 (8)
Volume Capacity
  • 150 µL (2)

"CNS" 1-50 of 207 Products and Services

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dATP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Deoxyadenosine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 517.00 USD - 2139.00 USD
Amplification Diluent

TSA Tetramethylrhodamine Tyramide Reagent Pack, Reagents for 100-300 Slides

TSA® tetramethylrhodamine (TMR) reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.
List Price : 655.00 USD
TSA Tetramethylrhodamine System

TSA Tetramethylrhodamine System, for 100-300 Slides

TSA® tetramethylrhodamine (TMR) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra TMR in the localized area of the probe or antibody.
List Price : 820.00 USD
AlphaLISA immunoassay kits

Amyloid β 1-40 (mouse/rat) AlphaLISA Detection Kit

The AlphaLISA® Mouse/Rat Amyloid beta (Aß 1-40) Detection Kit is designed for detection and quantitation of mouse or rat Aß 1-40 in serum, cerebrospinal fluid (CSF), buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 2827.00 USD - 22100.00 USD
PerkinElmer

TSA Plus Biotin

TSA® Plus Biotin detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra biotin in the localized area of the probe or antibody.
Price Range : 409.00 USD - 1534.00 USD
Protein

TDP-43 (human), liquid (LANCE)

Human TDP-43 standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Human TDP-43 TR-FRET Detection Kit, but can also be ordered separately.
List Price : 287.00 USD
TSA -Plus Tetramethylrhodamine System

TSA Plus TMR

TSA® Plus tetramethylrhodamine (TMR) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra TMR in the localized area of the probe or antibody.
Price Range : 438.00 USD - 1919.00 USD
Receptor-expressing cell lines

AequoZen Frozen cells, Serotonin 5-HT5A Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 835.00 USD

Amyloid β 1-42 (high specificity) (human) AlphaLISA Detection Kit

The AlphaLISA® Human Amyloid beta 1-42 (Aß 1-42) (high specificity) Detection Kit is designed for detection and quantitation of human Aß 1-42 in cerebrospinal fluid (CSF), buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 2827.00 USD - 22100.00 USD

dCTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Deoxycytidine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 458.00 USD - 2618.00 USD
TSA Plus DNP (AP)System

TSA Plus DNP (AP)

TSA® Plus DNP (AP) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. The deposited DNP is detected using an anti-DNP alkaline phosphatase, with appropriate substrate.
Price Range : 275.00 USD - 491.00 USD
TSA -Plus TMR/Fluorescein System

TSA Plus Fluorescein and Tetramethylrhodamine (TMR) System

TSA® Plus multi-fluorophore detection kit, for amplification of multiple signals in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols.
List Price : 756.00 USD
Receptor-expressing cell lines

ValiScreen Serotonin 5HT-2A (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
TSA Cyanine 3 System

TSA Cyanine 3 System, for 50-150 Slides

TSA® Cyanine 3 (Cy3) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy3 in the localized area of the probe or antibody.
List Price : 467.00 USD
Receptor-expressing cell lines

cAMPZen Frozen cells, Cannabinoid CB2, Human Recombinant, CHO-K1

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 526.00 USD
Receptor-expressing cell lines

Dopamine D2L AequoScreen Cell Line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.

Amyloid ß 1-x (human) AlphaLISA Detection Kit

The AlphaLISA® Human Amyloid beta 1-x (Aß 1-x) Detection Kit is designed for detection and quantitation of human Aß 1-x in cerebrospinal fluid (CSF), buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 2827.00 USD - 22100.00 USD
Protein

BDNF (human), lyophilized (LANCE)

Human brain-derived neurotrophic factor (BDNF) standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra BDNF Detection Kit, but can also be ordered separately.
List Price : 287.00 USD
Receptor-expressing cell lines

AequoZen FroZen Cells, Galanin GAL2, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 836.00 USD
PerkinElmer

Membrane Target Systems: Serotonin 5HT-2A (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 891.00 USD
PerkinElmer

Membrane Target Systems: Galanin Gal1 (human) membrane preparation, in HEK-293 cells. 400 Units.

Cell membranes prepared from HEK293 cells stably-transfected with human galanin Gal1 receptor, 400 units.
List Price : 866.00 USD
TSA -Plus Cyanine 3 System

TSA Plus Cyanine 3

TSA® Plus Cyanine 3 (Cy3) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy3 in the localized area of the probe or antibody.
Price Range : 240.00 USD - 1919.00 USD

dCTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Deoxycytidine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 500.00 USD - 2648.00 USD

Amyloid β 1-42 (mouse/rat) AlphaLISA Detection Kit

The AlphaLISA® Mouse/Rat Amyloid beta (Aß 1-42) Detection Kit is designed for detection and quantitation of mouse or rat Aß 1-42 in serum, cerebrospinal fluid (CSF), buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 2827.00 USD - 22100.00 USD
Receptor-expressing cell lines

