PerkinElmer

Cellular Imaging Software

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Acquire, restore, visualize and quantify your image data, then safely share and store it – with quick access for re-analysis again and again.

PerkinElmer offers sophisticated cellular imaging and analysis software to help you perform these tasks more effectively and efficiently, so you can spend more time discovering.

Our robust analytical technology efficiently manages the terabytes of scientific imaging data that are generated by cellular imaging and analysis.

Business Insights (2)
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  • Application Note

    Imaging Bile Canaliculi in 3D Liver Microtissues using the Opera Phenix HCS System

    Analyzing transport of biliary metabolites is essential to predict pharmacokinetics and hepatotoxicity during drug development. A functional impairment of hepatobilary transporters, such as bile salt export pump (BSEP) and multidrug resistance-associated protein 2 (MRP-2), is strongly associated with an increased risk of cholestatic liver injury. Here, we describe a 3D high-content screening assay to study hepatobiliary transporter function in InSphero human liver microtissues. Confocal imaging and automated image analysis were used to quantify BSEP and MRP-2-mediated efflux of fluorescent substrates into bile canaliculi.

  • Application Note

    Measuring FRET using the Opera Phenix High-Content Screening System

    Fundamental processes in living cells, such as apoptosis and signal transduction are controlled by proteins, often acting in concert with other protein partners through protein-protein interactions (PPIs). Inappropriate protein-protein recognition can fundamentally contribute to many diseases, including cancer. Therefore, inhibiting protein-protein interactions represents an emerging area in drug design.

Products & Services (3)
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  • Phenologic 1

    PhenoLOGIC Machine Learning

    PhenoLOGIC enables biologists using Harmony to train the software to develop the image analysis algorithms. While other systems may require an image analysis expert to create an algorithm, PhenoLOGIC uses proprietary machine-learning technology to make it easy for you to do it on your own. Using a learn-by-example approach, images can be segmented with just a few clicks of the mouse and then tailored algorithms developed quickly and easily.
  • Harmony Software 1

    Harmony High-Content Imaging and Analysis Software

    Easily quantify complex cellular phenotypes with Harmony high-content analysis software. Harmony software is designed for Operetta CLS and Opera Phenix high-content screening systems.

    Coming soon!
    Our forthcoming release includes an updated version of PreciScan, which significantly reduces imaging times and data volumes for 3D cell models grown in hydrogels.

  • PreciScan intelligent acquisition software lets you first pre-scan at low magnification

    PreciScan Intelligent Acquisition

    Harness the power of intelligent image acquisition with PreciScan for more efficient high-content imaging and analysis. This optional plug-in for Harmony high-content analysis software enables you to more accurately target your object of interest for significantly reduced acquisition and analysis times, particularly valuable for 3D microtissue and rare event studies.