IVIS 200 Pre-clinical In Vivo Imaging System

Product number: IVIS200

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The IVIS® 200 Series imaging system is an advanced single-view 2D and 3D optical imaging system designed to improve quantitative outcomes of in vivo imaging. It uses a patented optical imaging technology to facilitate non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.

Surface Topography in 3D
A single-view 3D imaging system designed for high throughput, the IVIS 200 Series' instrumentation and software allow researchers to better account for the effects of photon absorption and scattering in tissue, making bioluminescent source measurements more quantitative. Key features on the IVIS Imaging System 200 Series include a custom lens with 5-position carousel and adjustable field of view of 4-26 cm, more uniform light collection, and improved resolution with single cell sensitivity for in vitro use. An integrated fluorescence system (400-900 nm) allows easy switching between fluorescent and bioluminescent spectral imaging applications, while a laser scanner provides 3D surface topography for single-view diffuse tomographic reconstructions of internal sources.

Get a quote on any of our systems or contact us with any questions you may have at invivoimaging@perkinelmer.com.

Resources
Presentation: IVIS Imaging - Overview
In Vivo Imaging Reagents

Review Product Details

Features/Benefits

  • High-sensitivity in vivo imaging of fluorescence and bioluminescence
  • High throughput (5 mice) with 26 cm field of view
  • High resolution (to 60 microns) with 3.9 cm field of view
  • Dual 12-position emission filter wheels (24-position total) and 12-position excitation wheel
  • A set of four filter pairs for fluorescent imaging come standard with the instrument, in addition to a set of four background filters for subtraction of tissue autofluorescence
  • 25 x 25 cm alignment grid on the imaging platform ensures consistent accurate placement of animals for imaging
  • Spectral imaging filters that acquire images at different wavelengths (ranging from 560 nm to 660 nm) facilitate 3D diffuse tomographic reconstruction and determination of the
  • depth and location of a bioluminescent reporter
  • Heated animal shelf (up to 40˚ C)
  • NIST traceable absolute calibrations
  • Gas anesthesia inlet and outlet ports
  • Class I Laser Product

PerkinElmer recognizes the importance of proper training to ensure that our customers benefit fully from the capabilities of our instruments.Our Training Academy offers many training options; such as web based training, classroom or customized courses, to help you get the most out of your time in the lab.

Topics range from theory to techniques relating to specific methodology, optimization, and familiarization with instrumentation and related software. Courses are offered at various locations throughout the Americas, as well as Seer Green, England and Turku, Finland.

Learn more about training.

Services & Support

With more than 1,300 service engineers, PerkinElmer provides service and support for instruments worldwide. In addition, our OneSource multivendor service engineers offer instrument repair, maintenance and regulatory compliance services for instruments from virtually any manufacturer.

Services and Support

Applications

  • Infectious Disease
  • Inflammation
  • Metabolic Diseases
  • Neurology
  • Gene Therapy
  • Stem cell Biology
  • Cardiovascular Disease
  • Immunology & Transplantation Biology
  • Toxicology (PDF)
  • Drug Metabolism Studies

Specifications

Power Requirements

20 Amps for 120VAC or 10 Amps for 230VAC

Net Weight

<275 kg/600 lbs

Camera Sensor

Back-thinned, back-illuminated Grade 1 CCD

CCD

Size26 x 26 mm
Operating TemperatureNominal –105 • C

Imaging Pixels

2048 x 2048

Quantum Efficiency

>85% 500–700 nm; >50% 350-950 nm

Pixel Size

>13.5 µm square

Minimum Detectable Radiance

<70 photons/s/sr/cm2

Minimum Image Pixel Resolution

60 µm (at f/1)

Read Noise

<5 electrons RMS

Dark Current (Typical)

<100 electrons/s/cm2

Filter Slots

Fluorescence Excitation25 mm diameter 12-position (11-filter capacity)
Fluorescence Emission60 mm diameter 24-position (22-filter capacity)

Lens

f/1– f/8, 1.5x, 2.5x, 5x, 7.5x, 10x magnifications

Field of View

3.9 x 3.9 cm to 26 x 26 cm (3.9, 6.5, 13, 19.5, 26 cm)

Scanning Laser

<1 mW power at 532 nm

Stage Temperature

Ambient to 40 ˚ C

Imaging Chamber Dimensions

51 cm x 51 cm x 66 cm (D x W x H)

Lamp

150 W Quartz halogen 3250 • Kelvin

Fluorescence Field of View

6.5, 13, 19.5, 26 cm (fluorescence not available at 3.9 cm field of view)

Background (autofluorescence and leakage)

<3 part in 106 typical