AequoZen FroZen cells, Serotonin 5-HT1A, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 836.00 USD
Receptor-expressing cell lines

Serotonin 5-HT1A AequoScreen; cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
Receptor-expressing cell lines

ValiScreen Opioid Kappa (OP2) (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.

dTTP, [α-33P]- 3000Ci/mmol, 10mCi/ml, 1 mCi

Deoxythymidine triphosphate, labeled on the alpha phosphate group with 33P.
List Price : 2618.00 USD
AlphaLISA immunoassay kits

Aβ 1-40 (human) High Specificity AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human Aβ40 enables the detection and quantitation of human Aβ40 in human cerebrospinal fluid and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps). The assay shows negligible cross-reactivity with other forms of Amyloid beta (i.e. Aβ1-38 and Aβ1-42).
Price Range : 2745.00 USD - 21400.00 USD

Mannose, D-[2-3H(N)]-, Specific Activity: 15-30Ci (555GBq-1.11TBq)/mmol, 5mCi (185MBq)

5 mCi quantities of D-[2-3H(N)]-Mannose are available for your research.
List Price : 2711.00 USD

Aβ(1-40) (human) High Specificity LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human Aβ(1-40) High Specificity Detection Kit is designed for detection and quantitation of human Aβ(1-40) in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 773.00 USD - 10300.00 USD

ATP, [γ-33P]- 3000Ci/mmol, 10mCi/ml

Adenosine triphosphate, labeled on the gamma phosphate group with 33P.
Price Range : 693.00 USD - 1857.00 USD

CTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Cytidine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 438.00 USD - 2351.00 USD
Receptor-expressing cell lines

AequoZen FroZen cells, Adrenergic α2A, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 835.00 USD
Receptor-expressing cell lines

ValiScreen Cannabinoid CB2 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.

UTPαS, [35S]- 1250Ci/mmol, 12.5mCi/ml

Uridine triphosphate, labeled on the alpha phosphate group with 35S.
Price Range : 617.00 USD - 1523.00 USD
AlphaLISA immunoassay kits

Aβ 1-42 (total; human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for total human Aβ (1-42) enables the quantitative determination of total human amyloid beta 1-42 in buffered solution, cell culture supernatants, and cerebrospinal fluid (CSF) using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 2289.00 USD - 20500.00 USD
Receptor-expressing cell lines

AequoZen Frozen cells, Serotonin 5-HT2A, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 835.00 USD
TSA -Plus Cyanine 5 System

TSA Plus Cyanine 5

TSA® Plus Cyanine 5 (Cy5) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy5 in the localized area of the probe or antibody.
Price Range : 240.00 USD - 1919.00 USD
Receptor-expressing cell lines

Nicotinic HM74a Aequoscreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
PerkinElmer

Membrane Target Systems: Serotonin 5HT1a (human) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from cells stably-transfected with human serotonin 5HT1a receptor
List Price : 891.00 USD
PerkinElmer

Membrane Target Systems: GABA B1b in HEK (human) membrane preparation, in HEK-293 cells. 400 Units.

Cell membranes prepared from HEK293 cells stably transfected with human GABA B1b receptor, 400 units.
List Price : 891.00 USD
TSA -Plus DIG, 50-150 slides

TSA Plus DIG Evaluation Kit

TSA® Plus DIG detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra DIG in the localized area of the probe or antibody.
Price Range : 232.00 USD - 1534.00 USD

BDNF (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human BDNF Detection Kit is designed for detection and quantitation of human BDNF in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 750.00 USD - 10000.00 USD
Receptor-expressing cell lines

ValiScreen Serotonin 5HT-1A (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
Receptor-expressing cell lines

Cannabinoid CB1AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
Receptor-expressing cell lines

Neurotensin NTS1 AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
PerkinElmer

Aβ(1-40) (human), lyophilized (LANCE)

Human Aβ(1-40) standard, for use in running standard curves in LANCE TR-FRET no-wash detection assays. This standard is already provided in the LANCE Ultra Human Aβ(1-40) Detection Kit, but can be ordered separately.
List Price : 233.00 USD
AlphaLISA immunoassay kits

Amyloid β 1-42 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for detection and quantitation of human Amyloid β 1-40 (Aβ 1-40) in cerebrospinal fluid (CSF), cell culture supernatants, and other sample types allows for fast, reproducible, and sensitive detection without the need for time-consuming wash steps or complicated assay development.
Price Range : 2827.00 USD - 22100.00 USD
TSA -Plus Fluorescein System

TSA Plus Fluorescein

TSA® Plus fluorescein detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra fluorescein in the localized area of the probe or antibody.
Price Range : 240.00 USD - 1919.00 USD

"CNS" 1-50 of 207 Products and Services

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