Protein-protein Interaction Research Reagents
The interactions and binding of proteins are implicated in a large number of biological processes. The need for efficient, highly sensitive assays to study large protein interactions is increasingly important.
Notable, our Alpha technology is a highly flexible, homogenous, no-wash assay ideal for the measurement of protein interactions and complexes as large as 200 nm in size. A bead-based proximity assay, Alpha technology offers the possibility to assay many biological targets including enzymes, receptor-ligand interactions, low-affinity interactions, second messenger levels, DNA, RNA, proteins, peptides, sugars and small molecules.
The full measurement capabilities of our protein-protein interaction analysis technologies include:
- Transient and stable interactions
- Low-to-high affinity interactions (pM to mM affinity)
- Full-length protein-protein binding
- Peptide-protein
- Receptor dimerization
- Protein-small molecule
- Protein complex interactions
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A Fast and Simple Chemiluminescent Assay for Monitoring of DNA-Protein Interactions
Learn MoreApplicability of AlphaLISA technology to a wide spectrum of complex biological samples
Learn MoreBiochemical binding ADCC assays utilizing AlphaLISA toolbox reagents for the characterization of hIgGs and FcγR1A.
Learn MoreDELFIA Assays: Flexible and Sensitive Tools for Monoclonal Antibody Development
Learn MoreDeveloping a high throughput AlphaLISA assay for screening activity of biologics produced by engineered probiotic microbes
Learn MoreDeveloping a LANCE TR-FRET assay for screening PD-1 and PD-L1 binding inhibitors.
Learn MoreHigh throughput assays to compare performance and stability of an engineered Fc Silent™ antibody to a therapeutic antibody
Learn MoreHigh Throughput assays to compare the performance and stability of an engineered Fc silent antibody to a therapeutic antibody
Learn MoreOptimization and miniaturization of DELFIA TRF assays converted from ELISA.
Learn MoreScreening for inhibitors of PD-1 and PD-L1 binding with AlphaLISA technology
Learn MoreScreening for Inhibitors of PD-1 and PD-L1 Binding with AlphaLISA Technology
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