ValiScreen GPCR Cell Lines

PerkinElmer has the largest collection of pharmacologically validated recombinant GPCR cell lines for GPCR research. Our ValiScreen cell lines are validated with saturation and competition binding, and approximately 30% of these protocols have been adapted for GTPϒS binding and functional studies.

We have the technology and instrument platform to address all GPCR targets, regardless of the receptor signaling pathway. These include the measurement of intracellular calcium, cAMP, phosphor-ERK and receptor gene expression. In addition we have the world's most comprehensive collection of radiolabelled ligands for binding studies, a solution for measuring GTPϒS binding and a comprehensive collection of microplates to support all of the above platforms.

Visit the cell lines, frozen cells & membranes product listing to understand the validation for each product.



Products

Adenosine

Stable recombinant cell line expressing the Adenosine, A2a receptor. Human recombinant, in HEK-293 ...  Zobacz więcej

Adrenergic

Stable recombinant cell line expressing the Adenosine, A2a receptor. Human recombinant, in HEK-293 ...  Zobacz więcej

Adrenomedullin

Stable recombinant cell line expressing the Adrenomedullin, CRLR + RAMP3 receptor. Human recombinant,...  Zobacz więcej

Angiotensin

Stable recombinant cell line expressing the Angiotensin, AT1 receptor. Human recombinant, in CHO-K1...  Zobacz więcej

Apelin

Stable recombinant cell line expressing the Apelin, APJ receptor. Human recombinant, in CHO-K1 host...  Zobacz więcej

Bombesin

Stable recombinant cell line expressing the Bombesin, BB2 receptor. Human recombinant, in CHO-K1 host...  Zobacz więcej

Bradykinin

Stable recombinant cell line expressing the Bradykinin, B2 receptor. Human recombinant, in CHO-K1 host...  Zobacz więcej

Calcitonin Gene Related Peptide

Stable recombinant cell line expressing the CGRP, CRLR + Ramp1 receptor. Human recombinant, in CHO-K1...  Zobacz więcej

Cannabinoid

Stable recombinant cell line expressing the Cannabinoid, CB2 receptor. Human recombinant, in CHO-K1...  Zobacz więcej

Chemoattractant

Stable recombinant cell line expressing the Chemoattractant, C3a receptor. Human recombinant, in CHO-K1...  Zobacz więcej

Chemokine

Stable recombinant cell line expressing the Chemokine, CCR2b receptor. Human recombinant, in CHO-K1...  Zobacz więcej

Cholecystokinin

Stable recombinant cell line expressing the Cholecystokinin, CCKA receptor. Human recombinant, in 1321N1...  Zobacz więcej

Corticotropin-Releasing Factor

Stable recombinant cell line expressing the Corticotropin-Releasing Factor, CRF1 receptor. Human recombinant,...  Zobacz więcej

Dopamine

Stable recombinant cell line expressing the Dopamine, D3 receptor. Human recombinant, in CHO-K1 host...  Zobacz więcej

Endothelin

Stable recombinant cell line expressing the Endothelin, ETB receptor. Human recombinant, in CHO-K1 ...  Zobacz więcej

Free Fatty Acid

Stable recombinant cell line expressing the Free Fatty Acid FFA1 (GPR40) receptor. Human recombinant,...  Zobacz więcej

GABA

Stable recombinant cell line expressing the GABA, GABAb1a/GABAb2 receptor. Human recombinant, in CHO-K1...  Zobacz więcej

Galanin

Stable recombinant cell line expressing the Galanin, Gal2 receptor. Human recombinant, in CHO-K1 host...  Zobacz więcej

Ghrelin

Stable recombinant cell line expressing the Ghrelin receptor. Human recombinant, in CHO-K1 host cell....  Zobacz więcej

MCH

Purinergic

Mammalian cell lines stably expressing recombinant GPCRs have long been used as a source of receptors...  Zobacz więcej

Serotonin

Mammalian cell lines stably expressing recombinant GPCRs have long been used as a source of receptors...  Zobacz więcej

Somatostatin

Mammalian cell lines stably expressing recombinant GPCRs have long been used as a source of receptors...  Zobacz więcej

Vasopressin

Mammalian cell lines stably expressing recombinant GPCRs have long been used as a source of receptors...  Zobacz więcej