Quantum FX microCT Imaging System

Product number: QUANUCT

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Quantum FX: Low Dose Computed Tomography

The Quantum FX is the industry's leading in vivo microCT technology purposely designed for longitudinal imaging with optical co-registration enablement for both the IVIS Spectrum and FMT platforms. The Quantum FX features ultra-fast imaging for ultimate throughput while maintaining low dose and high quality images for parametric analysis.

Key Features:

  • Simplified, uncompromised and fast
  • Low dose imaging designed for longitudinal studies
  • High speed imaging and analysis system
    • Intuitive software interface
    • Workflow of up to 30 animals per hour
    • Acquisition, reconstruction and 3D visualization in 45 seconds
  • Co-register functional optical signals with anatomical microCT
  • Monitor events in real-time
  • Image mice, rats and rabbits

The Quantum FX is the most versatile small animal microCT instrument proven to work in broad range of applications in Pulmonary Disease, Cardiovascular Disease, Diabetes, Orthopedics and Dentistry.

Click below to view application videos using the Quantum microCT system

Adipose Tissue Imaging

Bone Cross Section Imaging

Lung Imaging

Speciman Imaging


Quantum FX microCT Applications

Longitudinal microCT imaging

The Quantum FX system is the first stand alone microCT system to deliver high quality images at an X-ray dose low enough to enable true longitudinal microCT for preclinical studies. With the Quantum FX, you can follow and characterize disease progression throughout your complete study using microCT at every imaging point. With a 17 second standard scan time that is designed to simultaneously give low dose and good image quality, you can be confident that your biological model will remain relevant throughout the span of your experiment. Fast imaging and smooth workflow also enable the throughput required to scan cohorts of animals quickly and draw sound conclusions from your experimental data.The Quantum FX system is the first stand alone microCT system to deliver high quality images at an X-ray dose low enough to enable true longitudinal microCT for preclinical studies. With the Quantum FX, you can follow and characterize disease progression throughout your complete study using microCT at every imaging point. With a 17 second standard scan time that is designed to simultaneously give low dose and good image quality, you can be confident that your biological model will remain relevant throughout the span of your experiment. Fast imaging and smooth workflow also enable the throughput required to scan cohorts of animals quickly and draw sound conclusions from your experimental data.
Quantum_microCTLongitudinalStudies.jpg
Longitudinal imaging of MDA-MB-231-D3H2Ln-luc tibial osteolytic lesions


Multimodal Imaging

PerkinElmer has revolutionized pre-clinical Optical Imaging with the IVIS platform. Quantum FX makes microCT imaging as easy as IVIS and allows you to co-register functional optical signals with anatomical microCT throughout the span of your study. Throughput and user workflow have been simplified to seamlessly co-register anatomical and functional data at every step of a longitudinal study. Optical images from the IVIS and FMT platform can seamlessly be co-registered with microCT.
Quantum_microCT_MultimodalImaging.jpg
Optical co-registration of MDA-MB-231-luc-D3H2ln metastases with microCT. Mice were implanted with MDA-MB-231-luc-D2H2Ln cells by intra-cardiac injection and bioluminescence signal was monitored with IVIS Spectrum. The image on the right shows co-registration of luciferase signal and microCT scan. B: Fiducial based registration of FMT image showing cathepsin activity in orthotopic 4T1 tumors detected by ProSense 750 EX with microCT


Metabolic Disease Model

Quantum FX offers the highest-rated Detective Quantum Efficiency (DQE), which results in higher quality images at very low dose levels. The high DQE allows for high speed and low dose imaging with excellent contrast even for tissues such as fat that are traditionally more challenging. When combined with an optional image processing package, this allows for easy differentiation between visceral and subcutaneous fat, an important measure of metabolic health.
Quantum_microCT_MetabolicDisease.jpg 

 Compartment Volume (mm^3)
 Subcutanous (Red) 3093
 Viseral (Green) 5403
 Other Soft Tissue (Gray) 14968
Differentiation between visceral (green) and subcutaneous fat (red) for adipose tissue quantification


Cardiac and Respiratory Gating

For accurate microCT reconstruction in cardiac and respiratory gated applications, it is extremely important to minimize the motion from the diaphragm and heart. Quantum FX’s advanced and simple intrinsic retrospective gating techniques are ideally suited for cardiac and lung function measurements in a contrast enhanced CT. By simply drawing a region of interest over the diaphragm and/or apex of the heart, this optional software will process the image and only use views from a specific point in the respiratory or cardiac cycle, preventing this motion from affecting the reconstructed CT image.
Quantum_microCT_CardiacGating.jpg
The fully automated processing procedure in the Quantum FX can be easily used to automatically reconstruct images at both end diastole and end systole. Cardiac image acquisitions are 4.5 minutes and automatic reconstructions are ideally suited for cardiovascular (A). Respiratory gating improves vascular visualization and provides crisper bone image and improved airway visibility (B)




Review Product Details

PerkinElmer recognizes the importance of proper training to ensure that our customers benefit fully from the capabilities of our instruments.Our Training Academy offers many training options; such as web based training, classroom or customized courses, to help you get the most out of your time in the lab.

Topics range from theory to techniques relating to specific methodology, optimization, and familiarization with instrumentation and related software. Courses are offered at various locations throughout the Americas, as well as Seer Green, England and Turku, Finland.

Learn more about training.

Services & Support

With more than 1,300 service engineers, PerkinElmer provides service and support for instruments worldwide. In addition, our OneSource multivendor service engineers offer instrument repair, maintenance and regulatory compliance services for instruments from virtually any manufacturer.

Services and Support