Transporters

Transporters are integral membrane proteins involved in the movement of molecules by facilitated diffusion or active transport across a biological membrane. One class of these transporters is located in the synaptic membrane of neurons and serve to remove neurotransmitters from the synaptic cleft. Another class, also located in neurons, are called vesicular transporters and serve to move neurotransmitters into synaptic vesicles. Many of these transporters in are involved in psychiatric disorders. An additional group are the ATP-binding cassette transporters (ABC-transporters). They also are transmembrane proteins and function in the transport of a wide variety of substrates across extra- and intracellular membranes, including metabolic products, lipids and sterols, and drugs. ABC transporters are involved in drug resistance, cystic fibrosis, bacterial multi-drug resistance and a range of other inherited human diseases.

Product#
Assay Type
Assay Class
Assay Name
300-0214CellularAdenosineTransport AOT-T es (h)
300-0215CellularAdenosineTransport AOT-T es/cs (h)
100-0047BindingAdenosineTransporter AOT
100-0001BindingAdenosineTransporter AOT (h)
300-0216CellularAnandamideTransport AMT-T (h)
300-0217CellularCholineTransport CHOL-T
300-0331CellularDopamineTransport, DAT-T
100-0015BindingDopamineTransporter, DAT
100-0123BindingDopamineTransporter, DAT (h)
300-0218CellularGABATransport GABA-T
300-0219CellularGlutamateTransport GLUT-T
300-0332CellularNorepinephrineTransport NET-T
300-0404CellularNorepinephrineTransport NET-T (h)
100-0048BindingNorepinephrineTransporter NET
100-0146BindingNorepinephrineTransporter NET (h)
100-0806BindingP-Glyocoprotein (PGP)Transporter P-Glycoprotein (PGP) (h)
300-0220CellularSerotoninTransport SERT-T (h)
100-0056BindingSerotoninTransporter SERT
100-0099BindingSerotoninTransporter SERT (h)
300-0554CellularVesicular MonoamineTransport VMAT1
300-0555CellularVesicular MonoamineTransport VMAT2
100-0751BindingVesicular MonoamineTransporter VMAT2