Bioluminescent Bacteria

OF

Infectious disease is a perennially important area for both life science research and drug discovery. Mimic both acute and chronic standard infection protocols using our bioluminescent light-producing bacteria for infectious disease research.

We provide a wide range of bioluminescent bacteria (Gram-positive and Gram-negative) that can be used for drug discovery both in vitro and in vivo imaging (including biofilm models).

Advantages for drug discovery in vitro:

  • Rapid and readily amenable to HTS
  • Sensitive - subtle changes in cellular viability are rapidly detected
  • Inexpensive - no additional substrates needed for bacterial assays

 

Advantages for drug discovery in vivo:

  • Rapid identification of lead drug candidates
  • Real-time efficacy data
  • May decrease drug failure by allowing disease relapse to be monitored in the same animal

 

For research use only. Not for use in diagnostic procedures.

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"Bioluminescent Bacteria" 1-17 of 17 Products and Services

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Staphylococcus aureus - Xen29

Staphylococcus aureus - Xen29 bioluminescent pathogenic bacteria for in vivo and in vitro drug discovery. This product was derived from a parental strain from the American Type Culture Collection, used under license. Staph. aureus-Xen29 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

Salmonella typhimurium - Xen 33

Salmonella typhimurium - Xen33 bioluminescent pathogenic bacteria for in vivo and in vitro drug discovery. This product was derived from the parental strain FDA 1189. S. typhimurium-Xen33 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

Listeria monocytogenes - Xen32

Listeria monocytogenes - Xen32 bioluminescent pathogenic bacteria for in vivo and in vitro drug discovery. This product was derived from the parental strain 10403S. L. monocytogenes-Xen32 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

Staphylococcus aureus - Xen31

Staphylococcus aureus - Xen31 bioluminescent pathogenic bacteria for in vivo and in vitro drug discovery. This product was derived from a parental strain from the American Type Culture Collection, used under license. Staph. aureus-Xen31 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

Shigella dysenteriae - Xen27

S. dysenteriae - Xen27 bioluminescent pathogenic bacteria for in vivo and in vitro drug discovery. This product was derived from the 88A6205 clinical isolate. S. dysenteriae-Xen27 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

Yersinia enterocolitica - Xen25

Yersinia enterocolitica - Xen25 bioluminescent pathogenic bacteria for in vivo and in vitro drug discovery. This product was derived from the parental strain WS2589. Y. enterocolitica-Xen25 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

Escherichia coli - Xen 14

E. coli - Xen14 bioluminescent pathogenic bacteria for in vivo and in vitro drug discovery. This product was derived from the parental strain E. coli WS2572, a clinical isolate from Weihenstephan Culture Collection. E. coli-Xen14 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

Staphylococcus aureus - Xen8.1

Staphylococcus aureus - Xen8.1 bioluminescent pathogenic bacteria for in vivo and in vitro drug discovery. This product was derived from the parental strain 8325-4. Staph. aureus-Xen8.1 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

Yersinia enterocolitica - Xen24

Yersinia enterocolitica - Xen24 bioluminescent pathogenic bacteria for in vivo and in vitro drug discovery. This product was derived from the 91A1854 clinical isolate. Y. enterocolitica-Xen24 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

Staphylococcus aureus - Xen36

Staphylococcus aureus - Xen36 bioluminescent pathogenic bacteria for in vivo and in vitro drug discovery. This product was derived from a parental strain from the American Type Culture Collection, used under license. Staph. aureus-Xen36 possesses a stable copy of the Photorhabdus luminescens lux operon on the native plasmid.

Escherichia coli - Xen 16

E. coli - Xen16 bioluminescent pathogenic bacteria for in vivo and in vitro drug discovery. This product was derived from the parental strain ETEC WS2583. E. coli-Xen16 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

Listeria monocytogenes - Xen19

Listeria monocytogenes - Xen19 bioluminescent pathogenic bacteria for in vivo and in vitro drug discovery. This product was derived from a parental strain from the American Type Culture Collection, used under license. L. monocytogenes-Xen19 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

Staphylococcus aureus - Xen40

Staphylococcus aureus - Xen40 bioluminescent pathogenic bacteria for in vivo and in vitro drug discovery. This product was derived from the parental strain UAMS-1. Staph. aureus-Xen40 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

Pseudomonas aeruginosa - Xen05

P. aeruginosa - Xen05 bioluminescent pathogenic bacteria for in vivo and in vitro drug discovery. This product was derived from a human septicemia isolate (American Type Culture Collection, used under license). P. aeruginosa-Xen05 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

Streptococcus pyogenes - Xen20

Streptococcus pyogenes - Xen20 bioluminescent pathogenic bacteria for in vivo and in vitro drug discovery. This product was derived from Strain 591, Group A Serotype M49. Streptococcus pyogenes-Xen20 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

Pseudomonas aeruginosa - Xen 41

P. aeruginosa - Xen41 bioluminescent pathogenic bacteria for in vivo and in vitro drug discovery. This product was derived from parental strain PAO1. P. aeruginosa-Xen41 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

Proteus mirabilis - Xen 44

Proteus mirabilis - Xen44 bioluminescent pathogenic bacteria for in vivo and in vitro drug discovery. This product was derived from a parental strain from the American Type Culture Collection, used under license. P. mirabilis-Xen44 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

"Bioluminescent Bacteria" 1-17 of 17 Products and Services