Cancer Immunotherapy & Immunology

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Better understand the interactions between tumor cells and the immune system within the tumor microenvironment. Our quantitative pathology research solutions for cancer immunology and immunotherapy comprise a powerful workflow solution that includes:

  • Advanced multi-label staining kits
  • Multispectral imaging systems
  • Image analysis software
  • Contract services

 

For detecting biomarkers and providing better data to support the study of cancer, there's finally a complete in situ solution for research applications.

Opal 7 Color Image
Opal 7 Color Image

Stain

Simultaneously detect six biomarkers plus DAPI within a single tissue section. Similar to standard immunohistochemistry, our advanced method is accessible to many laboratories where IHC method development is performed. It allows researchers to use the best primary antibodies, even those raised in the same species, together for multiplex detection. Our staining solutions provide researchers with tools to assess multiple cellular phenotypes at the same while retaining context provided by tissue sections.
Vectra 3 200 slide
Vectra 3 200 slide

Image

PerkinElmer’s quantitative pathology imaging systems deliver high quality data where morphological context is preserved down to the sub-cellular level, removing autofluorescence and increasing signal-to-noise. These systems detect and measure multiple biomarkers, even if overlapping, within a single IHC or IF tissue section or TMA. Low signal levels that were previously undetected can now be captured, and overall quantification is vastly improved - particularly for solid, formalin-fixed, and paraffin-embedded tissues.
inForm image
inForm image

Analyze

PerkinElmer software programs combine the latest technologies with algorithms and intuitive, easy-to-use interfaces, giving you the power to make new, exciting discoveries from your data. Our automated advanced image analysis software used to visualize, analyze, quantify and phenotype cells labeled with multiple biomarkers in situ in FFPE tissue sections.
Phenoptics Research Services
Phenoptics Research Services

Contract Research Services

Want to test the Phenoptics workflow before bringing the capability in house? The PerkinElmer Research Services team can perform multiplexed IHC for up to seven colors (six markers plus DAPI) to help you get results. Our Opal staining method allows all antibodies in a seven-color panel to be selected based on performance and specificity, without consideration of species of origin. Multispectral imaging provides quantitative results regardless of spectral and spatial overlap among fluorescence markers, enabling tissue segmentation, cellular phenotyping, protein expression, and spatial analysis.

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Narrow your results
Product Type
  • Accessories (12)
  • Instruments (6)
  • Reagents (8)
  • Software (2)
Application
  • Immunohistochemistry (IHC) (8)
Assay Target
  • CD20 (3)
  • CD4 (4)
  • CD45RO (1)
  • CD68 (2)
  • CD8 (4)
  • FOXP3 (2)
  • panCK (2)
Automation Compatible
  • No (4)
Detection Method
  • Brightfield (4)
  • Fluorescence (12)
  • MSI (3)
Fluorophore
  • DAPI (4)
  • Opal 520 (8)
  • Opal 540 (6)
  • Opal 570 (7)
  • Opal 620 (6)
  • Opal 650 (4)
  • Opal 670 (2)
  • Opal 690 (6)
Format
  • Slides (1)
Imaging Modality
  • Multispectral Imaging (4)
Maximum Temperature (Celsius)
  • 20-30 (1)
Product Family
  • Mantra (1)
  • Nuance (3)
  • Opal (8)
Target Species
  • Human (4)
Technology
  • Multiplexed Biomarker Imaging (4)

"Cancer Immunotherapy & Immunology" 1-28 of 28 Products and Services

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Vectra_ImageA

Vectra 3.0 Automated Quantitative Pathology Imaging System, 200 Slide

The Vectra® 3 automated quantitative pathology imaging system accurately detects and measures weakly expressing and overlapping biomarkers within a single H&E, IHC or IF intact FFPE tissue section or TMA.

Nuance SNIR Multispectral Imaging System

The Nuance® SNIR near-infrared multispectral imaging system is designed for use on microscopes configured for looking at modern fluorophores that emit in the near-infrared.

