PerkinElmer

Biomarker Detection

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Biomarker detection is key for advancing precision medicine. Use us as your comprehensive source for biomarker detection, from biomarker assay development to primary and secondary screening.

Our products for biomarker detection include:

  • AlphaLISA® immunoassay kits for high sensitivity and large signal to background in a variety of sample matrices, from human serum to cell culture media to CSF
  • LANCE® TR-FRET analyte detection technology
  • DELFIA (dissociation-enhanced lanthanide fluorescence immunoassay) TRF ELISA alternative technology
  • Multimode plate readers
  • Cellular, tissue, and in vivo imaging systems

We design our biomarker detection reagents and kits to excel in applications that rely on high sensitivity, wide dynamic range, and easy automation. With no wash or separation steps necessary, our homogeneous AlphaLISA immunoassays achieve faster run-times than any ELISA assay on the market.

Business Insights (3)
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  • Application Note

    Multiplex 2D Imaging of NIR Molecular Imaging Agents on the IVIS SpectrumCT and FMT 4000

    Epifluorescence (2D) imaging of superficially implanted mouse tumor xenograft models offers a fast and simple method for assessing tumor progression or response to therapy. This approach for tumor assessment requires the use of near infrared (NIR) imaging agents specific for different aspects of tumor biology, and this Application Note highlights the ease and utility of multiplex NIR fluorescence imaging to characterize the complex biology within tumors growing in a living mouse.

  • Application Note

    Imaging Hepatocellular Liver Injury using NIR-labeled Annexin V

    Drug induced liver injury (DILI) is a major reason for late stage termination of drug discovery research projects, highlighting the importance of early integration of liver safety assessment in the drug development process. A technical approach for in vivo toxicology determination was developed using Acetaminophen (APAP), a commonly used over-the-counter analgesic and antipyretic drug, to induce acute hepatocellular liver injury.

  • Poster

    Combined efficacy & toxicity imaging following acute 5-FU treatment of HT-29 tumor xenografts

    Cancer chemotherapy can produce severe side effects such as suppression of immune function and damage to heart muscle, gastrointestinal tract, and liver. If serious enough, tissue injury can be a major reason for late stage termination of drug discovery research projects, so it is becoming more important to integrate safety/toxicology assessments earlier in the drug development process. There are a variety of traditional serum markers, tailored mechanistically to specific tissues, however there are no current non-invasive assessment tools that are capable of looking broadly at in situ biological changes in target and non-target tissue induced by chemical insult.

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1-12 of 736 Products & Services

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  • VictorX_ImageA_320px

    VICTOR Multilabel Plate Reader

    The VICTOR Multilabel plate reader has been replaced by the VICTOR Nivo multimode plate reader. Please contact your local representative for further information, or visit the VICTOR Nivo product page (Part Number - HH35000500).
  • EnSight Multimode Plate Reader

    EnSight Multimode Plate Reader

    The EnSight multimode plate reader combines labeled & image-based cytometry technologies in a single benchtop platform. Imaging & online data analysis is fast: a 384-well plate can be imaged in less than 5 mins. The system’s modular design, combined with workflow-based Kaleido data acquisition & analysis software, gives a truly versatile plate reader that gets users productive quickly.
  • EnVision 2105 multimode plate reader

    EnVision 2105 Multimode Plate Reader

    The EnVision 2105 multimode plate reader provides exceptional speed, ultra-high throughput, and maximum sensitivity across all detection technologies. Tried and tested, the EnVision microplate reader gives you robust performance and reliable data for high throughput screening, time after time.

    The EnVision 2105 model delivers even higher sensitivity for time-resolved fluorescence (TRF) applications, and the Enhanced Security software option includes tools to facilitate 21 CFR Part 11 compliance for integration into regulated environments (GxP). In addition, the Alpha 775 laser module is designed for plant assays.

  • ViewLux uHTS Microplate Imager

    ViewLux uHTS Microplate Imager

    The ViewLux® is the gold standard, ultra high-speed microplate imager, ideal for high throughput screening of compound libraries requiring the ultimate in speed, reliability and high quality data.

    The ViewLux uHTS microplate imager is available outside the EU. Please contact your local representative to discuss alternative products.

  • Trefoil factor 3 (human) AlphaLISA Detection Kit

    The AlphaLISA® Human Trefoil Factor 3 (TFF3) Detection Kit is designed for detection and quantitation of human TFF3 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
    Price Range : 1585.00 USD - 10500.00 USD
  • Il-12 (p70) (human) AlphaLISA Detection Kit

    The AlphaLISA® Human Interleukin 12 (p70) Detection Kit is designed for detection and quantitation of human IL-12 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
    Price Range : 1585.00 USD - 10500.00 USD
  • Protein

    ANGPTL3 (human), lyophilized (LANCE)

    Human angiopoietin-like 3 (ANGPTL3) standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Human ANGPTL3 Detection Kit, but can also be ordered separately.
    List Price : 250.00 USD
  • Amyloid β 1-42 (high specificity) (human) AlphaLISA Detection Kit

    The AlphaLISA® Human Amyloid beta 1-42 (Aß 1-42) (high specificity) Detection Kit is designed for detection and quantitation of human Aß 1-42 in cerebrospinal fluid (CSF), buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
    Price Range : 3036.00 USD - 23700.00 USD
  • Protein

    Adiponectin (human), lyophilized (LANCE)

    Human adiponectin standard, lyophilized, for use in running standard curves in LANCE TR-FRET no-wash detection assays. This standard is already provided in the LANCE Ultra Human Adiponectin TR-FRET Detection Kit, but can be ordered separately.
    List Price : 250.00 USD
  • AlphaLisa Analyte 2

    MMP13 (human), lyophilized (AlphaLISA)

    Human MMP13 (matrix metalloproteinase-13) standard, 0.1 µg, for use in AlphaLISA immunoassays. This vial contains enough analyte to run 10 standard curves. This standard is provided in the AlphaLISA MMP-13 detection kits, but can also be ordered separately.
    List Price : 257.00 USD
  • Protein

    COX-2 (human), liquid (LANCE)

    Human COX-2 standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Human COX-2 TR-FRET Detection Kit, but can also be ordered separately.
    List Price : 308.00 USD
  • LANCE Detection Kit

    IL-8 (human) LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra Human IL-8 Detection Kit is designed for detection and quantitation of human interleukin 8 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 830.00 USD - 11000.00 USD
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