LabChip® GX

Product number: 122000

Unit price: This product is not available for online purchase.

Unit size: 1/EA

Quick and accurate analysis of RNA and DNA samples

  • Complete assessment of RNA quality for better gene expression data
  • Exact sizing and quantitation of DNA fragments
  • Extreme accuracy with resolution down to 5 bp and sensitivity of 0.1ng/ul
  • Flexible with 96 and 384 well compatibility
  • Comprehensive and quantitative analysis with LabChip GX software

The LabChip GX is the most accurate and advanced nucleic acid separations system available. Like its predecessor the LabChip90, the GX suite of instruments utilizes PerkinElmer's innovative microfluidics technology to perform reproducible, high-resolution, eletrophoretic separations. Whether analyzing RNA integrity for better gene expression data or assessing PCR fragments for resequencing applications, the LabChip GX instrument accelerates your research and helps you generate more meaningful data, faster.

When speed, accuracy and ease-of-use are paramount, the LabChip GX is the perfect solution. With sample acquisition time less than a minute the instrument can thoroughly analyze 96 samples in less than an hour, virtually eliminating throughput bottlenecks and improving efficiency. In addition to the instrument, the complete system also includes the LabChip GX software for data analysis. This advanced data management suite allows users to visualize results via an electropherogram or virtual gel view. Additionally it provides data in tabular form, which can then be analyzed or easily exported into a spreadsheet format.

PerkinElmer RQS for RNA Analysis

RNA metrics such as peak heights, peak areas, and concentration are used to determine an RQS (RNA Quality Score) number for each sample. The PerkinElmer RQS is a calculated score that rates the quality of RNA samples. The RQS has been validated to correlate well with Agilent’s RIN (RNA Integrity Number) and follows the same 0-10 scale rating. Results comparing RIN to RQS for the same samples run on both LabChip GX and Agilent’s Bioanalyzer 2100 typically show <10% deviation. For more detailed information about the PerkinElmer RQS, please refer to ‘RNA Quality Score (RQS) Calculation and Correlation to RIN’, LabChip GX Application Note 402 available through the Reference Section.

Supporting Regulatory Compliance

PerkinElmer LabChip GX/GXII instruments with LabChip GxP Software are computerized systems designed to automate the analysis of DNA, RNA or proteins using PerkinElmer Sipper Chip technologies. The systems allow the users to create, modify, and maintain the records in electronic form and allow the users to perform electronic signatures on the records generated from the system. It takes a combination of administrative controls, procedural controls, and technical controls for the users of a computerized system to comply with 21 CFR Part 11 regulations. The LabChip GxP Software contains built-in technical controls and features specifically designed to support the users for 21 CFR Part 11 compliance. These technical controls and features include user account management and access controls, device check, enforcing permitted sequencing of steps, audit trails, record copying, record retention, system documentation, and electronic signature controls.

Compliance Features:

  • User Account Management
  • Audit trails
  • Electronic Signature Controls
  • Central Data Repository

Review Product Details

Features/Benefits

  • Quantitative sizing and concentration
  • 96 and 384 well compatible
  • 30 to 60 second sample processing
  • Hit picking capable
  • Automation compatible
  • Integrated bar code reader for sample tracking
  • Class I product

Posters

Applications

DNA Analysis
DNA fragment quantitation and detection

  • PCR
  • RT-PCR
  • Sequencing
  • Genotyping

RNA Analysis
RNA quality assessment and quantitation

  • Microarrays
  • qRT-PCR
  • Biobanking
  • Sequencing

Exome Capture

Sequencing Library Preparation Workflows

Specifications

Power Requirements
100/110/230 V AC, 50/60 Hz

Dimensions
Height 18.28" (46.4 cm)
Width 18.28" (46.4 cm)
Depth 25.57" (64.9 cm)

Net Weight
100 lbs (45.5 kg)

Temperature Range
18-26°C

Power Consumption
460 VA (460 W)

Plate Formats
96- and 384-well

Excitation/Emission Wavelengths
635 nm and 700 nm

Humidity Range
30-70% relative, non-condensing

Product Laser Safety Rating
Class 1

Comments

“Microfluidic analysis of experiments moves the bottle neck from data analysis to experimental design.”
NCI-SAIC, COG 2009

“LabChip enables us to perform experiments in an afternoon that would have required a month.”
Biogen-Idec, COG 2009

“Finally, the process that we have described reduces both experimentation cost and time while increasing throughput, making possible what–if experiments that, up to now, had been either prohibitively expensive or too complex to perform. This process results in better solutions, decreased development time and increased productivity.”
Vertex, COG ’09 & ’07 and Anal. Biochem., 2006: 351 p122

“LabChip allowed for detection of deglycosylated profile not detected with other analytical techniques (SDS PAGE, usual glycan mapping, HPLC).”
EMD Serono, COG 2008

“Microchip CE-SDS, under both non-reducing and reducing conditions, can be used in a variety of antibody product screening assays. The microchip analyses provide sufficient resolution and sensitivity for this purpose but on a time scale approximately 70 times faster (41 s versus 50 min per sample) than conventional CE separation.”
Amgen, Electrophoresis, 2008: 29 p4993

”The results of our studies suggest the LabChip platform offers a unique high throughput platform with high resolution and high sensitivity. The LabChip technology appears to be extremely well suited for routine identification and quantification of HMW-GS especially for purposes of wheat quality screening and wheat cultivar development activities.”
LaSalle, COG 2008

“We achieved material cost savings of 50%+, and time savings of 75% per screen!”
Univ. of Wisconsin, Midwest LRIG 2007

“Caliper was willing to work with us to develop the 12 kb chip and provided tremendous support and interactions. We are very satisfied with the LabChip, will likely purchase 1-2 more and recommend this platform to our colleagues.”
Dow AgroSciences, COG 2007

Software

Software Downloads: LabChip®

Please go to the Software Downloads page to download this software.