PerkinElmer

Cancer Immunotherapy & Immunology

OF

Immuno-oncology has emerged as an exciting area of personalized medicine because of its tremendous potential to harness the powerful immune system to target and destroy cancer cells with few side effects, when targeted to the right tumor at the right time. Researchers are exploring the complex relationship between tumor cells and the immune system within the tumor microenvironment in order to discover new immuno-oncology targets and therapies.

Research Tools

Our cancer immunotherapy research solutions span the entire drug discovery workflow, from drug screening to studies in pre-clinical animal models to imaging of human tumor samples in clinical trials.

  • Immunoassays and reagents
  • Plate readers
  • Advanced multiplex tissue staining kits
  • Image analysis software
  • Quantitative pathology imaging systems
  • High content imaging and analysis
  • In Vivo imaging
  • Contract services

Kits and Reagents for Immuno-Oncology Research

Targeting immune checkpoint inhibitors, such as PD-1, PD-L1, and CTLA-4, has become pivotal in immunotherapy research, and so have monoclonal antibodies (mAbs), whether naked or conjugated with a chemotherapy agent or radioactive particle. Another area of active investigation is chimeric antigen receptor (CAR) T-cell therapy, where T cells are genetically programmed to attach to proteins on the surface of cancer cells. We offer a number of reagent technologies, radioactive and non-rad, for detection of key immuno-oncology targets.
Vectra 3 200 slide
Vectra 3 200 slide

Instrumentation for Immuno-Oncology Research

With our full suite of immuno-oncology products and solutions––including instrumentation and software for in vitro, ex vivo and in vivo models––we enable rapid and targeted discoveries in cancer immunotherapy.
Phenoptics Research Services
Phenoptics Research Services

Contract Services for Immuno-Oncology Research

Looking for an assay that’s not commercially available? Ask us about our custom services for immuno-oncology research including custom labeling of biomolecules, full assay development and transfer, and tissue imaging and analysis.
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"Cancer Immunotherapy & Immunology" 1-50 of 355 Products and Services

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IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina LT In Vivo Imaging System

The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
Quantum GX microCT Imaging System

Quantum GX microCT Imaging System

With microCT imaging systems, speed and resolution are usually a two-system tradeoff – until now. Gain a better understanding of disease and its progression with combined high-speed, low-dose x-ray, and high-resolution microCT imaging in one instrument.
 
Vectra_ImageA

Vectra 3.0 Automated Quantitative Pathology Imaging System

The Vectra® 3 automated quantitative pathology imaging system accurately detects and measures weakly expressing and overlapping biomarkers within a single H&E, IHC or IF intact FFPE tissue section or TMA.

Operetta High-Content Imaging System

As scientists grapple with increasingly complex biological questions, they need to conduct larger, more complex imaging experiments. So they’re turning to the Operetta® High Content Imaging System – the ideal solution for analyzing the inner workings of healthy and diseased cells.
 
FMT In Vivo Imaging Instrument

FMT 2000 In Vivo Imaging System

The FMT 2000 is a workhorse 3D fluorescence tomographic system with the ability to quantitate up to two fluorophores simultaneously.
IVIS SpectrumCT 2D/3D Optical/CT In Vivo Imaging System

IVIS SpectrumCT In Vivo Imaging System

The IVIS® SpectrumCT preclinical in vivo imaging system expands upon the versatility and advanced optical feature sets of the IVIS platform integrated with low dose microCT to support longitudinal imaging.
G8 PET/CT benchtop scanner for preclinical imaging research

G8 PET/CT Preclinical Imaging System

Ultrasensitive and fast multimodal preclinical PET/CT imaging at your benchtop. The G-Platform offers Full Solutions for PET Imaging  and includes the G4 and G8 imaging systems.
G4 Preclinical PET benchtop scanner with integrated X-ray

G4 PET/X-ray Preclinical Imaging System

Ultrasensitive and fast multimodal PET/X-ray imaging at your benchtop. The G-Platform offers and includes the G4 and G8 imaging systems.
IVIS SpectrumBL High Throughput Optical Imaging System

IVIS Spectrum In Vivo Imaging System

The IVIS® Spectrum in vivo imaging system uses a novel patented optical imaging technology to facilitate non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
320X320-Operetta_still_image_35Sec

Operetta CLS High-Content Analysis System

Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS™ high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS™ lets you find even subtle phenotypic changes.

