(-)-CGP-12177, [5, 7-3H]-

CGP 12177 is a beta1/beta2-adrenergic (b1/b2) receptor antagonist with partial agonist activity at the beta 3 (b3) adrenergic receptor. Beta-Adrenergic receptors (β-adrenoreceptors) are G-Protein Coupled Receptors (GPCR) that have a role in cardiopulmonary, liver, GI, kidney, regulation of weight and more. The hydrophilic beta-adrenergic radioligand [3H]CGP-12177 was developed as a radioligand with antagonist properties for binding studies of beta-adrenergic receptors. Application of [3H] CGP-12177 can be found in: clinical pharmacology, brain research, biological psychiatry, neuro-psychopharmacology, etc. PerkinElmer offers (-)-CGP-12177, [5,7-3H]- in many units sizes including: 1 mCi, 250 uCi, and 25 uCi depending on your drug discovery and research needs.