The new Multispecies Imaging Module (MSIM) for the PerkinElmer Fluorescence Molecular Tomography (FMT) system opens up the possibility of studying disease models in larger animals. The module is now available for non-invasive quantitative imaging of adult rats in 3-D in the FMT 1500 and 2500LX.
- Better Data: the biology of interest in larger animal models is easier to see and quantify; important rat models of disease can now be imaged by optical tomography.
- Innovation: the first and only 3-dimensional fluorescent imaging system for adult rats (up to 450 grams).
- More Relevance: perform biodistribution studies in rats that are non-invasive, quantitative and within a physiologically relevant context.
- Safety: the heating and anesthesia systems are designed to keep the specimen comfortable and sedated throughout the scan.
- Flexibility: hardware and software components of the new module have been designed to make it easy to switch from imaging mice to rats and back again.
Tomographic image of rat vertebrae
Bigger is Better:
Imaging normal bone turnover in the Lumbosacral vertebrae of the Zucker rat using OsteoSense® 750 (NEV10053). Even in larger sized rats, it is possible to see differences in bone turnover along the vertebrae.
The Multispecies Imaging Module upgrade contains the imaging module for large animals, and an adapter for the standard small animal module.
The MSIM upgrade for FMT includes new internal hardware to accommodate the larger animal cassette.