These agents are based on fluorescent nanoparticles (20-35 nm). With an approximate half-life in plasma of 20 h, they are well suited for prolonged monitoring of blood vessels and observing phenomena such as blood leakage in tumors, inflammation and angiogenesis.
- Excellent for in vitro and in vivo imaging using IVM, FMT, FRI, FACS and fluorescence microscopy
- Work with superbright, stable fluorescence for longer times than previously possible
- Ideal for in vivo imaging applications
- Biocompatible, minimal cytotoxicity, narrow size distribution, highly functionalized
- Intravital microscopy of vasculature (AngioSPARK 680)
- Superbright imaging of blood vessels by IVM over 4-6 h
Image: IVM of murine auricular vasculature using a BioRad In Vivo Confocal Microscope at time intervals shown after injection of AngioSPARK 680. Courtesy of Ralph Weissleder, MD, PhD, Center for Molecular Imaging, Massachusetts General Hospital, Harvard University
Imaging subcutaneous and deep tissues (AngioSPARK 680)
Surface tumors and heart are discriminated using AngioSPARK 680 and FMT System
PerkinElmer recognizes the importance of proper training to ensure that our customers benefit fully from the capabilities of our instruments.Our Training Academy offers many training options; such as web based training, classroom or customized courses, to help you get the most out of your time in the lab.
Topics range from theory to techniques relating to specific methodology, optimization, and familiarization with instrumentation and related software. Courses are offered at various locations throughout the Americas, as well as Seer Green, England and Turku, Finland.
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