Profile Programs

Pharmacology profiling has become an invaluable tool for lead compound selection, optimization and candidate prioritization. Analysis of profile data identifies off-target interactions that can help predict potential side-effects, efficacy and safety of compounds under development before they progress to the more costly stages of preclinical and clinical trials. PerkinElmer's Contract Research Services offers many in vitro profile programs to fit your drug discovery & development needs.

PerkinElmer's Contract Research Services also offers a comprehensive in vivo compound profiling program to assess the therapeutic efficacy of lead or optimized lead compounds by analyzing their effects on key physiological functions in animals, or possibly, by screening for potential side effects caused by the administration of such compound(s).

KinaseScreen PROFILEing

Therapeutic Profiles

Side Effect Profiling

Other Profiles


Products

Abuse Liability

Your compounds and/or drug candidates can be profiled in our Abuse Liability assay panel in nonGLP or...  View more

Cancer/Immunology

Product#Assay TypeAssay ClassAssay Name100-0125BindingEpidermal Growth FactorEGF100-1039BindingEstrogenEstrogen...  View more

Cardiovascular/Renal

Product#Assay TypeAssay ClassAssay Name100-0328BindingAdenosineA1 (h)100-0043BindingAdenosineA2100-0003BindingAdenosineA2A...  View more

CNS Neurological

Product#Assay TypeAssay ClassAssay Name100-0328BindingAdenosineA1 (h)100-0043BindingAdenosineA2100-0003BindingAdenosineA2A...  View more

CNS SEP

Product#Assay TypeAssay ClassAssay Name100-0030BindingAdenosineAD Non selective100-0100BindingAdrenergicAlpha...  View more

CYP Basic

Metabolism related drug drug interactions play an important role in the high attrition rate observed...  View more

CYP Explorer

Metabolism related drug drug interactions play an important role in the high attrition rate observed...  View more

CYP Regulatory

Metabolism related drug drug interactions play an important role in the high attrition rate observed...  View more

Discovery ADME

Cat#Assay TypeAssay ClassAssay Name400-0093EnzymeCYP1A2 (h)CYP1A2 (h)400-0094EnzymeCYP2A6 (h)CYP2A6 ...  View more

Gastrointestinal

Product#Assay TypeAssay ClassAssay Name100-0043BindingAdenosineA2100-0001BindingAdenosineTransporter...  View more

General SEP

Your compounds and/or drug candidates can be profiled in our General Side Effect assay panel in nonGLP...  View more

General SEP Explorer

The General SEP Explorer (GenSEP Explorer) panel contains a total of 112 in vitro assay targets carefully...  View more

General SEP II

The GenSEPII profile contains the assays used to screen a diverse set of 2,300 compounds and generate...  View more

GPCR

Your compounds and/or drug candidates can be profiled in our GPCR assay panel in nonGLP or in GLP-compliant...  View more

In Silico

PerkinElmer offers a major addition to the profile toolbox through the creation of our pharmacoinformatics...  View more

Metabolism

Product#Assay TypeAssay ClassAssay Name100-0328BindingAdenosineA1 (h)100-0101BindingAdrenergicAlpha ...  View more

Pain Inflammation

Cat#Assay TypeAssay ClassAssay Name100-0003BindingAdenosineA2A (h)100-0010BindingAdrenergicBeta 1 (h)100-0011BindingAdrenergicBeta...  View more

PDEScreen

Product#Assay TypeAssay ClassAssay Name200-1068EnzymePDE10A1 (h)PDE10A1 (h)200-0943EnzymePDE10A2 (h)PDE10A2...  View more

RapidKinase 200

RapidKinase 200 Assay ListABLABL1 (E255K)ABL1 (G250E)ABL (H396P)ABL (Q252H)ABL (T315I)ABL1 (Y253F)AKT1AKT2AKT3ALKAMPK1-alphaAMPK-alpha2/beta1/gamma1ARGAurAAurBAurCAXLBLKBMXBRSK1BRSK2BTKCaMK1-alphaCaMK1-deltaCaMK2-alphaCaMK2-betaCaMK2-deltaCaMK2-gammaCaMK4Casein...  View more

RapidKinase 48

Product#Assay TypeAssay ClassAssay Name200-0409EnzymeKinase, ProteinAbl (h)200-0410EnzymeKinase, ProteinAkt1...  View more