Vectra image

Vectra 3.0 Automated Quantitative Pathology Imaging System, 6 Slide

The Vectra® 3 automated quantitative pathology imaging system accurately detects and measures weakly expressing and overlapping biomarkers within a single H&E, IHC or IF intact FFPE tissue section or TMA.

Nuance FX Multiplex Biomarker Imaging System

The Nuance® FX multiplex biomarker imaging system is specifically tailored to meet the majority of all brightfield and fluorescence microscopy imaging applications.

Nuance EX Multispectral Tissue Imaging System

The Nuance® EX multispectral imaging system is ideal for looking at modern fluorophores that emit in the near-infrared.

Mantra Quantitative Pathology Workstation

Mantra™ quantitative pathology workstation with inForm® image analysis software enables easy visualization, quantification and phenotyping of multiple types of immune cells simultaneously in intact FFPE tissue sections for cancer immunology research.

Opal 7 Tumor Infiltrating Lymphocyte Kit

The Opal™ Tumor Infiltrating Lymphocyte Kit enables phenotyping of T cells, B cells and cancer cells within intact FFPE tissue sections.

List Price: 3390.00 USD

OPAL 6-color fIHC Kit

Opal™ is a practical workflow for simultaneous detection of up to 6 tissue biomarkers plus nuclear counterstain, within a single image. The method is similar to standard immunohistochemistry and is accessible to many laboratories where standard IHC method development is performed.

List Price: 4812.00 USD

Opal 4 Lymphocyte Panel Kit

The Opal™ 4 Tumor Lymphocyte Kit enables phenotyping of helper T cells, cytotoxic T cells and B cells within intact FFPE tissue sections.

List Price: 1598.00 USD

OPAL 7-color fIHC Kit

Opal™ is a practical workflow for simultaneous detection of up to 6 tissue biomarkers plus nuclear counterstain, within a single image. The method is similar to standard immunohistochemistry and is accessible to many laboratories where standard IHC method development is performed.

List Price: 1290.00 USD
Opal 5-color flHC Kit, 50 slides

Opal 4-color IHC Kit

Opal™ is a practical workflow for simultaneous detection of up to 6 tissue biomarkers plus nuclear counterstain, within a single image. The method is similar to standard immunohistochemistry and is accessible to many laboratories where standard IHC method development is performed.

List Price: 729.00 USD

Opal 7 Solid Tumor Immunology Kit

The Opal™ 7 Solid Tumor Immunology Kit enables phenotyping of helper T cells, cytotoxic T cells, B cells, macrophages and cancer cells within intact FFPE tissue sections.

List Price: 3390.00 USD

Opal 7 Immunology Discovery Panel Kit

The Opal™ 7 Immunology Discovery Kit enables phenotyping of T cells, B cells and macrophages, with 3 open channels for user-selected targets.

List Price: 2678.00 USD

OPAL 5-color fIHC Kit

Opal™ is a practical workflow for simultaneous detection of up to 6 tissue biomarkers plus nuclear counterstain, within a single image. The method is similar to standard immunohistochemistry and is accessible to many laboratories where standard IHC method development is performed.

List Price: 913.00 USD

inForm Cell Analysis

inForm® Cell Analysis™ enables quantitative per cell analysis of immunohistochemistry (IHC), immunofluorescence (IF), and RNA in-situ hybridization, enabling the separation of weak and spectrally overlapping markers, in single and multiplex assays.

inForm Tissue Finder

inForm® Tissue Finder™ adds exceptional functionality to inForm Cell Analysis to automate the detection and segmentation of specific tissues through powerful patented pattern recognition algorithms. Automation provides consistent reproducible results and enables comparative studies of multiple markers and specimens, supporting researchers to make faster discoveries of the indicators of disease.

"Cancer Immunotherapy & Immunology" 1-28 of 28 Products and Services