Opera Phenix High-Content Screening System

The Opera Phenix™ High Content Screening System is the premier confocal solution for today's most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera® High Content Screening System, the Opera Phenix is designed for high-throughput, phenotypic screening and assays involving complex disease models, such as live cells, primary cells and microtissues.
FMT In Vivo Imaging Instrument

FMT 4000 In Vivo Imaging System

The FMT 4000 fluorescence tomography imaging system provides the greatest utility of the FMT Systems with the ability to quantitate up to four fluorophores simultaneously. It comes with four excitation laser channels (635, 680, 750, & 790 nm).
IVIS SpectrumBL High Throughput Optical Imaging System

IVIS SpectrumBL High-Throughput In Vivo Optical Imaging System

The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
Mantra benchtop

Mantra Quantitative Pathology Workstation

Mantra quantitative pathology workstation with inForm® image analysis software enables easy visualization, quantification and phenotyping of multiple types of immune cells simultaneously in intact FFPE tissue sections for cancer immunology research.
IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina III In Vivo Imaging System

The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

IVIS Lumina XRMS In Vivo Imaging System

Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.
FMT In Vivo Imaging Instrument

FMT 1000 In Vivo Imaging System

The FMT® 1000 is an entry level 3D fluorescence tomographic system with the ability to quantitate a single fluorophore at a time.
AlphaLisa Analyte 2

BMP-7 (human), lyophilized (AlphaLISA)

Human BMP-7 standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Human BMP-7 Detection Kit, but can be ordered separately.
List Price : 233.00 USD
AlphaLISA immunoassay kits

COL1A1 (human) AlphaLISA Detection Kit, 100 Assay Points

The AlphaLISA® immunoassay kit for human COL1A1 enables the detection and quantitation of human COL1A1 in serum, plasma, cell culture supernatants, cell lysates, and tissue homogenates using a homogeneous AlphaLISA assay (no wash steps).
List Price : 433.00 USD
AlphaLISA immunoassay kits

BMP-7 (human) AlphaLISA Detection Kit, 500 Assay Points

The AlphaLISA® immunoassay kit for human BMP-7 enables the detection and quantitation of human BMP-7 in human serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
List Price : 1433.00 USD

GTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Guanosine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 458.00 USD - 2139.00 USD
AlphaLISA immunoassay kits

E-Cadherin (human) AlphaLISA Detection Kit, 500 Assay Points

The AlphaLISA® immunoassay kit for human E-cadherin enables the detection and quantitation of human E-cadherin in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
List Price : 1433.00 USD

MMP-2 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Matrix Metalloproteinase-2 (MMP2) Detection Kit is designed for detection and quantitation of human MMP2 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay. The kit was designed to detect both MMP2 and pro-MMP2.
Price Range : 1476.00 USD - 9800.00 USD
In vivo Fluorescent Agents

OsteoSense 750EX Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
List Price : 572.00 USD

PSA (human) AlphaLISA Detection Kit

The AlphaLISA® Human Prostate-Specific Antigen (PSA) Detection Kit is designed for detection and quantitation of human PSA in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay. PSA is also known as Kallikrein-related peptidase 3 (KLK3).
Price Range : 1476.00 USD - 9800.00 USD

dATP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Deoxyadenosine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 517.00 USD - 2139.00 USD
AlphaLISA immunoassay kits

CXCL11 (human) AlphaLISA Detection Kit

The AlphaLISA® Chemokine (C-X-C motif) ligand 11 (CXCL11) Detection Kit is designed for detection and quantitation of Human Chemokine (C-X-C motif) ligand 11 (CXCL11) in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1476.00 USD - 9800.00 USD
In vivo Fluorescent Agents

Cat B 750 FAST Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.  
List Price : 696.00 USD
AlphaLISA immunoassay kits

IFN-β (human) AlphaLISA Detection Kit

The AlphaLISA® Human Interferon β (IFNβ) Detection Kit is designed for detection and quantitation of human IFNβ in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay. The analyte in this kit corresponds to the IFN-ß 1a subtype.
Price Range : 1476.00 USD - 9800.00 USD
AlphaLisa Analyte 2

MMP-12 (human), lyophilized (AlphaLISA)

Human MMP-12 standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Human MMP-12 Detection Kit, but can be ordered separately.
List Price : 233.00 USD

RediJect 2-DG Fluorescent Imaging Probe (Standard kit)

