Alpha Technology
Virtually anything can be measured quickly and easily with Alpha ELISA alternative technology: enzymes, receptor-ligand interactions, kinases, second messenger levels, DNA, RNA, proteins, proteases, peptides, sugars and small molecules.
- Biotherapeutics
- Epigenetics
- Protein:protein interactions
- GPCR research
- Kinase research
The protocol is easy, without wash steps and takes less than 3 hours to set up and run, thus allowing for easy adoption, decreased variability and results in half the time of a traditional ELISA.

Biotherapeutics: Consistent, Reproducible Results
Highly sensitive ELISA alternative to simplify your workflow and ensure consistent, reproducible results. Read more

Epigenetics: Optimized for Simplicity.
The broadest range of highly specific, fully validated research reagents for epigenetic drug targets. Click here for cell based kits and toolbox options.

Handle Large Protein:Protein Interactions Easily
A remarkably efficient and sensitive assay, enabling you to study protein interactions and complexes as large as 200 nm in size. Read more

Cell-based Kinase & Signaling Assays
Novel cellular assays for detection of endogenous phospho-proteins... Read more

Biomarker Kits: Results in 1/2 the time of ELISA
Convert troublesome ELISAs to a superior alternative. For a faster way to measure biomarkers and cytokines, choose from nearly 120 kits for a wide range of therapeutic targets. Read more
Confidence in Your Results: 1000s of Citations and Resources
Only PerkinElmer offers the Alpha expertise and knowledge to deliver the best performance for Alpha Technology as demonstrated by 1000s of citations and resources. Our portfolio gives you a complete solution, from multiple assay platforms to Alpha-certified detection systems, such as the EnSpire® and EnVision® Multimode Plate Readers, automation instrumentation and custom assay development. It's everything you need to ensure consistent, reproducible results across numerous applications - and enhance your research in big and small ways.
Dr. Fritz Poulsen, Novo Nordisk
Dr. Fritz Poulsen works in the ADME & assay technology area in Diabetes Biology and Pharmacology at the Diabetes Research Unit of Novo Nordisk. Fritz says, "We use AlphaLISA sandwich immunoassays due to their good sensitivity and broad working range for testing animal samples from PK studies where very low and very high analyte samples are used.”
Learn more

See Alpha Technology in action
Products
If your analyte of interest is not available as an AlphaLISA immunoassay kit, you have the option of...
View more
Measure mark specific modulation of histone H3 in cell lysatesThe AlphaLISA® Epigenetic Cellular Detection...
View more
Highly sensitive no wash detection for measuring peptide and protein modification by epigenetic enzymes....
View more
Eliminate ELISA limitations - convert to AlphaLISA! - Convert troublesome traditional ELISAs to a much...
View more
The AlphaLISA TruHits kit is designed as a tool for AlphaLISA users to identify the type of hit they...
View more
AlphaScreen®SureFire® is a unique platform for measuring endogenous proteins in cell lysates, as well...
View more
Amplified Luminescent Proximity Homogeneous Assay (ALPHA) is a very
sensitive non-radioactive homogeneous...
View more
Your Reagents Made to OrderWhatever the assay you have in mind, you need the right technologies for ...
View more