XenoLight RediJect 2-DeoxyGlucosone (DG) 750 is a fluorescent imaging probe for in vivo targeting of tumors that typically exhibit elevated glucose uptake rate in comparison to surrounding tissues. To achieve maximum glucose targeting and enhanced tumor uptake, the probe has been designed to contain four 2-DG molecules per dye molecule.  
List Price : 467.00 USD
AlphaLISA immunoassay kits

COL1A1 (human) AlphaLISA Detection Kit, 500 Assay Points

The AlphaLISA® immunoassay kit for human COL1A1 enables the detection and quantitation of human COL1A1 in serum, plasma, cell culture supernatants, cell lysates, and tissue homogenates using a homogeneous AlphaLISA assay (no wash steps).
List Price : 1433.00 USD
AlphaLisa Analyte 2

PTEN (human), lyophilized (AlphaLISA)

Human PTEN standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Human PTEN Detection Kit, but can be ordered separately.
List Price : 240.00 USD

ErbB2 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human ErbB2 (HER2) Detection Kit is designed for detection and quantitation of human ErbB2 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 773.00 USD - 10300.00 USD

PD-L1 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human PD-L1 Detection Kit is designed for detection and quantitation of human PD-L1 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 750.00 USD - 10000.00 USD
AlphaLisa Analyte 2

Human Programmed Cell Death Protein 1 (PD-1), 0.3 µg (lyophilized)

Human Programmed Cell Death Protein 1 (PD-1) standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Human PD-1 Detection Kit, but can be ordered separately.
List Price : 240.00 USD
PerkinElmer

TSA Plus Biotin

TSA® Plus Biotin detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra biotin in the localized area of the probe or antibody.
Price Range : 409.00 USD - 1534.00 USD
AlphaLISA immunoassay kits

Factor VIII (human) AlphaLISA Biotin-Free Detection Kit, 100 Assay Points

The AlphaLISA® Human BDNF Biotin-Free Detection Kit is designed for the quantitative detection of human Brain Derived Neurotrophic Factor (BDNF) in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit is compatible with high-biotin culture media and other sample types that contain high levels biotin.
List Price : 445.00 USD
AlphaLISA immunoassay kits

MMP-7 (human) AlphaLISA Detection Kit, 100 Assay Points

The AlphaLISA® immunoassay kit for human MMP7 enables the detection and quantitation of human pro- and active MMP-7 (hMMP-7) in serum, buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
List Price : 433.00 USD
AlphaLisa Analyte 2

Perlecan (human), lyophilized (AlphaLISA)

Human Perlecan standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Human Perlecan Detection Kit, but can be ordered separately.
List Price : 233.00 USD
PerkinElmer

TSA Plus Cyanine 3

TSA® Plus Cyanine 3 (Cy3) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy3 in the localized area of the probe or antibody.
Price Range : 240.00 USD - 1919.00 USD

EGF (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human EGF Detection Kit is designed for detection and quantitation of human epidermal growth factor in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 773.00 USD - 10300.00 USD

Perlecan (human) AlphaLISA Detection Kit, 5,000 Assay Points

The AlphaLISA® immunoassay kit for human perlecan enables the detection and quantitation of human perlecan (endorepellin) in human serum and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps). The assay showed no cross reacitivity to vimentin, fibronectin, nidogen-1, laminin, or collagen I.
List Price : 9500.00 USD
Protein

COL1A1 (human), lyophilized (LANCE)

Human COL1A1 standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Human COL1A1 TR-FRET Detection Kit, but can also be ordered separately.
List Price : 287.00 USD
Individual Indirect Tyramide Reagent Pack

TSA Biotin Reagent Pack

TSA® biotin reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.
Price Range : 969.00 USD - 4483.00 USD
Bioluminescent Oncology Cell Lines - Bioware

Bioware® Brite Cell Line HCT116 Red-FLuc

Our bioluminescent light-producing oncology cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP) for in vivo studies.
AlphaLISA immunoassay kits

Caspase-3 active AlphaLISA Detection Kit, 500 Assay Points

The AlphaLISA® Human Caspase-3 Detection Kit is designed for detection and quantitation of active caspase-3 in buffered solution or cell lysates, in a homogeneous (no-wash steps, no separation steps) assay.
List Price : 2827.00 USD

EGFR (human) AlphaLISA Detection Kit

The AlphaLISA® EGFR Detection Kit is designed for detection and quantitation of human Epidermal Growth Factor Receptor (EGFR) in cell culture media, human serum, and other sample types using a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 675.00 USD - 9800.00 USD

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